Bone mass in Chinese women around the menopause : the role of estrogen receptor beta gene polymorphisms and environmental risk factors

2006 ◽  
Author(s):  
Jing Gu
Keyword(s):  
Risk Factors ◽  
Estrogen Receptor ◽  
Bone Mass ◽  
Environmental Risk ◽  
Gene Polymorphisms ◽  
Chinese Women ◽  
Estrogen Receptor Beta ◽  
Beta Gene ◽  
Receptor Beta

scholarly journals Status of Estrogen Receptor Beta Gene Polymorphisms rs1256049 and rs4986938 in a cohort of South Indian women with Primary ovarian insufficiency

2021 ◽  
Vol 12 (1) ◽  
pp. 357-365
Author(s):  
Chaitany Sravanthi chillara ◽  
Aaji Pasha Shek ◽  
Madan Mohan V ◽  
Anuradha ◽  
Sujatha Madireddi
Keyword(s):  
Estrogen Receptor ◽  
Gene Polymorphisms ◽  
Estrogen Receptor Beta ◽  
Primary Ovarian Insufficiency ◽  
Premature Ovarian Insufficiency ◽  
Ovarian Insufficiency ◽  
Indian Women ◽  
South Indian ◽  
Beta Gene ◽  
Receptor Beta

The current study is aimed to investigate the role of estrogen receptor beta gene polymorphisms for causation of Primary Ovarian insufficiency (POI) in south Indian women. Primary Ovarian insufficiency (POI) is a menstrual disorder presenting with Primary and secondary amenorrhea, decreased estradiol levels and increased gonadotrophin levels. Most cases of POI remain unresolved even after exhaustive investigations and is a significant cause of infertility in women in the reproductive age. In this study a total of 276 subjects, of which 138 POI patients and 138 controls were analysed for biochemical profiles of FSH, LH and Estradiol. Genotypic frequencies were calculated for different models of the SNP rs1256049 and rs4986938 in the  Estrogen receptor Beta gene by PCR-RFLP (Restriction length polymorphism) analysis. Statistically, significant relation is found for FSH, LH and Estradiol profiles of a different group of Premature ovarian insufficiency and controls (p<0.0001). Genotypic frequencies between patients and controls were compared, and strength of the interdependence of genotypes and POI is confirmed by the odds ratio and 95% confidence intervals.  Incidence of 1082 G>A (rs1256049) polymorphisms and 1730 G>A (rs4986938) were not significantly different in both patient and control group (P=0.21 and P=0.4). The presence of 1082 G>A (rs1256049) polymorphisms and 1730 G>A (rs4986938) is not associated with causation of Premature ovarian insufficiency in south Indian women.

scholarly journals The role of estrogen receptor-beta gene +1730G/A polymorphisms in recurrent pregnancy loss

Medicine ◽  
2021 ◽  
Vol 100 (7) ◽  
pp. e24398
Author(s):  
Fangxiang Mu ◽  
Minge Shi ◽  
Li Huang ◽  
Dafen Wang ◽  
Aiqun Shen
Keyword(s):  
Estrogen Receptor ◽  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Estrogen Receptor Beta ◽  
Beta Gene ◽  
Receptor Beta

scholarly journals Given breast cancer, is fat better than thin? Impact of the estrogen receptor beta gene polymorphisms

2012 ◽  
Vol 137 (3) ◽  
pp. 849-862 ◽  
Author(s):  
Signe Borgquist ◽  
Maria Hjertberg ◽  
Maria Henningson ◽  
Christian Ingvar ◽  
Carsten Rose ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Gene Polymorphisms ◽  
Estrogen Receptor Beta ◽  
Beta Gene ◽  
Receptor Beta ◽  
Better Than

scholarly journals Correction: Potential Role of Estrogen Receptor Beta as a Tumor Suppressor of Epithelial Ovarian Cancer

PLoS ONE ◽  
2013 ◽  
Vol 8 (5) ◽  
Author(s):  
Carine Bossard ◽  
Muriel Busson ◽  
David Vindrieux ◽  
Françoise Gaudin ◽  
Véronique Machelon ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Estrogen Receptor ◽  
Tumor Suppressor ◽  
Epithelial Ovarian Cancer ◽  
Potential Role ◽  
Estrogen Receptor Beta ◽  
Receptor Beta ◽  
Correction Potential

Estrogen Receptor-beta Gene Polymorphism Affects Cardiorespiratory Fitness In Japanese Women

2015 ◽  
Vol 47 ◽  
pp. 80
Author(s):  
Koichiro Hayashi ◽  
Motoyuki Iemitsu ◽  
Haruka Murakami ◽  
Kiyoshi Sanada ◽  
Yuko Gando ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Gene Polymorphism ◽  
Cardiorespiratory Fitness ◽  
Estrogen Receptor Beta ◽  
Japanese Women ◽  
Beta Gene ◽  
Receptor Beta

Polymorphisms in the Estrogen Receptor Beta Gene and Risk of Breast Cancer: No Association

2003 ◽  
Vol 79 (3) ◽  
pp. 409-413 ◽  
Author(s):  
Asta Försti ◽  
Chunyan Zhao ◽  
Elisabeth Israelsson ◽  
Karin Dahlman-Wright ◽  
Jan-Åke Gustafsson ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Estrogen Receptor Beta ◽  
Beta Gene ◽  
Receptor Beta
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