scholarly journals Scalp Melanoma Diagnosed by Fine Needle Aspiration Cytology in a Tertiary Health Center

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
A. B. Zarami ◽  
N. A. Satumari ◽  
M. Ahmed

Melanoma is one of the most aggressive malignant skin neoplasms worldwide with more than 20% of world melanoma seen in black Africa and Asia. Late presentation due to ignorance, poverty, and lack of adequate health facility in Nigeria is always the norms. We present this case report because of precision in diagnosis, using fine needle aspiration cytology (FNAC) to reemphasize that the technique is cheap, cost effective, and quick that can reduce the burden of incisional biopsy before definitive surgery and improve early detection of the disease especially in developing countries.

2018 ◽  
Vol 90 (5) ◽  
pp. 1-5 ◽  
Author(s):  
Ewa Machała ◽  
Jan Sopiński ◽  
Iulia Iavorska ◽  
Krzysztof Kołomecki

ABSTRACT Fine needle aspiration cytology (FNAC) is considered as the gold standard diagnostic test for the diagnosis of thyroid nodules. It is a cost-effective procedure that provides specific diagnosis rapidly with minimal complications. It plays an important role in the determination of treatment- patients with suspected malignancy diagnosis can be subjected to surgery. On the other hand it can decrease the rate of unnecessary surgeries. Aims: The aim of this study was to evaluate and compare the correlation, accuracy of fine needle aspirational cytology (FNAC) in the diagnosis of thyroid lesions with the final histopathologic diagnosis in the surgical specimens. Materials and Methods: In our study we have performed a retrospective analysis of a case series of patients who were admitted to the Department of Endocrine, General and Oncological Surgery of Hospital of M. Kopernik in Łodź (Poland) between May 2016 and December 2017 and underwent FNAC with subsequent surgery. Cytological diagnosis was classified into six Bethesda categories. Results: On cytological examination 1070/1262 were reported as benign, 49 malignant and 143 suspicious. On histopathological examination, 956/1070 cases were confirmed as benign but there were 114 discordant cases. Among the other cases histopathology diagnosis of malignancy matched in 45/49 and 128/143 cases.The sensitivity and specificity were 60,28% and 98,05% respectively. False positive rate was 1.95% and false negative rate was 39.72%. The positive predictive value was 90.1% and negative predictive value was 89.35%. Accuracy of FNA in differentiating benign from malignant thyroid lesions was 89,46%. Conclusions: Fine needle aspiration cytology is a simple, cost-effective and popular procedure for the diagnosis of thyroid cancer. It is recommended as the first line investigation for the diagnosis of thyroid lessions.


Author(s):  
Dr. Amol R. Rajhans, MD ◽  
Dr. Deepak S. Howale

Lymph nodes are parts of the lymphatic system. Lymph node helps to filter out viruses, bacteria, cancer cells and other unwanted substances safely removed from the body. Lymphadenopathy is common clinical problem frequently give dilemma in diagnostic. Enlargement of lymph node is a common problem which evaluate as a Lymphadenopathy. An abnormality in size and character of lymph node in known as Lymphadenopathy which also consider as enlarged abnormally that measures more than 10mm in its diameter than normal. Lymphadenopathy is common clinical problem frequently give dilemma in diagnostic. Fine needle aspiration cytology (FNAC) has become an important tool for initial diagnosis and management for patients suffering from Lymphadenopathy because of early result, simple for test and minimal trauma to patient. The main aim of this study is to Correlation of Clinicopathological condition presenting with Lymphadenopathy. Role of FNAC in diagnosis will also evaluate with node biopsy and open lymph. Material and methods: Total 100 patients were included in this study. For all 100 patients fine needle aspiration cytology (FNAC) was done. In 75 cases excision biopsy was done. Pathological diagnosis was obtained in all cases. Fine needle aspiration cytology, excision biopsy, throat, ear and nose examination were carried out as a required base line investigations. Result: Total 80 patients were studies in this study. Out of this 80 patients 30 cases were IPD and remaining were OPD. FNAC as well as biopsy were carried out from total patients in this study. In this study Tubercular Lymphadenitis was observer maximum. Out of 80 patients 47(58.75%) were male and 33(41.25%) were female patients. Age group 20-30 years (35%) were maximum number of patients which was followed by 30-40 years (23.75%) and 10-20 years (21.25%) respectively was observed. Out of 80 patients 50(62.5%) were diagnosis as Tubercular Lymphadenitis and Chronic Non-specific Lymphadenitis was diagnosis in 10 (12.5%). Reactive lymphadenitis was diagnosed in 8(10%) patients whereas Malignant secondary’s were diagnosed in 7(8.75%) patients followed by 3(3.75%) patients suffer from lymphomas and 2(2.5%) were Non- Hodgkin's Lymphoma. Conclusion: Lymphadenopathy is a clinical evaluation followed by FNAC which is reliable diagnostic tool that is easy to perform; cost effective, speedy results accurate can be obtained. Specialist input is the main requirement for this. Biopsy is also useful in cases of lymphomas that act as diagnostic tool. When FNAC report is inconclusive, in nonspecific lymphadenitis than Biopsy is much helpful for accurate diagnosis and management. Hence, in cases of Lymphadenopathy FNAC was found to be reliable, simple and cost effective method for diagnosis.


