Hemodynamic Effects of Spiral ePTFE Prosthesis Compared with Standard Arteriovenous Graft in a Carotid to Jugular Vein Porcine Model

2010 ◽  
Vol 12 (3) ◽  
pp. 224-230 ◽  
Author(s):  
Ommid Kh. Jahrome ◽  
Imo Hoefer ◽  
Graeme J. Houston ◽  
Peter A. Stonebridge ◽  
Peter J. Blankestijn ◽  
...  
Keyword(s):  
Porcine Model ◽  
Jugular Vein ◽  
Arteriovenous Graft ◽  
Hemodynamic Effects

scholarly journals Efficacy of local dipyridamole therapy in a porcine model of arteriovenous graft stenosis

2006 ◽  
Vol 69 (12) ◽  
pp. 2179-2185 ◽  
Author(s):  
T. Kuji ◽  
T. Masaki ◽  
K. Goteti ◽  
L. Li ◽  
S. Zhuplatov ◽  
...  
Keyword(s):  
Porcine Model ◽  
Arteriovenous Graft ◽  
Graft Stenosis

scholarly journals A comparison of the hemodynamic effects of tracheal administration of vasopressin, adrenaline, and vasopressin plus adrenaline in a porcine model

2012 ◽  
Vol 2 (4) ◽  
pp. 103-106
Author(s):  
Pei-Chen Lin ◽  
Hung-Jung Lin ◽  
How-Ran Guo ◽  
Chih-Chan Lin ◽  
Kuo-Tai Chen
Keyword(s):  
Porcine Model ◽  
Hemodynamic Effects

Selective cerebral hypothermia induced via hypothermic retrograde jugular vein saline flush in a porcine model

2014 ◽  
Vol 36 (10) ◽  
pp. 897-902 ◽  
Author(s):  
Chih-Wei Chen ◽  
Varun Puvanesarajah ◽  
Sheng-Fu L. Lo ◽  
Tain-Junn Cheng ◽  
Chieh-Yang Cheng ◽  
...  
Keyword(s):  
Porcine Model ◽  
Jugular Vein

Locally Applied Recombinant Plasmin Results in Effective Thrombolysis in a Porcine Model of Arteriovenous Graft Thrombosis

2009 ◽  
Vol 20 (7) ◽  
pp. 951-958 ◽  
Author(s):  
Imo E. Hoefer ◽  
Erik S.G. Stroes ◽  
Gerard Pasterkamp ◽  
Marcel M. Levi ◽  
Jim A. Reekers ◽  
...  
Keyword(s):  
Porcine Model ◽  
Arteriovenous Graft ◽  
Graft Thrombosis

Differential Hemodynamic Effects of Levosimendan in a Porcine Model of Neonatal Hypoxia-Reoxygenation

Neonatology ◽  
2012 ◽  
Vol 101 (3) ◽  
pp. 192-200 ◽  
Author(s):  
J. Esch ◽  
C. Joynt ◽  
N. Manouchehri ◽  
T.F. Lee ◽  
Y.-Q. Li ◽  
...  
Keyword(s):  
Porcine Model ◽  
Hemodynamic Effects ◽  
Neonatal Hypoxia ◽  
Hypoxia Reoxygenation

scholarly journals Endovascular management of renal transplant dysfunction secondary to hemodynamic effects related to ipsilateral femoral arteriovenous graft

2016 ◽  
Vol 22 (2) ◽  
pp. 193-195
Author(s):  
Jason Salsamendi ◽  
Keith Pereira ◽  
David Quintana ◽  
Drew Bleicher ◽  
Marwan Tabbara ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Arteriovenous Graft ◽  
Endovascular Management ◽  
Hemodynamic Effects

Abstract 19325: Hemodynamic Effects of Guideline-compliant Asynchronous vs. Synchronous Ventilations During Cardiopulmonary Resuscitation in a Porcine Model

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Christiane Skåre ◽  
Theresa Olasveengen ◽  
Jo Kramer-Johansen ◽  
Fredrik Nordum ◽  
Eriksen Morten ◽  
...  
Keyword(s):  
Cardiopulmonary Resuscitation ◽  
Porcine Model ◽  
Blood Gas Analysis ◽  
Gas Analysis ◽  
Right Atrial ◽  
Hemodynamic Effects ◽  
Chest Compressions ◽  
Hemodynamic Variables ◽  
Airway Pressures ◽  
Normal Chest

