scholarly journals Diagnostic Accuracy of FOBT and Colorectal Cancer Genetic Testing: A Systematic Review & Meta-Analysis

2019 ◽  
Vol 85 (1) ◽  
Author(s):  
Abdul Rahman Ramdzan ◽  
Muhammad Aklil Abd Rahim ◽  
Aznida Mohamad Zaki ◽  
Zuraidah Zaidun ◽  
Azmawati Mohammed Nawi
Keyword(s):  
Colorectal Cancer ◽  
Systematic Review ◽  
Genetic Testing ◽  
Diagnostic Accuracy ◽  
Meta Analysis ◽  
Cancer Genetic

scholarly journals Diagnostic accuracy of follow‐up tests for detecting colorectal cancer recurrences in primary care: A systematic review and meta‐analysis

2021 ◽  
Author(s):  
Geertje B. Liemburg ◽  
Daan Brandenbarg ◽  
Marjolein Y. Berger ◽  
Saskia F.A. Duijts ◽  
Gea A. Holtman ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Systematic Review ◽  
Primary Care ◽  
Diagnostic Accuracy ◽  
Meta Analysis

scholarly journals Diagnostic and Prognostic Significance of MiR-150 in Colorectal Cancer: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 10 (3) ◽  
pp. 99
Author(s):  
Daniel Sur ◽  
Claudia Burz ◽  
Shanthi Sabarimurugan ◽  
Alexandru Irimie
Keyword(s):  
Colorectal Cancer ◽  
Systematic Review ◽  
Diagnostic Accuracy ◽  
Prognostic Value ◽  
Meta Analysis ◽  
Treatment Options ◽  
Prognostic Significance ◽  
High Specificity ◽  
Diagnostic Biomarker ◽  
Specificity And Sensitivity

Although treatment options have improved, the survival and quality of life of colorectal cancer (CRC) patients remain dismal. Therefore, significant biomarker prediction may help to improve colorectal cancer patient’s prognosis profile. MiRNAs have come as an option because of their essential role in cancer initiation and progression by regulating several molecular processes. MiR-150 has different roles in cancer, but its function in CRC is still ambiguous. We undertook a systematic review and meta-analysis according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) research criteria by interrogating several databases in order to assess the diagnostic accuracy and prognostic value of miR-150. Additionally, clinicalgov.org was scanned for possible trials. The literature was screened from inception to February 2020. A total of 12 out of 70 full-text articles were included in the meta-analysis. Among these, nine studies were included for diagnostic accuracy, and the remaining three were considered for prognostic significance of miR-150. With our results, miR-150 is an appropriate diagnostic biomarker, especially in serum and plasma, while the prognostic value of miR-150 was not statistically significant. The present study findings suggest that miR-150 has high specificity and sensitivity values as a potential diagnostic biomarker in colorectal cancer patients.

scholarly journals A systematic review and meta-analysis of the diagnostic accuracy of pyruvate kinase M2 isoenzymatic assay in diagnosing colorectal cancer

2015 ◽  
Vol 13 (1) ◽  
pp. 48 ◽  
Author(s):  
Mallikarjuna Uppara ◽  
Franklin Adaba ◽  
Alan Askari ◽  
Susan Clark ◽  
George Hanna ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Systematic Review ◽  
Diagnostic Accuracy ◽  
Pyruvate Kinase ◽  
Meta Analysis ◽  
Pyruvate Kinase M2
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