Author(s):  
Nandinee Lahkar ◽  
Manoj Kumar Deka ◽  
Nitu Mani Khakhlari

Background: Annual incidence of thyroid nodules ranges from 40,000 to 70,000 per 1 lac population worldwide. Fine Needle Aspiration (FNA) of the thyroid is widely accepted simple, cost effective and quick to perform outpatient procedure with minimal complication. The National Cancer Institute (NCI) Bethesda, Maryland, United States standardized the reporting system for thyroid FNA by using Bethesda system for reporting thyroid cytopathology.Methods: FNA was performed in total 155 patients presenting with the thyroid swelling with or without Ultrasonography (USG) guidance. All patients were analyzed for age, gender, type of lesions. FNA was done and smears were examined and reported according to Bethesda system of reporting for thyroid cytopathology. Findings were correlated with post-operative histopathological diagnoses in 103 cases who underwent surgery.Results: Out of total 155 patients, 32 were male and 123 were female. Average age of presentation was 38.4 years. On cytology, according to Bethesda system, most cases were in benign category (76.1%) followed by malignant (8.4%). On histopathological study most common diagnosis was colloid goiter followed by papillary thyroid carcinoma. From the study it was found that sensitivity, specificity and accuracy of fine needle aspiration cytology of thyroid lesions were 81.8%, 97.3% and 95.4% respectively.Conclusions: Fine needle aspiration cytology is simple, easy to perform, cost effective procedure with high sensitivity, specificity and diagnostic accuracy in case of thyroid lesions.


Author(s):  
Nazia T. Sheikh ◽  
Sumat Ul Khurshid

Background: Fine Needle Aspiration Cytology (FNAC) is a procedure of choice as the first line of investigation in diagnosing non-neoplastic and neoplastic swellings of different areas as it has been found to be highly accurate and very useful, cost effective, offer early diagnosis after presentation and  treatment. In this present study in Department of pathology, data was collected and scrutinized. Cytology of various sites including breast, head and neck, salivary glands, thyroid, lymph nodes, etc. was done.Methods: FNAC is performed with the help of 21-22-gauge needle attached with 20 ml syringe by taking all aseptic precautions. Total of 70 cases were collected over a period of 4 months from April 2019 to July 2019.Results: Out of total 70 samples maximum number of cases were found in 21-30 years of age (16 cases); Males were 34(49%) and females were 36(51%) in number. 38 cases (54%) were non-neoplastic ,23 cases (33%) were neoplastic and in 9 cases (13%) no opinion was made. This study included 70 cytologically diagnosed cases. Out of which 38 cases (54%) were non-neoplastic, 23 cases (33%) neoplastic and in 9 cases (13%) no possible opinion could be made due to a number of factors like: Material not corresponding of representative area, small size of lesion, wrong technique, cystic areas, hemorrhage and necrosis and small foci of neoplastic lesion.Conclusions: Even though a number of limitations, FNAC has high accuracy in diagnosing benign and malignant lesions of various sites and thus reduces the period between presentation of tumours and their diagnosis which results in early management.


Author(s):  
Shivani Kumawat ◽  
V. M. Bhagat ◽  
Bhavna Gamit ◽  
B. M. Jha

Filariasis is a major public health problem in tropical countries, including India. Fine needle aspiration cytology plays an important role in prompt recognition of disease. Aim was to highlight the role of fine needle aspiration cytology as a simple and cost effective tool to detect microfilarial infestation. A retrospective study of 10 cases in which fine needle aspiration cytology was done and was useful in detecting microfilaria. Patient’s age were ranging from 19-62 years. M:F ratio being 7:3. Out of ten cases, maximum cases of microfilarial detection was reported in soft tissue swelling (four cases), followed by lymph node swelling (three cases), thyroid swelling (two cases) and breast swelling (one case). Careful screening of fine needle aspiration cytology smears is helpful in detecting microfilaria even in asymptomatic patients living in endemic zone which plays a significant role in recognition of disease and obviating severe manifestations of filariasis if treated in time.


2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
Manoj Gupta ◽  
Savita Gupta ◽  
Ved Bhushan Gupta

Background. Fine needle aspiration cytology is considered the gold standard diagnostic test for the diagnosis of thyroid nodules. Fine needle aspiration cytology is a cost effective procedure that provides specific diagnosis rapidly with minimal complications. Based on the cytology findings, patients can be followed in cases of benign diagnosis and subjected to surgery in cases of malignant diagnosis thereby decreasing the rate of unnecessary surgery. Purpose of the present study was to correlate the fine needle aspiration cytology findings with histopathology of excised specimens.Material and Methods. This was a prospective study conducted on 75 consecutive patients between January 2003 and December 2005. All patients with clinically diagnosed solitary thyroid nodule who were clinically and biochemically euthyroid were included for study. Patients with multinodular goitre and who were hypothyroid or hyperthyroid were excluded from the study.Results. The sensitivity, specificity, accuracy, false positive rate, false negative rate, positive predictive value, and negative predictive value of FNAC for the diagnosis of neoplastic solitary thyroid nodules were 80%, 86.6%, 13.3%, 20%, 80%, and 86.6%, respectively. Commonest malignancy detected was papillary carcinoma in 12 patients.Conclusions. Fine needle aspiration cytology is a simple, easy to perform, cost effective, and easily repeated procedure for the diagnosis of thyroid cancer. It is recommended as the first line investigation for the diagnosis of solitary thyroid nodule.


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