scholarly journals Mountain tea (Sideritis plants): A potential anti-atherogenic agent?

2021 ◽  
pp. 27-31
Author(s):  
Ekaterina-Michaela Tomou ◽  
Despina N. Perrea ◽  
Helen Skaltsa
Keyword(s):  
Cardiovascular Diseases ◽  
Medicinal Plants ◽  
Adjuvant Therapy ◽  
Common Cold ◽  
Chemical Compounds ◽  
Gastrointestinal Disorders ◽  
Bioactive Constituents ◽  
Pharmacological Activities ◽  
Agent Based ◽  
Traditional Remedy

Atherosclerosis consists the leading cause of cardiovascular diseases. Over the last years, medicinal plants are considered as efficient agents in the prevention and adjuvant therapy of atherosclerosis. Mountain tea (Sideritis plants) is used as traditional remedy against common cold and gastrointestinal disorders. Its beneficial properties are attributed to its rich bioactive constituents. Polyphenols exhibit a broad range of pharmacological activities such as antioxidant, anti-inflammatory and anti-atherosclerotic effects. The present review summarizes and discusses the potential of mountain tea as an anti-atherogenic agent based on its bioactive chemical compounds and their reported pharmacological activities.

scholarly journals TREATMENT OF VARIOUS DISEASES BY CANNA INDICA L. - A PROMISING HERB

2018 ◽  
Vol 11 (12) ◽  
pp. 51
Author(s):  
Vanita Kanase ◽  
Sunita Vishwakarma
Keyword(s):  
Chemical Constituents ◽  
Chemical Compounds ◽  
Phytochemical Analysis ◽  
Pharmacological Activities ◽  
Canna Indica ◽  
Whole Plant ◽  
Traditional Remedy ◽  
The Family ◽  
Pharmacological Studies ◽  
Human Use

In recent years, ethnobotanical and traditional application of natural compounds, principally of plant origin established much attention as they are well tested for their effectiveness and generally believed to be non-toxic for human use. Canna indica L. is a tropical herb belonging to the family Cannaceae. It has been extensively used in a traditional remedy for the treatment of many complaints. The phytochemical analysis of C. indica exhibited that it contained various phytochemicals including alkaloids, cardiac glycosides, anthocyanin pigments, flavonoids, steroids, terpenoids, tannins, phlobatannins, saponins, carbohydrates, proteins, oils, and many other chemical compounds. The pharmacological studies showed that this plant exerted anthelmintic, antibacterial, antimicrobial, antiviral, antidiabetic, antidiarrheal, anti-inflammatory, analgesic, immunomodulatory, antioxidant, cytotoxic, hemostatic, hepatoprotective, molluscicidal, and other effects. This review attempts to illuminate the available literature on C. indica (L.) with respect to ethnobotany, chemical constituents, and summary of numerous pharmacological activities. Every part of C. indica has valuable properties that can serve humanity so the whole plant can be broadly studied for further research aspects.

Phytochemistry and Pharmacology of Genus Bombax

2019 ◽  
Vol 9 (3) ◽  
pp. 184-196
Author(s):  
Deepshikha Rathore ◽  
Geetanjali ◽  
Ram Singh
Keyword(s):  
Medicinal Plants ◽  
Health Care Needs ◽  
Human Beings ◽  
Care Needs ◽  
Pharmacological Activities ◽  
Therapeutic Applications ◽  
Chemical Structures ◽  
Supportive Role ◽  
The Family ◽  
History Of

Background: The history of traditional systems of medicine goes parallel with the history of human beings. Even today people have faith in traditional systems of medicine based on medicinal plants to meet primary health care needs. Hence, the scientific evaluation and documentation of extracts and active ingredients of medicinal plants always play a supportive role in their medicinal applications. Objective: This review aims to present the phytochemicals isolated from the genus Bombax and their pharmacological applications. Methods: The literature from research and review papers was analyzed and the information was compiled to present the pharmacological applications of various secondary metabolites from genus Bombax. Results: The genus Bombax belongs to the family Malvaceae and known for its therapeutic applications. The crude, semi-purified and purified extracts of different parts of this plant have shown potential therapeutic applications. A total of 96 articles including research and review papers were referred for the compilation of isolated phytochemicals and their chemical structures. Conclusion: We systematically summarized 176 isolated compounds from the genus Bombax. The findings show that this plant shows potential towards pharmacological activities. The activities were found more from extracts than the single isolated compounds.

Anti-inflammatory Effects of Plant-based Foods and of their Constituents

2008 ◽  
Vol 78 (6) ◽  
pp. 293-298 ◽  
Author(s):  
Bernhard Watzl
Keyword(s):  
Cardiovascular Diseases ◽  
Bioactive Compounds ◽  
Pathological Condition ◽  
Wide Spectrum ◽  
Bioactive Constituents ◽  
Plant Foods ◽  
Whole Wheat ◽  
Markers Of Inflammation ◽  
Inflammatory Processes ◽  
Anti Inflammatory

