The cost effectiveness of neoral¡ (cyslosporine) versus tacrolimus based immunosuppressive regimen in Chinese cadaveric renal transplant recipients : a paired kidney analysis

2009 ◽  
Author(s):  
Yan-lun, Allen Liu
Keyword(s):  
Cost Effectiveness ◽  
Renal Transplant ◽  
Immunosuppressive Regimen ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Cadaveric Renal Transplant ◽  
The Cost

scholarly journals Modelling the Cost-Effectiveness of Implementing a Dietary Intervention in Renal Transplant Recipients

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1175
Author(s):  
Friso B. Coerts ◽  
Judith J. Gout-Zwart ◽  
Eke G. Gruppen ◽  
Yvonne van der Veen ◽  
Maarten J. Postma ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Renal Transplant ◽  
The Netherlands ◽  
Budget Impact ◽  
Dietary Adherence ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Risk Of Death ◽  
Potassium Supplementation ◽  
The Cost

Background: The Dietary Approach to Stop Hypertension (DASH) and potassium supplementation have been shown to reduce the risk of death with a functioning graft (DWFG) and renal graft failure in renal transplant recipients (RTR). Unfortunately, a key problem for patients is the adherence to these diets. The aim of this study is to evaluate the cost-effectiveness and budget impact of higher adherence to either the DASH or potassium supplementation. Methods: A Markov model was used to simulate the life course of 1000 RTR in the Netherlands. A societal perspective with a lifetime time horizon was used. The potential effect of improvement of dietary adherence was modelled in different scenarios. The primary outcomes are the incremental cost-effectiveness ratio (ICER) and the budget impact. Results: In the base case, improved adherence to the DASH diet saved 27,934,786 and gained 1880 quality-adjusted life years (QALYs). Improved adherence to potassium supplementation saved €1,217,803 and gained 2901 QALYs. Both resulted in dominant ICERs. The budget impact over a five-year period for the entire Dutch RTR population was €8,144,693. Conclusion: Improving dietary adherence in RTR is likely to be cost-saving and highly likely to be cost-effective compared to the current standard of care in the Netherlands.

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