scholarly journals Trends in Lung Cancer and Smoking Behavior in Italy: An Alarm Bell for Women

2017 ◽  
Vol 103 (6) ◽  
pp. 543-550 ◽  
Author(s):  
Annalisa Trama ◽  
Roberto Boffi ◽  
Paolo Contiero ◽  
Carlotta Buzzoni ◽  
Roberta Pacifici ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Survival ◽  
Smoking Behavior ◽  
Cancer Control ◽  
Lung Cancer Mortality ◽  
Tobacco Consumption ◽  
Mortality Trends ◽  
Incidence And Mortality ◽  
Key Driver ◽  
The 1960S

Introduction The epidemiology of lung cancer is changing worldwide, with smoking being the key driver of lung cancer incidence and mortality. Our aim is to analyze the incidence, survival and mortality trends in Italy in the framework of the 2017 survey on smoking behavior in Italy. Methods AIRTUM 2017 reports on cancer survival and incidence; 2017 survey on smoking behavior in Italy. Results Men achieved progress in lung cancer control characterized by a decrease in incidence and mortality and an increase in survival. The decreasing use of tobacco in men (from 60% in the 1960s to 24% in 2017) was most likely responsible for the decreasing incidence and mortality. Women showed no progress: although survival improved slightly, the incidence and mortality were both on the rise. This was most likely due to the increasing smoking rates in women in the 1970s and 80s. Of major concern is the accelerated rise in the number of smoking women from 4.6 million in 2016 to 5.7 million in 2017 compared to the decrease observed in men (from 6.9 to 6 million). Conclusions The incidence and mortality trends in males clearly demonstrate that primary prevention is the most effective way to reduce lung cancer mortality. By contrast, a 24% increase in the prevalence of smoking among women in just 1 year is extremely worrying for the future, and calls for immediate action by targeted strategies to reduce tobacco consumption in women and avert the dreadful prospect of a lung cancer epidemic in Italy.

scholarly journals Lung cancer survival trend in Umbria, Italy, 1994-2016: preliminary results

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
A Ostorero ◽  
A Gili ◽  
S Violi ◽  
F Stracci
Keyword(s):  
Lung Cancer ◽  
Overall Survival ◽  
Tobacco Smoking ◽  
Cancer Survival ◽  
Cancer Control ◽  
Mortality Trends ◽  
Incidence And Mortality ◽  
New Treatments ◽  
Lung Cancer Survival

Abstract Background Lung cancer is the second most common cancer worldwide and the leading cause of death for cancer (18.4%). During the last 30 years, lung cancer incidence and mortality increased in women and decreased in men, because of tobacco smoking exposure. Population survival trend reflects both the influence of disease severity at diagnosis and treatment effectiveness. Some studies reported an increase in global lung cancer survival and linked it to new treatment options. However, change in the overall survival may also reflect a shift towards morphologies with more favorable prognosis. We analyzed overall and morphology specific survival trends for lung cancer to gain insight on the role of new treatments and changing exposures. Methods We analyzed lung cancer 1 y-survival and 3 y-survival after diagnosis in Umbria (890'000 inhabitants) in the period 1994-2016. Population-based data were obtained from the Umbrian Cancer Registry (RTUP), Italy. We estimated relative net survival (Pohar-Perme approach) stratified both for sex and histotype (NSCLC, SCLC, NOS), considering six diagnostic periods from 1994 to 2016 (4 years for period, except 3 in the last one) for 5'268 lung cancer cases (26% women). Results Overall survival by gender resulted 40,5% (1y) and 16.5% (3y) in men, 47,3% (1y) and 23,2% (3y) in women. NSCLC survival increased in women during the period 1994-2016 from 41% to 53% (1y) and from 23% to 33% (3y), and remained unchanged in men. SCLC 3 year-survival did not change significantly neither in women nor in men. Conclusions We did not observe a significant increase in lung cancer survival over a 25 years period. We observed a significant increase in survival probabilities for NSCLC among women only. Thus, our data don't confirm a major role of new treatments in improving lung cancer control. We will provide further analyses for adenocarcinoma and a comparison of incidence and mortality trends to understand the influence of exposures and treatments on survival. Key messages A general increase in lung cancer survival, as could be expected after the introduction of new highly effective treatments is not present in western countries. Reducing exposure to tobacco smoking and environmental pollution remain the main intervention to improve lung cancer control.

scholarly journals Lung Cancer Mortality Trends in a Brazilian City with a Long History of Asbestos Consumption

2019 ◽  
Vol 16 (14) ◽  
pp. 2548 ◽  
Author(s):  
Gisele Aparecida Fernandes ◽  
Eduardo Algranti ◽  
Gleice Margarete de Souza Conceição ◽  
Victor Wünsch Filho ◽  
Tatiana Natasha Toporcov
Keyword(s):  
Lung Cancer ◽  
Cancer Mortality ◽  
Asbestos Exposure ◽  
Lung Cancer Mortality ◽  
Epidemiological Studies ◽  
Sao Paulo ◽  
São Paulo ◽  
Mortality Trends ◽  
Risk Of Death ◽  
Incidence And Mortality

