Pre-operative Diagnosis of Scar Endometriosis by Aspiration Cytology

2011 ◽  
Vol 3 (4) ◽  
pp. 218-221
Author(s):  
Uma Handa ◽  
Irneet Mundi ◽  
Harsh Mohan

Purpose Endometriosis is a fairly common disease found in a variety of extra-uterine locations. Abdominal wall scar endometriosis usually presents as a cutaneous or subcutaneous mass which can be investigated easily by the noninvasive method of fine needle aspiration cytology (FNAC). Methods FNA was performed by a cytopathologist on three patients presenting with varying sized swellings near the cesarean section scar. Results The cytologic smears revealed a combination of epithelial cells, stromal cells, and variable number of hemosiderin-laden macrophages. A diagnosis of endometriosis was provided on FNAC and later confirmed on histopathology. Conclusions FNAC is a valuable, cost-effective. and safe tool for diagnosing scar endometriosis and thus permits correct management of the patient.

2000 ◽  
Vol 124 (11) ◽  
pp. 1667-1669
Author(s):  
Timothy Myers ◽  
Helen H. Wang

Abstract Objective.—To compare and contrast benign and malignant lesions of the breast that have similar appearances on fine-needle aspiration cytology and that constitute diagnostic pitfalls. Design.—The cytology files (dated November 1995 through May 1998) of the Beth Israel Deaconess Medical Center were searched to identify cases of breast fine-needle aspiration biopsies that were highly cellular and composed of bland-appearing spindle/columnar cells and that could represent either epithelial or stromal cells; these cases were reported as indeterminate (atypical/suspicious) and had subsequent excisional biopsies taken. Results.—Four such cases were found. Two were fibroadenomas and 2 were papillary carcinomas. Their appearances were strikingly similar on aspiration cytology. All cases were prepared with the ThinPrep method. On microscopic examination, all 4 cases were hypercellular and had many single cells and clusters of columnar/elongate cells. Immunocytochemistry proved these cells to be of epithelial origin. At least occasional bipolar stromal cells were seen in the background. The only appreciable difference between the benign and malignant cases was more significant nuclear atypia, which was barely discernible, in the malignant cases. Immunocytochemistry for smooth muscle actin was helpful in 2 cases that had sufficient material. Conclusions.—Some cases of fibroadenomas and papillary carcinomas can be very difficult, if not impossible, to distinguish on fine-needle aspiration cytology. Immunocytochemistry may be helpful if sufficient material is available. To avoid false-negative or false-positive diagnosis on cytology, it is best to report such cases as atypical or suspicious with final diagnosis pending excisional biopsy.


2012 ◽  
Vol 30 (3) ◽  
pp. 137-140 ◽  
Author(s):  
S M Shafiul Azam Chaudhury ◽  
Md Khurshid Alam ◽  
Md Serajul Haque

All breast lesions are not malignant, and all the benign lesions do not progress to cancer; however the accuracy of diagnosis can be increased by a combination of preoperative tests. About 30% of women suffer from breast disease in their lifetime. The main objectives are to explore the role of FNAC in diagnosis of breast disease at different ages. Fine needle aspiration cytology (FNAC) has become a critical component in the investigation of palpable breast masses. Total 208 cases included in this study at Comilla. The data was formulated and analyzed by SPSS-12. 79(37.98%) cases were at the age of 21-30 years and next one was 11-20 years which was 48(23.07%). Among them 40(19.23%) cases were   malignant and 168(80.77%) cases were benign in nature. The incidence of malignancy was increased with relation to age. As the age is more chance of malignancy is more. In benign types fibroadenoma was the common disease then the duct cell carcinoma, fibrocystic change, suppurative   inflammation respectively. The findings were 43.75%, 19.23%, 18.27% and 8.65%.In conclusion, fine needle aspiration cytology, for diagnosis of breast lump can reduce the number of open biopsy and   surgery. DOI: http://dx.doi.org/10.3329/jbcps.v30i3.12462 J Bangladesh Coll Phys Surg 2012; 30: 137-140


2018 ◽  
Vol 90 (5) ◽  
pp. 1-5 ◽  
Author(s):  
Ewa Machała ◽  
Jan Sopiński ◽  
Iulia Iavorska ◽  
Krzysztof Kołomecki

ABSTRACT Fine needle aspiration cytology (FNAC) is considered as the gold standard diagnostic test for the diagnosis of thyroid nodules. It is a cost-effective procedure that provides specific diagnosis rapidly with minimal complications. It plays an important role in the determination of treatment- patients with suspected malignancy diagnosis can be subjected to surgery. On the other hand it can decrease the rate of unnecessary surgeries. Aims: The aim of this study was to evaluate and compare the correlation, accuracy of fine needle aspirational cytology (FNAC) in the diagnosis of thyroid lesions with the final histopathologic diagnosis in the surgical specimens. Materials and Methods: In our study we have performed a retrospective analysis of a case series of patients who were admitted to the Department of Endocrine, General and Oncological Surgery of Hospital of M. Kopernik in Łodź (Poland) between May 2016 and December 2017 and underwent FNAC with subsequent surgery. Cytological diagnosis was classified into six Bethesda categories. Results: On cytological examination 1070/1262 were reported as benign, 49 malignant and 143 suspicious. On histopathological examination, 956/1070 cases were confirmed as benign but there were 114 discordant cases. Among the other cases histopathology diagnosis of malignancy matched in 45/49 and 128/143 cases.The sensitivity and specificity were 60,28% and 98,05% respectively. False positive rate was 1.95% and false negative rate was 39.72%. The positive predictive value was 90.1% and negative predictive value was 89.35%. Accuracy of FNA in differentiating benign from malignant thyroid lesions was 89,46%. Conclusions: Fine needle aspiration cytology is a simple, cost-effective and popular procedure for the diagnosis of thyroid cancer. It is recommended as the first line investigation for the diagnosis of thyroid lessions.


