Incidence and Mortality of Multiple Myeloma in China, 2006-2016: An Analysis of the Global Burden of Disease Study 2016

2019 ◽  
Author(s):  
Jiangmei Liu ◽  
Weiping Liu ◽  
Xinying Zeng ◽  
Jun Ma ◽  
Lijun Wang ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Burden Of Disease ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Incidence And Mortality ◽  
Disease Study

scholarly journals Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study

The Lancet ◽  
2020 ◽  
Vol 395 (10219) ◽  
pp. 200-211 ◽  
Author(s):  
Kristina E Rudd ◽  
Sarah Charlotte Johnson ◽  
Kareha M Agesa ◽  
Katya Anne Shackelford ◽  
Derrick Tsoi ◽  
...  
Keyword(s):  
Burden Of Disease ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Incidence And Mortality ◽  
Disease Study

scholarly journals Burden of Oral Cancer on the 10 Most Populous Countries from 1990 to 2019: Estimates from the Global Burden of Disease Study 2019

2022 ◽  
Vol 19 (2) ◽  
pp. 875
Author(s):  
Shu-Zhen Zhang ◽  
Long Xie ◽  
Zheng-Jun Shang
Keyword(s):  
United States ◽  
Oral Cancer ◽  
Burden Of Disease ◽  
The United States ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Life Years ◽  
Incidence And Mortality ◽  
Disease Study ◽  
Female Subjects

Background: Oral cancer (OC) is a common tumour that poses a threat to human health and imposes a heavy burden on countries. This study assessed the burden imposed by OC on the 10 most populous countries from 1990 to 2019 on the basis of gender, age and socio-demographic index. Methods: Data on incidence, mortality, disability-adjusted life years (DALY) and corresponding age-standardised rates (ASR) for OC in the 10 most populous countries from 1990 to 2019 were derived from the Global Burden of Disease Study 2019. Estimated annual percentage changes were calculated to assess the trends of morbidity, mortality and DALY. The indicator that served as a proxy for survival rate was the supplement of mortality-to-incidence ratio (SMIR) (1 − (M/I)). Results: The number of new cases, deaths and DALY have increased in all 10 countries in the past 30 years. Trends in age-standardised incidence rates (ASIR), age-standardised mortality rate (ASMR) and age-standardised DALY for OC in the 10 most populous countries varied. The SMIR increased in all countries, with most countries having an SMIR between 30% and 50%. In 2019, the United States had the highest SMIR at 76%, whereas Russia had the lowest at 21.7%. Incidence and mortality were close between male and female subjects in Japan, Indonesia, Mexico, India, Bangladesh and Pakistan. The incidence and mortality in male subjects in the United States, Russia, China and Brazil were two or more times those of female subjects. Gender difference was highest among patients aged 40–69 years. Conclusion: Trends and gender differences in ASIR, ASMR and age-standardised DALY for OC vary in the 10 most populous countries. Government cancer programs are often expensive to run, especially in countries with large populations. Policy makers need to take these differences into account when formulating policies.

scholarly journals Burden of Thyroid Cancer From 1990 to 2019 and Projections of Incidence and Mortality Until 2039 in China: Findings From Global Burden of Disease Study

2021 ◽  
Vol 12 ◽  
Author(s):  
Fang Cheng ◽  
Juan Xiao ◽  
Chunchun Shao ◽  
Fengyan Huang ◽  
Lihua Wang ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Burden Of Disease ◽  
Cohort Analysis ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Essential Information ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Incidence And Mortality ◽  
Disease Study

Projecting the burden of thyroid cancer (TC) over time provides essential information to effectively plan measures for its management and prevention. This research obtained data from the Global Burden of Disease (GBD) Study from between 1990 and 2019 to model how TC will affect China until 2039 by conducting the Bayesian age-period-cohort analysis. The number of new TC cases in China was 10,030 in 1990, 39,080 in 2019, and is projected to be 47,820 in 2039. This corresponds to 3,320, 7,240, and 4,160 deaths, respectively. Disability-adjusted life years (DALYs) cases increased from 103,490 in 1990 to 187,320 in 2019. The age-standardized rate (ASR) of incidence increased from 1.01 to 2.05 during 1990-2019 and was projected to increase to 3.37 per 100,000 person-years until 2039. The ASR of mortality (ASMR) remained stable during the study period and was projected to have a mild decline from 0.39 to 0.29/100,000 during 2020-2039. Although the ASMR in male patients has maintained increasing at a rate of 2.2% per year over the past 30 years, it is expected to decline at a rate of 1.07% per year in 2019-2039. The most significant increase in crude incidence occurred in people aged 45-65 from 1990 to 2019, however, this will shift into young people aged 10-24 from 2020 to 2039. In addition, the proportion of deaths and DALYs caused by obesity increased from 1990 to 2019 and affected men more than women. In conclusion, a substantial increase in counts of incidence of TC in China is projected over the next two decades, combined with the slightly declining mortality, indicating that rational health policies are needed in the future to cope with the increasing number of TC patients, especially among males and adolescents.

scholarly journals The global burden of nasopharyngeal carcinoma from 2009 to 2019: an observational study based on the Global Burden of Disease Study 2019

2021 ◽  
Author(s):  
Hao Yu ◽  
Xin Yin ◽  
Yiran Mao ◽  
Meiqin Chen ◽  
Qiuying Tang ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Incidence Rate ◽  
Burden Of Disease ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Mortality Trends ◽  
Life Years ◽  
Number Of Patients ◽  
Incidence And Mortality ◽  
Disease Study