There are scarce epidemiological studies on lung cancer mortality in areas exposed to asbestos in developing countries. We compared the rates and trends in mortality from lung cancer between 1980 and 2016 in a municipality that made extensive use of asbestos, Osasco, with rates from a referent municipality with lower asbestos exposure and with the rates for the State of São Paulo. We retrieved death records for cases of lung cancer (ICD-9 C162) (ICD-10 C33 C34) from 1980 to 2016 in adults aged 60 years and older. The join point regression and age-period-cohort models were fitted to the data. Among men, there was an increasing trend in lung cancer mortality in Osasco of 0.7% (CI: 0.1; 1.3) in contrast to a mean annual decrease for Sorocaba of -1.5% (CI: −2.4; −0.6) and a stable average trend for São Paulo of -0.1 (IC: −0.3; 0.1). Similar increasing trends were seen in women. The age-period-cohort model showed an increase in the risk of death from 1996 in Osasco and a reduction for Sorocaba and São Paulo State during the same period. Our results point to a need for a special monitoring regarding lung cancer incidence and mortality in areas with higher asbestos exposure.

scholarly journals Lung cancer incidence and mortality trends in the Republic of Belarus (1990-2019)

2021 ◽  
Vol 62 (4) ◽  
pp. 9-15
Author(s):  
V. Kurchin ◽  
A. Kurchenkov ◽  
A. Evmenenko ◽  
L. Levin
Keyword(s):  
Lung Cancer ◽  
Cancer Incidence ◽  
Cancer Mortality ◽  
Incidence Structure ◽  
Lung Cancer Mortality ◽  
Lung Cancer Incidence ◽  
Mortality Trends ◽  
Incidence And Mortality ◽  
Icd 10 ◽  
The Republic

favorable malignant diseases globally. In the Republic of Belarus, it ranks third (8.2%) in the cancer incidence structure and first (21.5%) in the cancer mortality structure. The object of the study were the lung cancer incidence and mortality trends in the Republic of Kazakhstan in 1990-2019. Methods: The present study included all patients - residents of Belarus, registered in the national cancer registry from 1990 to 2019 with a diagnosis of lung cancer (ICD-10 code: C33-C34). Demographic variables included gender, age, and area of residence (urban or rural). The number of PD cases is presented as absolute values and rough intensity indicators per 100,000 population. Standardized morbidity and mortality rates are calculated using the world standard (World) and are indicated per 100,000 population. Results: In the study period, the standardized incidence rate decreased from 27.5 to 25.6 per 100 000 population (– 7.1%, p<0.01). In males, it decreased from 62.1 to 54.6 per 100 000 males (– 12.1%, p<0.001); in females, it increased from 5.3 to 6.4 per 100 000 females (+20.7%, p<0.05). The standardized lung cancer mortality rate has decreased over the study period from 23.0 to 18.3 per 100 000 population (– 20.4%, p<0.001). In males, it went down from 53.6 to 40.7 (– 24.1%, p<0.001), and in women it changed slightly from 3.6 to 3.7 (+2.8%, p>0.05) per 100 000 of the relevant sex. The average annual increase in standardized mortality decreased eight times faster than the growth in standardized incidence. Conclusion: In the Republic of Belarus, lung cancer incidence is increasing in males and decreasing in females. At that, lung cancer mortality is decreasing. Quality specialized cancer care creates conditions for quicker negative growth of lung cancer standardized mortality vs. incidence

scholarly journals Descriptive-epidemiological characteristics of lung cancer in Serbia

2008 ◽  
Vol 61 (1-2) ◽  
pp. 16-21 ◽  
Author(s):  
Natasa Maksimovic ◽  
Kyriakos Spanopoulos
Keyword(s):  
Lung Cancer ◽  
Direct Method ◽  
Age Groups ◽  
Malignant Tumour ◽  
Mortality Rates ◽  
Malignant Tumours ◽  
Mortality Trends ◽  
Incidence And Mortality ◽  
The Republic ◽  
Epidemiological Characteristics

