Correlation of estrogen receptor beta gene polymorphisms with spinal bone mineral density in peri- and post-menopausal Greek women

Maturitas ◽  
2006 ◽  
Vol 53 (4) ◽  
pp. 380-385 ◽  
Author(s):  
Z. Efstathiadou ◽  
G. Koukoulis ◽  
N. Stakias ◽  
A. Challa ◽  
E. Zintzaras ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Estrogen Receptor ◽  
Bone Mineral ◽  
Gene Polymorphisms ◽  
Estrogen Receptor Beta ◽  
Spinal Bone Mineral Density ◽  
Mineral Density ◽  
Post Menopausal ◽  
Beta Gene ◽  
Receptor Beta

T-1213C polymorphism of estrogen receptor beta is associated with low bone mineral density and osteoporotic fractures

Bone ◽  
2006 ◽  
Vol 39 (5) ◽  
pp. 1097-1106 ◽  
Author(s):  
Annie W.C. Kung ◽  
Billy M.H. Lai ◽  
Mandy Y.M. Ng ◽  
Vivian Chan ◽  
Pak C. Sham
Keyword(s):  
Bone Mineral Density ◽  
Estrogen Receptor ◽  
Bone Mineral ◽  
Estrogen Receptor Beta ◽  
Osteoporotic Fractures ◽  
Mineral Density ◽  
Low Bone Mineral Density ◽  
Receptor Beta

Estrogen Receptor α Gene Polymorphisms and Bone Mineral Density in Healthy Children and Young Adults

2004 ◽  
Vol 74 (6) ◽  
pp. 495-500 ◽  
Author(s):  
A. M. Boot ◽  
I. M. van der Sluis ◽  
S. M. P. F. de Muinck Keizer-Schrama ◽  
J. B. J. van Meurs ◽  
E. P. Krenning ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Estrogen Receptor ◽  
Young Adults ◽  
Bone Mineral ◽  
Gene Polymorphisms ◽  
Estrogen Receptor Α ◽  
Healthy Children ◽  
Mineral Density ◽  
Children And Young Adults ◽  
Estrogen Receptor Α Gene

scholarly journals Status of Estrogen Receptor Beta Gene Polymorphisms rs1256049 and rs4986938 in a cohort of South Indian women with Primary ovarian insufficiency

2021 ◽  
Vol 12 (1) ◽  
pp. 357-365
Author(s):  
Chaitany Sravanthi chillara ◽  
Aaji Pasha Shek ◽  
Madan Mohan V ◽  
Anuradha ◽  
Sujatha Madireddi
Keyword(s):  
Estrogen Receptor ◽  
Gene Polymorphisms ◽  
Estrogen Receptor Beta ◽  
Primary Ovarian Insufficiency ◽  
Premature Ovarian Insufficiency ◽  
Ovarian Insufficiency ◽  
Indian Women ◽  
South Indian ◽  
Beta Gene ◽  
Receptor Beta

The current study is aimed to investigate the role of estrogen receptor beta gene polymorphisms for causation of Primary Ovarian insufficiency (POI) in south Indian women. Primary Ovarian insufficiency (POI) is a menstrual disorder presenting with Primary and secondary amenorrhea, decreased estradiol levels and increased gonadotrophin levels. Most cases of POI remain unresolved even after exhaustive investigations and is a significant cause of infertility in women in the reproductive age. In this study a total of 276 subjects, of which 138 POI patients and 138 controls were analysed for biochemical profiles of FSH, LH and Estradiol. Genotypic frequencies were calculated for different models of the SNP rs1256049 and rs4986938 in the  Estrogen receptor Beta gene by PCR-RFLP (Restriction length polymorphism) analysis. Statistically, significant relation is found for FSH, LH and Estradiol profiles of a different group of Premature ovarian insufficiency and controls (p<0.0001). Genotypic frequencies between patients and controls were compared, and strength of the interdependence of genotypes and POI is confirmed by the odds ratio and 95% confidence intervals.  Incidence of 1082 G>A (rs1256049) polymorphisms and 1730 G>A (rs4986938) were not significantly different in both patient and control group (P=0.21 and P=0.4). The presence of 1082 G>A (rs1256049) polymorphisms and 1730 G>A (rs4986938) is not associated with causation of Premature ovarian insufficiency in south Indian women.

The Association of Bone Mineral Density with Estrogen Receptor Gene Polymorphisms

2006 ◽  
Vol 119 (9) ◽  
pp. S79-S86 ◽  
Author(s):  
Gail A. Greendale ◽  
Jian Chu ◽  
Robert Ferrell ◽  
John F. Randolph ◽  
Janet M. Johnston ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Estrogen Receptor ◽  
Bone Mineral ◽  
Gene Polymorphisms ◽  
Receptor Gene ◽  
Estrogen Receptor Gene ◽  
Mineral Density ◽  
Receptor Gene Polymorphisms
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