A comparative study on initial prothesis stability fixed by strontium-containing hydroxyapatite comparing with polymethyl methacrylate bone cement

2009 ◽  
Author(s):  
Ting Wang
Keyword(s):  
Comparative Study ◽  
Bone Cement ◽  
Polymethyl Methacrylate

The Comparative Study of Gelatin/CNT-contained Mg-Ca-P Bone Cement with the Plain and CNT-reinforced Ones

2021 ◽  
Vol 18 (3) ◽  
pp. 623-636
Author(s):  
Mohammad Hossein Esnaashary ◽  
Masoud Karfarma ◽  
Hamid Reza Rezaie ◽  
Alireza Khavandi ◽  
Jafar Javadpour
Keyword(s):  
Comparative Study ◽  
Bone Cement ◽  
The Comparative Study

N-acetyl cysteine prevents polymethyl methacrylate bone cement extract-induced cell death and functional suppression of rat primary osteoblasts

2010 ◽  
Vol 92A (1) ◽  
pp. 285-296 ◽  
Author(s):  
Hideki Aita ◽  
Naoki Tsukimura ◽  
Masahiro Yamada ◽  
Norio Hori ◽  
Katsutoshi Kubo ◽  
...  
Keyword(s):  
Cell Death ◽  
Bone Cement ◽  
Polymethyl Methacrylate ◽  
Acetyl Cysteine ◽  
Primary Osteoblasts

scholarly journals Experimental study of the antibacterial activity of the lytic Staphylococcus aureus bacteriophage ph20 and lytic Pseudomonas aeruginosa bacteriophage ph57 during modelling of its impregnation into poly(methylmetacrylate) orthopedic implants (bone cement)

2018 ◽  
Vol 73 (1) ◽  
pp. 59-68 ◽  
Author(s):  
A. G. Samokhin ◽  
Ju. N. Kozlova ◽  
D. V. Korneev ◽  
O. S. Taranov ◽  
E. A. Fedorov ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Bone Cement ◽  
Polymethyl Methacrylate ◽  
Bacterial Colonization ◽  
Experimental Studies ◽  
Orthopedic Implants ◽  
Polymerization Process ◽  
Polymerization Reaction ◽  
Chemical Components

Background: The problem of bacterial colonization of implants used in medical practice continues to be relevant regardless of the material of the implant. Particular attention deserves polymeric implants, which are prepared ex tempore from polymethyl methacrylate, for example - duting orthopedic surgical interventions (so-called "bone cement"). The protection of such implants by antibiotic impregnation is subjected to multiple criticisms, therefore, as an alternative to antibiotics, lytic bacteriophages with a number of unique advantages can be used - however, no experimental studies have been published on the possibility of impregnating bacteriophages into polymethyl methacrylate and their antibacterial activity assessment under such conditions.Aims: to evaluate the possibility of physical placement of bacteriophages in polymethylmethacrylate and to characterize the lytic antibacterial effect of two different strains of bacteriophages when impregnated into polymer carrier ex tempore during the polymerization process in in vitro model.Materials and methods:  First stage - Atomic force microscopy (AFM) of polymethyl methacrylate samples for medical purposes was used to determine the presence and size of caverns in polymethyl methacrylate after completion of its polymerization at various reaction  temperatures (+6…+25°C and +18…+50°C).The second stage was performed in vitro and included an impregnation of two different bacteriophage strains (phage ph20 active against S. aureus and ph57 active against Ps. aeruginosa) into polymethyl methacrylate during the polymerization process, followed by determination of their antibacterial activity.Results: ACM showed the possibility of bacteriophages placement in the cavities of polymethyl methacrylate - the median of the section and the depth of cavities on the outer surface of the polymer sample polymerized at +18…+50°C were 100.0 and 40.0 nm, respectively, and on the surface of the transverse cleavage of the sample - 120.0 and 100.0 nm, respectively, which statistically did not differ from the geometric dimensions of the caverns of the sample polymerized at a temperature of +6…+25°C.The study of antibacterial activity showed that the ph20 bacteriophage impregnated in polymethyl methacrylate at +6…+25°C lost its effective titer within the first six days after the start of the experiment, while the phage ph57 retained an effective titer for at least 13 days.Conclusion: the study confirmed the possibility of bacteriophages impregnation into medical grade polymethyl methacrylate, maintaining the effective titer of the bacteriophage during phage emission into the external environment, which opens the way for the possible application of this method of bacteriophage delivery in clinical practice. It is also assumed that certain bacteriophages are susceptible to aggressive influences from the chemical components of "bone cement" and / or polymerization reaction products, which requires strict selection of bacteriophage strains that could be suitable for this method of delivery.

scholarly journals Comparative Study of Antibiotic Elution Profiles From Alternative Formulations of Polymethylmethacrylate Bone Cement

2019 ◽  
Vol 34 (7) ◽  
pp. 1458-1461 ◽  
Author(s):  
Daniel G. Meeker ◽  
Kasa B. Cooper ◽  
Regis L. Renard ◽  
Simon C. Mears ◽  
Mark S. Smeltzer ◽  
...  
Keyword(s):  
Comparative Study ◽  
Bone Cement

Local antibiotic treatment of soft tissue and bone infections of the foot

1990 ◽  
Vol 80 (7) ◽  
pp. 345-353 ◽  
Author(s):  
DE Stabile ◽  
AM Jacobs
Keyword(s):  
Soft Tissue ◽  
Bone Cement ◽  
Success Rate ◽  
Polymethyl Methacrylate ◽  
Antibiotic Treatment ◽  
Soft Tissue Infection ◽  
Definitive Diagnosis ◽  
Histologic Examination ◽  
Bone Infections ◽  
Local Antibiotic

Twenty-seven pedal soft tissue and bone infections in 26 patients were treated with surgical necrectomy of infected tissues and implantation of antibiotic-loaded polymethyl methacrylate bone cement beads on chains. The definitive diagnosis of the infected tissues was obtained by culture and histologic examination in all of the cases. A wide variety of foot infections was successfully treated in this manner. The success rate without recurrence of osteomyelitis or soft tissue infection was 95% in this study at an average of 16 months after surgery.

Effect of MWCNT addition on the thermal and rheological properties of polymethyl methacrylate bone cement

Carbon ◽  
2011 ◽  
Vol 49 (9) ◽  
pp. 2893-2904 ◽  
Author(s):  
Ross Ormsby ◽  
Tony McNally ◽  
Christina Mitchell ◽  
Peter Halley ◽  
Darren Martin ◽  
...  
Keyword(s):  
Bone Cement ◽  
Rheological Properties ◽  
Polymethyl Methacrylate
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