Introduction. Lung cancer represents the most common malignant tumour among men, and appears more and more frequently among women in many countries worldwide. The aims of this descriptive epidemiological study were to evaluate the mortality trends of all malignant tumours and lung cancer in Central Serbia from 1990 to 1999, and to estimate the incidence, mortality and the basic demographic characteristics of lung cancer in Central Serbia in 1999. Material and methods. The source of data concerning cancer cases in 1999 was the Cancer Registry of Central Serbia, while data of the Republic Statistics Institute were used for the analysis of mortality trends for the period 1990-1999. All rates were standardized by the direct method, to the world standard population. Confidence intervals for mortality rates were assessed with 95% level of probability. Linear regression coefficient was determined by Fisher's test. Results. The mortality rates showed rising tendencies for both lung cancer (y=-1876.26+0.96x, p=0.028 for men; y=654.78U).33x, p-0.001 for women) and all malignant tumours (y=-4139.88+2.15x, p=0.163 for men; y=3649.68 + 1.88x, p=0.016 for women), with statistically significant increase being observed for all trends, except all malignant tumours among men. In the year 1999, lung cancer ranked first among men and third among women, with 29.2% and 10.3% of cancer mortality respectively. The age-specific mortality rates were much higher in men in all age groups. Mortality increased with age and the highest rates were found in the age group 70-74 for both sexes. The highest incidence and mortality rates were reported in Belgrade, Moravicki and Sumadijski district. .

scholarly journals Lung cancer mortality due to delayed treatment: Literature review

2021 ◽  
Vol 60 (2) ◽  
pp. 36-38
Author(s):  
B. А. Abdurakhmanov ◽  
Z. К. Avizovа
Keyword(s):  
Lung Cancer ◽  
Cancer Mortality ◽  
Survival Rates ◽  
Lung Cancer Mortality ◽  
Qualitative Assessment ◽  
Scientific Publications ◽  
Delayed Treatment ◽  
Incidence And Mortality ◽  
The Impact ◽  
Delay In Treatment

Lung cancer is still leading in the structure of cancer incidence and mortality worldwide. Delay in appropriate treatment increases the probability of death from this disease. Purpose: to study foreign scientific publications of recent years on the mortality from lung cancer due to delayed treatment. Results: The analysis of global literature for 2010-2020 shows that any delay in lung cancer treatment after establishing the diagnosis reduces the survival rates. Recent studies provide a qualitative assessment of the effect of delay in treatment on cancer mortality for prioritization and modeling. The indications for surgery, systemic treatment, and radiation therapy in seven types of cancer, including lung cancer, evidence a significant association between delay in treatment and increased mortality. The researchers believe that early diagnostics increase the treatment efficacy. Conclusion: Analyzing the barriers to timely treatment for lung cancer can help clarify and assess the impact of delayed treatment on survival. Policies designed to minimize delays in treatment can improve survival outcomes.

Lung Cancer Mortality Trends in Spain Between 1980 and 2005

2008 ◽  
Vol 44 (2) ◽  
pp. 70-74 ◽  
Author(s):  
Aurelio Cayuela ◽  
Susana Rodríguez-Domínguez ◽  
José Luis López-Campos ◽  
Eduardo Vigil ◽  
Remedios Otero
Keyword(s):  
Lung Cancer ◽  
Cancer Mortality ◽  
Lung Cancer Mortality ◽  
Mortality Trends

Benefits of a centralized cancer control program on outcomes: Evaluation of wait times for diagnosis and management of advanced non-small cell lung cancer (NSCLC).

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. e19039-e19039
Author(s):  
Krista Noonan ◽  
Janessa J. Laskin ◽  
King Mong Tong ◽  
Katherine Ramsden ◽  
Yongliang Zhai ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Median Time ◽  
Palliative Therapy ◽  
Cancer Control ◽  
Geographic Location ◽  
Community Outreach ◽  
Control Program ◽  
Lung Cancer Mortality ◽  
Rank Test ◽  
Wait Times

e19039 Background: Canada has a national cancer registry that tracks patterns across the population; British Columbia (BC) has the lowest lung cancer mortality in the country. The BC Cancer Agency (BCCA) operates five regional cancer centres and community outreach sites that deliver cancer care using evidence-based standards and guidelines established by the BCCA. The province is 945,000 km2; the population is distributed 85% urban and 15% rural. We hypothesize that adherence to provincial cancer control programs results in equitable services in all geographic locations. Methods: A retrospective population-based review of stage IIIb/IV NSCLC patients (pts) diagnosed from Jan 2008 to Dec 2010 referred to the BCCA was done. Pt characteristics and time intervals between diagnosis, referral, oncology consultation and palliative therapy were extracted. The Kruskal-Wallis test was used to compare wait times (WT). The Kaplan-Meier method and log rank test was used for OS. Results: 1,431 pts were identified. Median time from diagnosis (DX) to referral (RF) was similar across all geographic regions (11-13 days). Median time from RF to oncology consultation ranged from 7-16 d. Table 1 describes medical oncology (MO) WT to chemotherapy (CT) and radiation oncology (RO) WT to radiotherapy (RT). Conclusions: While WT varied between key events in the pts’ lung cancer trajectory by geographic location, the overall survival from diagnosis was similar in all groups. Provision of provincially mandated guidelines and care conferred equitable outcomes in advanced NSCLC across BC. [Table: see text]

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