Inflammation is a pathological condition underlying a number of diseases including cardiovascular diseases, cancer, and chronic inflammatory diseases. In addition, healthy, obese subjects also express markers of inflammation in their blood. Diet provides a variety of nutrients as well as non-nutritive bioactive constituents which modulate immunomodulatory and inflammatory processes. Epidemiological data suggest that dietary patterns strongly affect inflammatory processes. Primarily the intake of fruit and vegetables as well as of whole wheat is inversely associated with the risk of inflammation. In addition to observational studies there are also data from human intervention studies suggesting an anti-inflammatory potential of these plant foods. At the level of bioactive compounds occurring in plant foods, primarily carotenoids and flavonoids seem to modulate inflammatory as well as immunological processes. In conclusion, there is convincing evidence that plant foods and non-nutritive constituents associated with these foods modulate immunological and inflammatory processes. By means of anti-inflammatory activities a plant-based diet may contribute to the lower risk of cardiovascular diseases and cancer. A high intake of vegetables, fruit, and whole wheat as recommended by all international nutrition authorities provides a wide spectrum of bioactive compounds at health-promoting concentrations.

scholarly journals Increasing the Power of Polyphenols through Nanoencapsulation for Adjuvant Therapy against Cardiovascular Diseases

Molecules ◽  
2021 ◽  
Vol 26 (15) ◽  
pp. 4621
Author(s):  
Lucileno Rodrigues Trindade ◽  
Davi Vieira Teixeira da da Silva ◽  
Diego dos Santos Baião ◽  
Vania Margaret Flosi Paschoalin
Keyword(s):  
Clinical Trials ◽  
Cardiovascular Diseases ◽  
Adjuvant Therapy ◽  
Vascular Diseases ◽  
Ppar Γ ◽  
Epidemiological Surveys ◽  
Genes Encoding ◽  
And Oxidative Stress ◽  
Gradual Release ◽  
Inflammatory Action

Polyphenols play a therapeutic role in vascular diseases, acting in inherent illness-associate conditions such as inflammation, diabetes, dyslipidemia, hypertension, and oxidative stress, as demonstrated by clinical trials and epidemiological surveys. The main polyphenol cardioprotective mechanisms rely on increased nitric oxide, decreased asymmetric dimethylarginine levels, upregulation of genes encoding antioxidant enzymes via the Nrf2-ARE pathway and anti-inflammatory action through the redox-sensitive transcription factor NF-κB and PPAR-γ receptor. However, poor polyphenol bioavailability and extensive metabolization restrict their applicability. Polyphenols carried by nanoparticles circumvent these limitations providing controlled release and better solubility, chemical protection, and target achievement. Nano-encapsulate polyphenols loaded in food grade polymers and lipids appear to be safe, gaining resistance in the enteric route for intestinal absorption, in which the mucoadhesiveness ensures their increased uptake, achieving high systemic levels in non-metabolized forms. Nano-capsules confer a gradual release to these compounds, as well as longer half-lives and cell and whole organism permanence, reinforcing their effectiveness, as demonstrated in pre-clinical trials, enabling their application as an adjuvant therapy against cardiovascular diseases. Polyphenol entrapment in nanoparticles should be encouraged in nutraceutical manufacturing for the fortification of foods and beverages. This study discusses pre-clinical trials evaluating how nano-encapsulate polyphenols following oral administration can aid in cardiovascular performance.

A review of ancient medicinal plants utilized in therapy of cardiovascular diseases

2021 ◽  
Vol 8 (1) ◽  
pp. 1-4
Author(s):  
Jayalalita Shanakka Kamble ◽  
Nagalakshmi N C ◽  
Chaurasiya Raunakkumar ◽  
Usha Verma ◽  
Harshitha Arun Pardhe
Keyword(s):  
Cardiovascular Diseases ◽  
Medicinal Plants

scholarly journals CYTOTOXICITY ACTIVITY OF SOME INDIAN MEDICINAL PLANTS

2016 ◽  
Vol 8 (4) ◽  
pp. 86
Author(s):  
Dora Babu Neerugatti ◽  
Ganga Rao Battu ◽  
Raviteja Bandla
Keyword(s):  
Medicinal Plants ◽  
Cell Lines ◽  
Human Cancer ◽  
Bioactive Constituents ◽  
Cytotoxicity Activity ◽  
Human Cancer Cell Lines ◽  
Methanolic Extracts ◽  
Dose Dependent ◽  
New Anticancer Drugs ◽  
Indian Medicinal Plants

Objective: The current study is carried out to evaluate cytotoxicity activity of the methanolic extracts of some medicinal plants (Buchanania axillaris Desr, Tamilnadia ulignosa Retz, Phaseolus semierectus L and Stylosanthes fruticosa Retz).Methods: Cytotoxicity activity was evaluated on human cancer cell lines such as lung cancer (A549) and skin cancer (A431) using MTT assay method.Results: The selected plant extracts showed the dose-dependent cytotoxicity activity on the tested cell lines. The cytotoxicity variations on different cell lines were also observed for tested plants extracts. The cytotoxicity of the extracts was increased as the concentration of them was increased. Among all tested plants extracts Phaseolus semierectus showed the better cytotoxicity activity on tested cell lines.Conclusion: The results of the present study supported the folkloric usage of the studied plants and confirmed that the plant's extracts have the bioactive constituents with cytotoxic properties and their isolation can be useful for developing new anticancer drugs.

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