scholarly journals The Global Burden of Disease Study Estimates of Brazil’s Cervical Cancer Burden

2020 ◽  
Vol 86 (1) ◽  
Author(s):  
Nathalia V. S. Reis ◽  
Brenda B. Andrade ◽  
Maximiliano R. Guerra ◽  
Maria Tereza B. Teixeira ◽  
Deborah C. Malta ◽  
...  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xingxing Zhang ◽  
Qingle Zeng ◽  
Wenwen Cai ◽  
Weiqing Ruan

Abstract Background Cervical cancer is an important global health problem. In this study we aimed to analyze trends in cervical cancer at the global, regional, and national levels from 1990 to 2019, to inform health service decision-making. Methods Data on cervical cancer was extracted from the Global Burden of Disease study, 2019. Trends in cervical cancer burden were assessed based on estimated annual percentage change (EAPC) and age-standardized rate (ASR). Results Globally, decreasing trends were observed in incidence, death, and disability adjusted life years (DALYs) of cervical cancer from 1990 to 2019, with respective EAPCs of − 0.38 (95% confidence interval [CI]: − 0.41 to − 0.34), − 0.93 (95%CI: − 0.98 to − 0.88), and − 0.95 (95 CI%: − 1.00 to − 0.90). Meanwhile, decreasing trends were detected in most sociodemographic index (SDI) areas and geographic regions, particularly death and DALYs in Central Latin America, with respective EAPCs of − 2.61 (95% CI: − 2.76 to − 2.46) and − 2.48 (95% CI: − 2.63 to − 2.32); hhowever, a pronounced increasing trend in incidence occurred in East Asia (EAPC = 1.33; 95% CI: 1.12 to 1.55). At the national level, decreasing trends in cervical cancer were observed in most countries/territories, particularly DALYs in the Maldives (EAPC = − 5.06; 95% CI: − 5.40 to − 4.72), Whereas increasing trends were detected in Lesotho, Zimbabwe, and Bulgaria. Conclusions Slowly decreasing trends in cervical cancer were detected worldwide from 1990 to 2019. Cervical cancer remains a substantial health problem for women globally, requiring more effective prevention and control strategies.


2021 ◽  
Author(s):  
Xingxing Zhang ◽  
Danfeng Yu ◽  
Wenwen Cai ◽  
Weiqing Ruan

Abstract Background Cervical cancer remains an important global health problem. This article aims to analysis the trend of cervical cancer at global, regional, and national level from 1990 to 2019, which would inform the health decision-making. Methods Data on cervical cancer was extracted from the Global Burden of Disease study 2019. The trends of cervical cancer burden were estimated using estimated annual percentage change (EAPC) and age-standardized rate (ASR). Results Globally, the decreasing trends in incidence, death, and disability adjusted life years (DALYs) of cervical cancer were observed worldwide from 1990 to 2019, with the respective EAPCs were − 0.38 (95% confidence interval [CI]: -0.41 to -0.34), -0.93 (95%CI: -0.98 to -0.88), and − 0.95 (95CI%: -1.00 to -0.90). Meanwhile, decreasing trends were also seen in most sociodemographic index (SDI) areas and geographic regions, particularly the trends of death and DALYs in Central Latin America, in which the respective EAPCs were − 2.61 (95%CI: -2.76 to -2.46) and − 2.48 (95%CI: -2.63 to -2.32). However, pronounced increasing trends occurred in the incidence in East Asia (EAPC = 1.33; 95%CI: 1.12 to 1.55). At the national level, the decreasing trends of cervical cancer were observed in most countries/territories, particularly the DALYs in Maldives (EAPC=-5.06; 95%CI: -5.40 to -4.72). Whereas increasing trend were seen in Lesotho, Zimbabwe, and Bulgaria. Conclusions Slowly decreasing trends of cervical cancer were demonstrated worldwide from 1990 to 2019. Cervical cancer remains a substantial health problem globally, which required the more effective prevention and control strategies.


Author(s):  
Azin Nahvijou

Background: Cancer with 13% of all deaths is the third leading cause of mortality in Iran. We aimed to assess the burden of cancer in Iran by acquiring data from the Global Burden of Disease (GBD) study. Methods: This study was conducted on the DALY approach to examine the cancer burden in Iran from 1990 to 2016. A list of all cancers was extracted using the International Classification of Disease, tenth revision (ICD-10). Then, the cancer burden was assessed based on the type of cancer. The Percentage change (PC) by Daly’s number and age-standardized DALY rate (ASDR) was estimated. The cause of PC on the DALYs number from cancer was analyzed, and the share of every variable was determined. Results: In 2016, cancer caused 781.5 and 564 thousand DALYs for men and women, respectively. In all years, the DALYs number of cancer is higher in men than women. From 1990 to 2016, leukemia, stomach, tracheal, bronchus and lung (TBL) cancers were among the leading causes of cancer burden in Iran. The highest increase in PC of cancer DALYs from 1990 to 2016 happened by multiple myeloma with 302.4% and breast with 283.7%. The lowest increase occurred by Hodgkin lymphoma (-2.1%) and leukemia (18.2%). Conclusion: Cancers have grown more than doubled in terms of DALYs from 1990 to 2016. The majority of DALYs were due to Years of Life Lost, suggesting the need for prevention, early detection, and screening programs.


Liver Cancer ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 563-582 ◽  
Author(s):  
Longfei Lin ◽  
Lei Yan ◽  
Yuling Liu ◽  
Changhai Qu ◽  
Jian Ni ◽  
...  

Background: Liver cancer is one of the leading causes of cancer-related deaths worldwide. The primary causes of liver cancer include hepatitis B virus (HBV), hepatitis C virus (HCV), alcohol consumption, nonalcoholic fatty liver disease, and other factors. Aims: The objective of this study was to evaluate the global and sex-, age-, region-, country-, and etiology-related liver cancer burden, as well as the trends in liver cancer caused by different etiologies. Methods: The causes of liver cancer from 1990 to 2017, including global, regional, and national liver cancer incidence, mortality, and etiology, were collected from the Global Burden of Disease study 2017, and the time-dependent change in the trends of liver cancer burden was evaluated by annual percentage change. Results: The global liver cancer incidence and mortality have been increasing. There were 950,000 newly-diagnosed liver cancer cases and over 800,000 deaths in 2017, which is more than twice the numbers recorded in 1990. HBV and HCV are the major causes of liver cancer. HBV is the major risk factor of liver cancer in Asia, while HCV and alcohol abuse are the major risk factors in the high sociodemographic index and high human development index regions. The mean onset age and incidence of liver cancer with different etiologies have gradually increased in the past 30 years. Conclusions: The global incidence is still rising and the causes have national, regional, or population specificities. More targeted prevention strategies must be developed for the different etiologic types in order to reduce liver cancer burden.


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