scholarly journals Subperiosteal Orbital Hematoma: Imaging Findings of a Rare Complication of Sickle Cell Disease

2019 ◽  
Vol 103 (1) ◽  
Author(s):  
Nick Van de Voorde ◽  
Paul M. Parizel ◽  
Sven Dekeyzer
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Rare Complication ◽  
Imaging Findings ◽  
Cell Disease ◽  
Orbital Hematoma

Cranial epidural hematomas: A case series and literature review of this rare complication associated with sickle cell disease

2016 ◽  
Vol 64 (3) ◽  
pp. e26237 ◽  
Author(s):  
Jennifer Hamm ◽  
Nisha Rathore ◽  
Pearlene Lee ◽  
Zachary LeBlanc ◽  
Jeffrey Lebensburger ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Literature Review ◽  
Sickle Cell ◽  
Rare Complication ◽  
Case Series ◽  
Cell Disease

Acute Hepatic Sequestration Crisis: A Rare Complication of Sickle Cell Disease

2010 ◽  
Vol 105 ◽  
pp. S289-S290
Author(s):  
Bradford Whitmer ◽  
Fernando Gamarra ◽  
Laurence Stawick
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Rare Complication ◽  
Cell Disease

scholarly journals Clinical and laboratory parameters, risk factors predisposing to the development of priapism in sickle cell patients

2019 ◽  
Vol 245 (1) ◽  
pp. 79-83
Author(s):  
Salam Alkindi ◽  
Said S Almufargi ◽  
Anil Pathare
Keyword(s):  
Risk Factors ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Cardiovascular Response ◽  
Rare Complication ◽  
Acute Chest Syndrome ◽  
Mean Corpuscular Hemoglobin ◽  
Cell Disease ◽  
Laboratory Parameters ◽  
Blood Exchange

Although sickle cell disease is very common in Oman, priapism is a relatively rare complication of this disease. This study was aimed to identify the clinical and laboratory risk factors that predispose sickle cell disease patients to priapism. In a retrospective, case-control study, data on 21 male sickle cell disease patients, with priapism, were compared to 20 age and sex-matched sickle cell disease patients without priapism from the hospital medical records. Specifically, the demographical, hematological, biochemical, and clinical parameters including complications attributable to priapism were studied. Means for continuous measures and independent t-test were used to evaluate the association between the parameter studied and the occurrence of priapism. Priapism occurrence was associated with low basal hemoglobin (Hb), along with an increase in other parameters such as white blood cell count (WBC) ( P = 0.010), platelet count ( P = 0.001), reticulocyte count ( P < 0.001), mean corpuscular volume (MCV) ( P < 0.001), and mean corpuscular hemoglobin (MCH) ( P < 0.001). Biochemical laboratory parameters revealed an association with an increased total bilirubin ( P < 0.001). Patients with priapism were more likely to have acute chest syndrome, stroke, pulmonary hypertension, asplenia ( P = 0.006), gallbladder stones, and consequently cholecystectomy. Blood exchange and Penile aspiration were the most frequent medical therapies ( P = 0.010 and P < 0.001 respectively). Patients with sickle cell disease who presented with priapism were young adults with low Hb, high WBC’s, platelets, reticulocytes, MCV, MCH, bilirubin, and LDH. These findings suggest an association of priapism with increased hemolysis. Impact statement Sickle cell disease is prevalent throughout the world with a 5.8% incidence of sickle cell trait among the Omani population, yet priapism was a relatively rare complication. Penile erection and detumescence are complex physiological processes, which require a delicate neurohormonal and cardiovascular response. In this cohort, young SCD patients developed priapism with a low incidence of complications. These patients had high WBCs, platelets, bilirubin, LDH, and reticulocytes with low hemoglobin as compared to controls, suggesting an increased hemolytic process. Favorable outcome was dependent on early intervention, with almost half of these patients needing surgical intervention.

scholarly journals Major Artery Occlusion: a Rare Complication of Sickle Cell Disease

1970 ◽  
Vol 2 (1) ◽  
pp. e2010007
Author(s):  
Adnan Agha
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Internal Carotid ◽  
Rare Complication ◽  
Artery Occlusion ◽  
Left Internal Carotid Artery ◽  
Cell Disease ◽  
Vessel Occlusion ◽  
Major Vessel ◽  
Haemolytic Anemia

Abstract: Sickle cell disease is hereditary hemoglobinopathy which causes haemolytic anemia, vaso-occlusive crisis, ischemic injuries and many other morbidities like cerebral infarction.  In this report, we describe a case of a young patient with sickle cell disease presenting with right-sided weakness and slurring of speech with examination confirming right-sided hemiparesis with motor aphasia. On further investigation, she was found to have frontotemporal infarction.  On magnetic resonance imaging with angiography, she was found to have absent circulation in left internal carotid artery probably secondary to sickle cell disease.  Major vessel occlusion is rare complication of sickle cell disease that one must bear in mind.

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