Background: Current guidelines for cardiopulmonary resuscitation (CPR) emphasize reducing pauses in chest compressions, and suggest ventilating with 1 second inspiration time and with enough volume to produce normal chest rise 10 times per minute. No specific advice is provided on how ventilations should be timed with ongoing chest compressions. We have compared hemodynamic effects of ventilating synchronously vs. asynchronously during chest compressions in a porcine model. Methods: Twenty anaesthetized domestic pigs (approx. 30 kg) were randomized into two groups; synchronous vs. asynchronous ventilation. Ventricular fibrillation is induced electrically and left for 2 minutes before initiation of basic 30:2 CPR for 4 minutes. CPR with continuous mechanical chest compressions was continued for another 8 minutes with either synchronous or asynchronous ventilation before defibrillation was attempted. Aortic, right atrial and intracerebral pressures, carotid and cerebral blood flow and cardiac output (thermodilution) were measured. Airway monitoring included capnography and spirometry. Results: Hemodynamics, blood gas analysis and airway pressures were similar for both groups during baseline and 30:2 CPR periods. The asynchronous group had higher median peak inspiratory airway pressure (94 vs. 57 cm H 2 O, p<0.001) and lower EtCO 2 (1.8 vs. 3.5 kPa, p=0.023) compared to synchronous group during the last 30 seconds of CPR (after 12 minutes). Asynchronous group also had higher pH (7.55 vs. 7.35, p<0.001), lower pCO 2 (2.4 vs. 4.7, p<0.001) and higher pO 2 (62.1 vs. 29.4, p<0.001) compared to synchronous group. There were no significant differences in any of the measured hemodynamic variables between the two groups with similar coronary and cerebral perfusion pressures. ROSC was achieved in 5/10 vs. 3/10 animals in the synchronous and asynchronous groups, respectively. Conclusion: Synchronous and asynchronous ventilation during mechanical chest compressions provide similar hemodynamics, but guideline-compliant asynchronous ventilation yields significantly higher airway pressures and hyperventilation. Implications for lung injury need to be assessed.

Activated Protein C in the Cardioplegic Solution on a Porcine Model of Coronary Ischemia-Reperfusion has Deleterious Hemodynamic Effects

2006 ◽  
Vol 20 (2) ◽  
pp. 113-121 ◽  
Author(s):  
José A. Fernández ◽  
Antti E. Vento ◽  
Mikko Jormalainen ◽  
John H. Griffin ◽  
Ero Pesonen ◽  
...  
Keyword(s):  
Protein C ◽  
Porcine Model ◽  
Ischemia Reperfusion ◽  
Activated Protein C ◽  
Hemodynamic Effects ◽  
Cardioplegic Solution ◽  
Coronary Ischemia

Hemodynamic effects of PEEP in a porcine model of HCl-induced mild acute lung injury

2008 ◽  
Vol 53 (2) ◽  
pp. 190-202 ◽  
Author(s):  
C. K. MARUMO ◽  
D. A. OTSUKI ◽  
D. T. FANTONI ◽  
C. B. MARGARIDO ◽  
A. M. AMBRÓSIO ◽  
...  
Keyword(s):  
Acute Lung Injury ◽  
Lung Injury ◽  
Porcine Model ◽  
Hemodynamic Effects

A rat arteriovenous graft model using decellularized vein

Vascular ◽  
2020 ◽  
Vol 28 (5) ◽  
pp. 664-672
Author(s):  
Hualong Bai ◽  
Zhiwei Wang ◽  
Mingxing Li ◽  
Peng Sun ◽  
Wang Wang ◽  
...  
Keyword(s):  
Inferior Vena Cava ◽  
Inferior Vena ◽  
Jugular Vein ◽  
Animal Experiments ◽  
Vena Cava ◽  
Rat Aorta ◽  
High Rate ◽  
Large Animal ◽  
Arteriovenous Graft ◽  
Arteriovenous Grafts

Background The high rate of clinical failure of prosthetic arteriovenous grafts continues to suggest the need for novel tissue-engineered vascular grafts. We tested the hypothesis that the decellularized rat jugular vein could be successfully used as a conduit and that it would support reendothelialization as well as adaptation to the arterial environment. Materials and methods Autologous (control) or heterologous decellularized jugular vein (1 cm length, 1 mm diameter) was sewn between the inferior vena cava and aorta as an arteriovenous graft in Wistar rats. Rats were sacrificed on postoperative day 21 for examination. Results All rats survived, and grafts had 100% patency in both the control and decellularized groups. Both control and decellularized jugular vein grafts showed similar rates of reendothelialization, smooth muscle cell deposition, macrophage infiltration, and cell turnover. The outflow veins distal to the grafts showed similar adaptation to the arteriovenous flow. Both CD34, CD90 and nestin positive cells, as well as M1-type and M2-type macrophages accumulated around the graft. Conclusions This model shows that decellularized vein can be successfully used as an arteriovenous graft between the rat aorta and the inferior vena cava. Several types of cells, including progenitor cells and macrophages, are present in the host response to these grafts in this model. This model can be used to test the application of arteriovenous grafts before conducting large animal experiments.

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