scholarly journals The Role Of Diffusion-Weighted Mr Imaging And Adc Values In The Diagnosis Of Gastric Tumors

2012 ◽  
Vol 95 (1) ◽  
pp. 1 ◽  
Author(s):  
S Avcu ◽  
H Arslan ◽  
O Unal ◽  
C Kotan ◽  
M Izmirli
2012 ◽  
Vol 95 (5) ◽  
pp. 334
Author(s):  
G Ceulemans ◽  
H Everaert ◽  
D Verdries ◽  
T Lahoutte ◽  
B Ilsen

Author(s):  
Preeti Mundhada ◽  
Sudarshan Rawat ◽  
Ullas Acharya ◽  
Dhananjay Raje

Abstract Aim To determine the role of diffusion-weighted imaging (DWI) with apparent diffusion coefficient (ADC) values in differentiating benign and malignant orbital masses. Materials and Methods After obtaining institutional ethical board approval and informed consent from all patients, an observational study was done for a period of 24 months in the radiology department of a tertiary care hospital in South India. Conventional magnetic resonance imaging and DWI using a 3T scanner was done for all patients with suspected orbital mass lesion. ADC value and clinicohistopathological correlation were studied for every patient. Chi-square test was used to compare the signal characteristics of DWI and ADC maps between benign and malignant lesions. A comparison of mean ADC values for benign and malignant masses was performed using Student’s t-test for independent samples. The cut-off value for ADC was obtained using the receiver operating characteristic (ROC) curve. Results Of 44 patients with orbital lesions, 70% were benign and 30% were malignant. There was a significant difference in the mean ADC values of benign and malignant orbital masses. Using ROC curve analysis, an optimal ADC threshold of 1.26 × 10−3 mm2/s was calculated for the prediction of malignancy with 100% sensitivity, 80.65% specificity, and 86.36% accuracy (95% confidence interval: 0.872, 1.00, p < 0.0001). Two ADC thresholds were used to characterize the orbital masses with more than 90% confidence. Conclusion Quantitative assessment of ADC is a useful noninvasive diagnostic tool for differentiating benign and malignant orbital masses. Malignant orbital lesions demonstrate significantly lower ADC values as compared with benign lesions.


2003 ◽  
Vol 16 (2) ◽  
pp. 263-266
Author(s):  
F.G. Garaci ◽  
R. Floris ◽  
G. Manenti ◽  
L.M. Fantozzi ◽  
A. Bozzao

The aim of the present study was to assess the presence of changes in diffusivity in the brains of patients with tuberous sclerosis (TS) in areas free from signal alterations on conventional MR sequences. Ten patients and controls were evaluated. ROI were placed on ADC maps in the white matter (frontal, parietal and centrum semiovale) excluding areas with signal alterations on FLAIR images. ADC values of supratentorial white matter turned out to be higher than controls (P < .0001). Our data indicate that TS is more widely diffused than expected in the brains of affected patients.


2016 ◽  
Vol 85 (5) ◽  
pp. 943-949 ◽  
Author(s):  
Kazuhiro Kitajima ◽  
Toshiko Yamano ◽  
Kazuhito Fukushima ◽  
Yasuo Miyoshi ◽  
Seiichi Hirota ◽  
...  

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Hanan Mohammed Hanafy ◽  
Ayman Mohammed Ibrahim ◽  
Haytham Mohamed Nasser ◽  
Moataz Metwally Elsayed

Abstract Purpose of this study is: To evaluate the role of diffusion weighted magnetic resonance imaging in differentiation between malignant & benign hepatic focal lesions. Methods The study included 38 patients all of them were with hepatic focal lesions detected by ultrasound (between 20 and 85 years of age) referred from GIT and oncology departments. Each patient included in the study was subjected to full history taking, ultrasonography and conventional MRI sequences, post Gd- DTPA dynamic and Diffusion Weighted imaging as well as ADC value measurement. Technique was performed using a standard 1.5 Tesla unit (Ingenia, Philips). Detailed MRI and laboratory investigations were done. Results The study showed significant results were obtained between ADC values of benign and malignant hepatic focal lesions (p &lt; 0.001). Conclusion We concluded in this study according to the obtained results that DWI sequence together with quantitative ADC values should be used as an essential sequence to supplement the conventional MRI sequences for proper detection and characterization of hepatic focal lesions.


2016 ◽  
Vol 47 (4) ◽  
pp. 1689-1700 ◽  
Author(s):  
Donia M. Sobh ◽  
Galal El Sayed Magdy El Hawary ◽  
Mohamed Abou El Ghar ◽  
Tarek Abd El Moneim El-Diasty ◽  
Magdy El-Sayed Settein ◽  
...  

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