Clinical and pathological characteristics of Fabry disease combined with IgA nephropathy in Chinese patients

2017 ◽  
Vol 87 (04) ◽  
pp. 188-195 ◽  
Author(s):  
Nannan Yang ◽  
Xia Wang ◽  
Feng Xu ◽  
Caihong Zeng ◽  
Jinquan Wang ◽  
...  
Keyword(s):  
Fabry Disease ◽  
Iga Nephropathy ◽  
Chinese Patients ◽  
Pathological Characteristics

Epidemiology and risk factors for progression in Chinese patients with IgA nephropathy

2020 ◽  
Author(s):  
Yang Liu ◽  
Wei Wei ◽  
Chengyuan Yu ◽  
Li Xing ◽  
Mingao Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Iga Nephropathy ◽  
Chinese Patients

scholarly journals Renal Pathology in Two Chinese Patients with Concomitant IgG4-Related Disease (IgG4-RD) and IgA Nephropathy (IgAN)

2015 ◽  
Vol 17 (2) ◽  
pp. S36
Author(s):  
C.K.Y. Poon ◽  
H.L. Tang ◽  
Y.F. Mak ◽  
H.M. Cheng ◽  
L.Y. Wong ◽  
...  
Keyword(s):  
Iga Nephropathy ◽  
Renal Pathology ◽  
Chinese Patients ◽  
Related Disease ◽  
Igg4 Related Disease

scholarly journals The Influence of ACE Insertion/Deletion Gene Polymorphism on the Risk of IgA Nephropathy: A Debatable Topic

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Fen-Fen Chu ◽  
Shi-Kun Yang ◽  
Wen-Li Zeng
Keyword(s):  
Gene Polymorphism ◽  
Angiotensin Converting Enzyme ◽  
Iga Nephropathy ◽  
Gene Polymorphisms ◽  
Pooled Analysis ◽  
Chinese Patients ◽  
Converting Enzyme

Background. The connection between angiotensin-converting enzyme insertion/deletion (ACE I/D) gene polymorphisms and IgA nephropathy (IgAN) was conflicting. This pooled analysis was performed to explore this issue. Methods. All eligible investigations were identified from various electronic databases, and the pooled analysis was evaluated using Stata software. Results. 27 studies with 2538 IgAN cases and 3592 controls were included. In overall subjects, ACE D allele, DD, and II genotype were associated with IgAN susceptibility (D vs. I: OR = 1.21, 95% CI: 1.10–1.32, P < 0.001 ; DD vs. ID + II: OR = 1.38, 95% CI: 1.20–1.60, P < 0.001 ; and II vs. DD + ID: OR = 0.83, 95% CI: 0.73–0.95, P = 0.007 ). In Asian and Chinese patients, ACE I/D gene polymorphism was also correlated with IgAN vulnerability. Moreover, ACE D allele, DD, and II genotype were correlated with the progression of IgAN (D vs. I: OR = 1.37, 95% CI: 1.09–1.73, P = 0.008 ; DD vs. ID + II: OR = 1.57, 95% CI: 1.06–2.31, P = 0.024 ; and II vs. DD + ID: OR = 0.69, 95% CI: 0.49–0.99, P = 0.045 ). Conversely, in Caucasian subjects, there was no link between ACE I/D gene polymorphism and the risk of IgAN. Conclusion. ACE I/D gene polymorphism was correlated with the vulnerability and progression of IgAN in Asian and Chinese patients, and ACE D allele and DD homozygote genotype could be adverse factors for IgAN, while the II homozygote genotype could be an advantage factor. But, no significant association was found between ACE I/D gene polymorphism and IgAN in Caucasians.

A Multicenter Application and Evaluation of the Oxford Classification of IgA Nephropathy in Adult Chinese Patients

2012 ◽  
Vol 60 (5) ◽  
pp. 812-820 ◽  
Author(s):  
Cai-Hong Zeng ◽  
Weibo Le ◽  
Zhaohui Ni ◽  
Minfang Zhang ◽  
Lining Miao ◽  
...  
Keyword(s):  
Iga Nephropathy ◽  
Chinese Patients ◽  
Oxford Classification ◽  
The Oxford Classification

Two novel mutations in the α-galactosidase A gene in Chinese patients with Fabry disease

2003 ◽  
Vol 63 (3) ◽  
pp. 205-209 ◽  
Author(s):  
C-C Yang ◽  
L-W Lai ◽  
O Whitehair ◽  
W-L Hwu ◽  
S-C Chiang ◽  
...  
Keyword(s):  
Fabry Disease ◽  
Chinese Patients ◽  
Novel Mutations
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