Abstract Purpose The incidence and mortality rate of nasopharyngeal carcinoma (NPC) has changed in recent years. Our goal is to determine the epidemiological pattern of NPC to help policymakers allocate limited medical resources. Methods Detailed information about NPC from 2009 to 2019 was collected from the Global Burden of Disease 2019 database. Age-standardized rates (ASRs) and corresponding estimated annual percentage changes (EAPCs) were calculated to assess NPC’s incidence and mortality trends. Results Globally, there was a consistent increase in the NPC incidence cases from 2009 to 2019 (from 121.65 × 103 cases in 2009 to 176.50 × 103 cases in 2019, increasing by 45.09%). The age-standardized incidence rate (ASIR) of NPC increased from 1.81 in 2009 to 2.12 in 2019 (EAPC = 1.59, 95% CI 1.36–1.81). On the contrary, the mortality of NPC showed a downward trend (ASDR: 0.93 in 2009 and 0.86 in 2019; EAPC = − 0.63, 95% CI − 0.78 to − 0.48), and it was negatively correlated with the social demographic index (SDI) in most regions. Both incidence and mortality rates of high-incidence territories tended to be stable or decline. Males had significantly higher incidence and mortality of NPC than females. The number of patients with onset age greater than 50 years old accounted for the highest proportion. We found that smoking, occupational exposure to formaldehyde, and alcohol use were the main risk factors for NPC-related mortality. Conclusion Globally, the incidence rate of NPC has been slightly increasing, while the mortality and disability-adjusted life years (DALYs) have been decreasing. NPC burden in high-middle and middle SDI areas was the heaviest. The current prevention strategy should be repositioned, and some countries should formulate more targeted approaches to reduce the current burden of NPC.

scholarly journals The Burden and Trends of Primary Liver Cancer Caused by Specific Etiologies from 1990 to 2017 at the Global, Regional, National, Age, and Sex Level Results from the Global Burden of Disease Study 2017

Liver Cancer ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 563-582 ◽  
Author(s):  
Longfei Lin ◽  
Lei Yan ◽  
Yuling Liu ◽  
Changhai Qu ◽  
Jian Ni ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Cancer Incidence ◽  
Burden Of Disease ◽  
Primary Liver Cancer ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Targeted Prevention ◽  
Cancer Burden ◽  
Incidence And Mortality ◽  
Disease Study

Background: Liver cancer is one of the leading causes of cancer-related deaths worldwide. The primary causes of liver cancer include hepatitis B virus (HBV), hepatitis C virus (HCV), alcohol consumption, nonalcoholic fatty liver disease, and other factors. Aims: The objective of this study was to evaluate the global and sex-, age-, region-, country-, and etiology-related liver cancer burden, as well as the trends in liver cancer caused by different etiologies. Methods: The causes of liver cancer from 1990 to 2017, including global, regional, and national liver cancer incidence, mortality, and etiology, were collected from the Global Burden of Disease study 2017, and the time-dependent change in the trends of liver cancer burden was evaluated by annual percentage change. Results: The global liver cancer incidence and mortality have been increasing. There were 950,000 newly-diagnosed liver cancer cases and over 800,000 deaths in 2017, which is more than twice the numbers recorded in 1990. HBV and HCV are the major causes of liver cancer. HBV is the major risk factor of liver cancer in Asia, while HCV and alcohol abuse are the major risk factors in the high sociodemographic index and high human development index regions. The mean onset age and incidence of liver cancer with different etiologies have gradually increased in the past 30 years. Conclusions: The global incidence is still rising and the causes have national, regional, or population specificities. More targeted prevention strategies must be developed for the different etiologic types in order to reduce liver cancer burden.

Sex differences in stroke metrics among Southeast Asian countries: Results from the Global Burden of Disease Study 2015

2019 ◽  
Vol 14 (8) ◽  
pp. 826-834
Author(s):  
Wen Yea Hwong ◽  
Michiel L Bots ◽  
Sharmini Selvarajah ◽  
Sheamini Sivasampu ◽  
Daniel D Reidpath ◽  
...  
Keyword(s):  
Sex Differences ◽  
Ischemic Stroke ◽  
Southeast Asia ◽  
Burden Of Disease ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Stroke Mortality ◽  
Stroke Incidence ◽  
Incidence And Mortality ◽  
Disease Study

Background Sex differences in cardiovascular diseases generally disadvantage women, particularly within developing regions. Aims This study aims to examine sex-related differences in stroke metrics across Southeast Asia in 2015. Furthermore, relative changes between sexes are compared from 1990 to 2015. Methods Data were sourced from the Global Burden of Disease Study. Incidence and mortality from ischemic and hemorrhagic strokes were explored with the following statistics derived: (1) women-to-men incidence/mortality ratio and (2) relative percentage change in rate. Results Women had lower incidence and mortality from stroke compared to men. Notable findings include higher ischemic stroke incidence for women at 30–34 years in high-income countries (women-to-men ratio: 1.3, 95% CI: 0.1, 16.2 in Brunei and 1.3, 95% CI: 0.5, 3.2 in Singapore) and the largest difference between sexes for ischemic stroke mortality in Vietnam and Myanmar across most ages. Within the last 25 years, greater reductions for ischemic stroke metrics were observed among women compared to men. Nevertheless, women below 40 years in some countries showed an increase in ischemic stroke incidence between 0.5% and 11.4%, whereas in men, a decline from −4.2% to −44.2%. Indonesia reported the largest difference between sexes for ischemic stroke mortality; a reduction for women whereas an increase in men. For hemorrhagic stroke, findings were similar: higher incidence among young women in high-income countries and greater reductions for stroke metrics in women than men over the last 25 years. Conclusions Distinct sex-specific differences observed across Southeast Asia should be accounted in future stroke preventive guidelines.

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