2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
A. B. Zarami ◽  
N. A. Satumari ◽  
M. Ahmed

Melanoma is one of the most aggressive malignant skin neoplasms worldwide with more than 20% of world melanoma seen in black Africa and Asia. Late presentation due to ignorance, poverty, and lack of adequate health facility in Nigeria is always the norms. We present this case report because of precision in diagnosis, using fine needle aspiration cytology (FNAC) to reemphasize that the technique is cheap, cost effective, and quick that can reduce the burden of incisional biopsy before definitive surgery and improve early detection of the disease especially in developing countries.


2018 ◽  
Vol 25 (10) ◽  
pp. 1492-1497
Author(s):  
Nazeer Ahmed Pathan ◽  
Abdul Aziz Shaikh ◽  
Abdul Aziz Shaikh ◽  
Manzoor Ali Shaikh

Objectives: Investigating cytopathological characteristics of thyroid swellingsby fine-needle aspiration cytology (FNAC) compared to histopathological examination. StudyDesign: Observational study. Place and Duration: Department of Pathology in collaborationwith Department of Surgery, Liaquat University of Medical and Health Sciences from November2014 to December 2016. Methods: A sample of 100 FNAC specimens was selected as perinclusion and exclusion criteria. FNAC procedure was conducted by technique of “to andfro movements” of needle for thyroid nodules of <1.5 cm size from central part of swelling.Peripheral part was aspirated in cases of large thyroid swellings. Smears were air dried andstained with May–Grunwald Giemsa (MGG) and H & E stain for histopathological examinationby microscopy. Data was analyzed on SPSS 22.0 at 95% confidence interval (p≤0.05). Results:Mean± SD age was noted as 47.6±8.6 years. Of total 200 cases, male and female were 90 (45%)& 110 (55%) respectively. Benign thyroid lesions were noted in 140 (70%), malignant thyroidlesions in 50 (25%) and 10 (5%) proved indeterminate thyroid lesions. FNAC shows sensitivityof 89%, specificity 97% and accuracy of 91%. Conclusion: FNAC is an easy, time escaping,cost- effective, simple procedure and valid technique for the triage of thyroid swellings.


Author(s):  
Dr. Amol R. Rajhans, MD ◽  
Dr. Deepak S. Howale

Lymph nodes are parts of the lymphatic system. Lymph node helps to filter out viruses, bacteria, cancer cells and other unwanted substances safely removed from the body. Lymphadenopathy is common clinical problem frequently give dilemma in diagnostic. Enlargement of lymph node is a common problem which evaluate as a Lymphadenopathy. An abnormality in size and character of lymph node in known as Lymphadenopathy which also consider as enlarged abnormally that measures more than 10mm in its diameter than normal. Lymphadenopathy is common clinical problem frequently give dilemma in diagnostic. Fine needle aspiration cytology (FNAC) has become an important tool for initial diagnosis and management for patients suffering from Lymphadenopathy because of early result, simple for test and minimal trauma to patient. The main aim of this study is to Correlation of Clinicopathological condition presenting with Lymphadenopathy. Role of FNAC in diagnosis will also evaluate with node biopsy and open lymph. Material and methods: Total 100 patients were included in this study. For all 100 patients fine needle aspiration cytology (FNAC) was done. In 75 cases excision biopsy was done. Pathological diagnosis was obtained in all cases. Fine needle aspiration cytology, excision biopsy, throat, ear and nose examination were carried out as a required base line investigations. Result: Total 80 patients were studies in this study. Out of this 80 patients 30 cases were IPD and remaining were OPD. FNAC as well as biopsy were carried out from total patients in this study. In this study Tubercular Lymphadenitis was observer maximum. Out of 80 patients 47(58.75%) were male and 33(41.25%) were female patients. Age group 20-30 years (35%) were maximum number of patients which was followed by 30-40 years (23.75%) and 10-20 years (21.25%) respectively was observed. Out of 80 patients 50(62.5%) were diagnosis as Tubercular Lymphadenitis and Chronic Non-specific Lymphadenitis was diagnosis in 10 (12.5%). Reactive lymphadenitis was diagnosed in 8(10%) patients whereas Malignant secondary’s were diagnosed in 7(8.75%) patients followed by 3(3.75%) patients suffer from lymphomas and 2(2.5%) were Non- Hodgkin's Lymphoma. Conclusion: Lymphadenopathy is a clinical evaluation followed by FNAC which is reliable diagnostic tool that is easy to perform; cost effective, speedy results accurate can be obtained. Specialist input is the main requirement for this. Biopsy is also useful in cases of lymphomas that act as diagnostic tool. When FNAC report is inconclusive, in nonspecific lymphadenitis than Biopsy is much helpful for accurate diagnosis and management. Hence, in cases of Lymphadenopathy FNAC was found to be reliable, simple and cost effective method for diagnosis.


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