Natural History and Prognostic Factors of IgA Nephropathy Presented with Isolated Microscopic Hematuria in Chinese Patients

2007 ◽  
Vol 106 (4) ◽  
pp. c157-c161 ◽  
Author(s):  
Peicheng Shen ◽  
Liqun He ◽  
Yi Li ◽  
Yunman Wang ◽  
May Chan
Diagnosis ◽  
2015 ◽  
Vol 2 (4) ◽  
pp. 211-216 ◽  
Author(s):  
Michelle Clark ◽  
Stephen Aronoff ◽  
Michael Del Vecchio

AbstractAsymptomatic microscopic hematuria is common in children. No systematic review providing an evidence based approach for the differential diagnosis of these children has been performed.Multiple data bases were search. The PRISMA criteria were followed. Data regarding the etiology of the hematuria were extracted using a standardized extraction tool. Seven studies encompassing 1092 children (857 with isolated microscopic hematuria and 235 with combined microscopic hematuria and proteinuria), comprise this review. A total 42.4% of isolated microscopic and 81.3% of microscopic hematuria and proteinuria subjects had identified etiologies. Thin basement membrane nephritis (15.2%), IgA nephropathy (10.4%), and hypercalciuria without nephrolithiasis (7.7%), were the most common etiologies among children with isolated microscopic hematuria. IgA nephropathy (44.3%), thin basement membrane disease (12.8%), and mesangial proliferative glomerulosclerosis (8.9%) were the most common etiologies among children with combined microscopic hematuria and proteinuria.The present study provides an evidenced based resource, based on a systematic review, for the differential diagnosis of asymptomatic hematuria in children. Additionally, these observations suggest that children with isolated microscopic hematuria should be followed for persistence of hematuria or the development of proteinuria. Children with combined microscopic hematuria and proteinuria should be comprehensively evaluated.


2009 ◽  
Vol 24 (4) ◽  
pp. 356 ◽  
Author(s):  
Byung Soo Kim ◽  
Yong Kyun Kim ◽  
Young Shin Shin ◽  
Young Ok Kim ◽  
Ho Cheol Song ◽  
...  

2004 ◽  
Vol 6 (2) ◽  
pp. A5
Author(s):  
K.Y. Chung ◽  
C.C. Szeto ◽  
K.F. To ◽  
F.M. Lai ◽  
K.M. Chow ◽  
...  

Author(s):  
Yang Liu ◽  
Wei Wei ◽  
Chengyuan Yu ◽  
Li Xing ◽  
Mingao Wang ◽  
...  

2021 ◽  
Vol 49 (5) ◽  
pp. 030006052110132
Author(s):  
Jie Sun ◽  
Sha He ◽  
Hong Cen ◽  
Da Zhou ◽  
Zhe Li ◽  
...  

Objective To explore prognostic factors and develop an accurate prognostic prediction model for angioimmunoblastic T-cell lymphoma (AITL). Methods Clinical data from Chinese patients with newly diagnosed AITL were retrospectively analysed. Overall survival (OS) and progression-free survival (PFS) were estimated using Kaplan-Meier method survival curves; prognostic factors were determined using a Cox proportional hazards model. The sensitivity and specificity of the predicted survival rates were compared using area under the curve (AUC) of receiver operating characteristic (ROC) curves. Results The estimated 5-year OS and PFS of 55 eligible patients with AITL were 22% and 3%, respectively. Multivariate analysis showed that the presence of pneumonia, and serous cavity effusions at initial diagnosis were significant prognostic factors for OS. Based on AUC ROC values, our novel prognostic model was superior to IPI and PIT based models and suggested better diagnostic accuracy. Conclusions Our prognostic model based on pneumonia, and serous cavity effusions at initial diagnosis enabled a balanced classification of AITL patients into different risk groups.


2009 ◽  
Vol 36 (5) ◽  
pp. 1026-1031 ◽  
Author(s):  
TING ZENG ◽  
YU-QIONG ZOU ◽  
MEI-FANG WU ◽  
CHENG-DE YANG

Objective.To describe the onset, clinical features, prognostic factors, and treatment of adult-onset Still’s disease (AOSD) in cases from China.Methods.Sixty-one Chinese patients with AOSD were analyzed retrospectively.Results.Common clinical features were fever (100.0%), rash (88.5%), and arthritis (82.0%). The laboratory findings were as follows: leukocytosis (83.6%), increased erythrocyte sedimentation rate (100.0%), elevated transaminase concentrations (23.0%), elevated ferritin levels (79.6%), negative antinuclear antibody (88.5%), and negative rheumatoid factor (88.5%). Of the 61 patients, 44.3% exhibited a monocyclic disease pattern, 29.5% experienced disease relapse at least once, 16.4% exhibited chronic articular course, and 9.8% died; most deaths were due to pulmonary infection and respiratory failure. Based on the disease course, we divided the 61 patients into 2 groups: those with favorable outcome (cyclic disease course, n = 45) and unfavorable outcome (chronic disease course or death, n = 16). We analyzed the prognostic factors for the 2 groups, and found that pleuritis, interstitial pneumonia, elevated ferritin levels, and failure of fever to subside after 3 days of prednisolone at 1 mg/kg/day were unfavorable prognostic factors for patients with AOSD.Conclusion.Patients with AOSD had complex symptoms with no specific laboratory findings. Our results indicate that AOSD is not a relatively benign disease, especially in cases that are refractory to high doses of prednisone.


2015 ◽  
Vol 17 (2) ◽  
pp. S36
Author(s):  
C.K.Y. Poon ◽  
H.L. Tang ◽  
Y.F. Mak ◽  
H.M. Cheng ◽  
L.Y. Wong ◽  
...  

BMC Neurology ◽  
2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Inés González-Suárez ◽  
Irene Sanz-Gallego ◽  
Francisco Javier Rodríguez de Rivera ◽  
Javier Arpa

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