scholarly journals Effects of Eccentric Exercise on Skeletal Muscle Injury: From An Ultrastructure Aspect: A Review

2021 ◽  
Vol 5 (1) ◽  
pp. 15-20
Author(s):  
Jianhua Ying ◽  
Xuanzhen Cen ◽  
Peimin Yu
Keyword(s):  
Skeletal Muscle ◽  
Eccentric Exercise ◽  
Muscle Injury ◽  
Skeletal Muscle Injury

scholarly journals MRI Quantitative Analysis of Eccentric Exercise-induced Skeletal Muscle Injury in Rats

2020 ◽  
Vol 27 (4) ◽  
pp. e72-e79 ◽  
Author(s):  
Congcong Fu ◽  
Yu Xia ◽  
Fan Meng ◽  
Fei Li ◽  
Qiang Liu ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Quantitative Analysis ◽  
Eccentric Exercise ◽  
Muscle Injury ◽  
Skeletal Muscle Injury ◽  
Exercise Induced

Astaxanthin Supplementation Does Not Attenuate Muscle Injury Following Eccentric Exercise in Resistance-Trained Men

2005 ◽  
Vol 15 (4) ◽  
pp. 401-412 ◽  
Author(s):  
Richard J. Bloomer ◽  
Andrew Fry ◽  
Brian Schilling ◽  
Loren Chiu ◽  
Naruhiro Hori ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Eccentric Exercise ◽  
Muscle Injury ◽  
Muscle Performance ◽  
Safflower Oil ◽  
Similar Response ◽  
Post Exercise ◽  
Skeletal Muscle Injury ◽  
Treatment Groups ◽  
Exercise Muscle

This investigation was designed to determine the effects of astaxanthin on markers of skeletal muscle injury. Twenty resistance trained men (mean ± standard error of the mean: age, 25.1 ± 1.6 y; height, 1.79 ± 0.02 m; weight, 86.8 ± 4.4 kg) were assigned to either a placebo (1732 mg safflower oil, n = 10) or astaxanthin (BioAstin; 1732 mg safflower oil; haematococcus algae extract [contains 4 mg astaxanthin and 480 mg lutein], n = 10). Subjects consumed their assigned treatment for 3 wk prior to eccentric exercise (10 sets of 10 repetitions at 85% of one repetition maximum) and through 96 h post-exercise. Muscle soreness, creatine kinase (CK), and muscle performance was measured before and through 96 h post-exercise. A similar response was observed for both treatment groups for all dependent variables, indicating that in resistance trained men, astaxanthin supplementation does not favorably affect indirect markers of skeletal muscle injury following eccentric loading.

scholarly journals Does high muscle temperature accentuate skeletal muscle injury from eccentric exercise?

2016 ◽  
Vol 4 (9) ◽  
pp. e12777 ◽  
Author(s):  
John W. Castellani ◽  
Edward J. Zambraski ◽  
Michael N. Sawka ◽  
Maria L. Urso
Keyword(s):  
Skeletal Muscle ◽  
Eccentric Exercise ◽  
Muscle Injury ◽  
Muscle Temperature ◽  
Skeletal Muscle Injury

scholarly journals Adenosine A3 receptor stimulation induces protection of skeletal muscle from eccentric exercise-mediated injury

2010 ◽  
Vol 299 (1) ◽  
pp. R259-R267 ◽  
Author(s):  
Ruibo Wang ◽  
Maria L. Urso ◽  
Edward J. Zambraski ◽  
Erik P. Rader ◽  
Kevin P. Campbell ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Eccentric Exercise ◽  
Receptor Agonist ◽  
Muscle Injury ◽  
Protective Role ◽  
Blue Dye ◽  
Receptor Stimulation ◽  
Skeletal Muscle Injury ◽  
Exercise Induced ◽  
Dystrophic Mice

Effective therapy to reduce skeletal muscle injury associated with severe or eccentric exercise is needed. The purpose of this study was to determine whether adenosine receptor stimulation can mediate protection from eccentric exercise-induced muscle injury. Downhill treadmill exercise (−15°) was used to induce eccentric exercise-mediated skeletal muscle injury. Experiments were conducted in both normal wild-type (WT) mice and also in β-sarcoglycan knockout dystrophic mice, animals that show an exaggerated muscle damage with the stress of exercise. In the vehicle-treated WT animals, eccentric exercise increased serum creatine kinase (CK) greater than 3-fold to 358.9 ± 62.7 U/l (SE). This increase was totally abolished by stimulation of the A3 receptor. In the dystrophic β-sarcoglycan-null mice, eccentric exercise caused CK levels to reach 55,124 ± 5,558 U/l. A3 receptor stimulation in these animals reduced the CK response by nearly 50%. In the dystrophic mice at rest, 10% of the fibers were found to be damaged, as indicated by Evans blue dye staining. While this percentage was doubled after exercise, A3 receptor stimulation eliminated this increase. Neither the A1 receptor agonist 2-chloro- N6-cyclopentyladenosine (0.05 mg/kg) nor the A2A receptor agonist 2- p-(2-carboxyethyl)phenethylamino-5′- N-ethylcarboxamidoadenosine (0.07 mg/kg) protected skeletal muscle from eccentric exercise injury in WT or dystrophic mice. The protective effect of adenosine A3 receptor stimulation was absent in mice, in which genes for phospholipase C β2/β3 (PLCβ2/β3) and β-sarcoglycan were deleted. The present study elucidates a new protective role of the A3 receptor and PLCβ2/β3 and points to a potentially effective therapeutic strategy for eccentric exercise-induced skeletal muscle injury.

scholarly journals Isokinetic eccentric exercise can induce skeletal muscle injury within the physiologic excursion of muscle-tendon unit: a rabbit model

2007 ◽  
Vol 2 (1) ◽  
pp. 13 ◽  
Author(s):  
Yang-Hwei Tsuang ◽  
Shui-Ling Lam ◽  
Lien-Chen Wu ◽  
Chang-Jung Chiang ◽  
Li-Ting Chen ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Eccentric Exercise ◽  
Muscle Injury ◽  
Rabbit Model ◽  
Skeletal Muscle Injury

scholarly journals Stem Cells for the Treatment of Skeletal Muscle Injury

2009 ◽  
Vol 28 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Andres J. Quintero ◽  
Vonda J. Wright ◽  
Freddie H. Fu ◽  
Johnny Huard
Keyword(s):  
Skeletal Muscle ◽  
Stem Cells ◽  
Muscle Injury ◽  
Skeletal Muscle Injury
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