Contact Lens–Related Dry Eye and Ocular Surface Changes with Mapping Technique in Long-Term Soft Silicone Hydrogel Contact Lens Wearers

2012 ◽  
Vol 22 (7_suppl) ◽  
pp. 17-23 ◽  
Author(s):  
Tomris Sengor ◽  
Sevda Aydin Kurna ◽  
Nurver Ozbay ◽  
Semahat Ertek ◽  
Suat Aki ◽  
...  
2019 ◽  
Vol 42 (3) ◽  
pp. 273-277 ◽  
Author(s):  
Alberto López-de la Rosa ◽  
Cristina Arroyo-del Arroyo ◽  
Amalia Enríquez-de-Salamanca ◽  
José Pinto-Fraga ◽  
Alberto López-Miguel ◽  
...  
Keyword(s):  
Dry Eye ◽  

2012 ◽  
Vol 05 (01) ◽  
pp. 53
Author(s):  
Terrence P O’Brien ◽  

Seasonal and perennial allergic conjunctivitis are common conditions which, along with dry eye and other inflammatory disorders of the ocular surface, may present an underlying management challenge in refractive surgery. Optimizing the condition and health of the ocular surface is essential in contact lens wearers, refractive surgical candidates, and post-surgical patients alike. Achieving an optimal ocular surface demands a comprehensive understanding of ocular allergy and related ocular surface conditions, as well as a proactive therapeutic approach. Although ocular allergy has often been implicated in contact lens intolerance, research has now begun to document the potential impact of allergic conjunctivitis on refractive surgical outcomes as well. Additional studies are needed to understand the relationship of allergic conjunctivitis to concomitant ocular surface disease and long-term ocular surface health. Further investigation of the potential benefit of better management of chronic episodic ocular surface inflammation, particularly in refractive surgery, will assist with the identification of optimal therapies.


2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Frederick T. Fraunfelder ◽  
James J. Sciubba ◽  
William D. Mathers

The purpose of this paper is to review the possible role of polypharmacy in causing dry eye disease (DED), reflecting the complex interactions and complications associated with the use of multiple systemic and topical ocular medications. The pharmacological, physiological, anatomical, and histological mechanisms causing dry mouth differ little from those causing dry eye. Oral polypharmacy is the most common cause of dry mouth, but has not been investigated as a cause of dry eye. Topical ocular polypharmacy has been shown to cause DED. Information on drugs that likely cause or aggravate DED and the controversial role of preservatives in topical ocular medications are examined. Systemic or topical ocular medications and preservatives used in topical ocular drugs may cause dry eye through the drug's therapeutic action, ocular surface effects, or preservatives, and the effects probably are additive. Long-term use of topical ocular medications, especially those containing preservatives such as BAK, may play an important role in DED and the role of polypharmacy needs further study. We review possible ways to decrease the risk of medication-related dry eye.


2007 ◽  
Vol 23 (7) ◽  
pp. 385-390 ◽  
Author(s):  
Piera Versura ◽  
Michela Fresina ◽  
Emilio C. Campos

2021 ◽  
Vol 14 (4) ◽  
pp. 616-621
Author(s):  
Rou Sun ◽  
◽  
Xian-Qun Fan ◽  

Many patients with Graves' ophthalmopathy (GO) suffer from dry eye syndrome (DES), and this is one of the most common reasons of eye discomfort in patients with GO. The prevalence of DES in patients with GO is significantly higher than normal subjects. The ocular surface changes involving changes in tears, cornea, conjunctiva and glands occur in GO patients. However, the mechanism of how DES occurs in GO still remains unclear. In this review, the ocular surface changes were illustrated and analyzed the reasons for high prevalence of DES in GO patients.


2019 ◽  
Vol 32 (4) ◽  
pp. 260
Author(s):  
Fernando Trancoso Vaz ◽  
Susana Pinto Henriques ◽  
Diana Silveira Silva ◽  
Joana Roque ◽  
Ana Sofia Lopes ◽  
...  

Introduction: Given the increasing use of electronic devices, and the increasing number of complaints with its use, we intend to evaluate the prevalence of manifestations of dry eye and ocular fatigue in a population of individuals, who use the computer daily to perform all their professional tasks, as well as to correlate these complaints with the number of hours of digital use as well as their possible improvement with behavioural measures and use of tear drops.Material and Methods: A total of 77 individuals (154 eyes) were evaluated on two separate days with a 1-month interval. They completed two questionnaires: OSDI and PEG Eye Fatigue. An objective ocular surface assessment was performed: Schirmer test without anesthetic, DR-1a Dry Eye Monitor™, hyperemia evaluation, lacrimal break up, presence of keratitis and lesions in the conjunctiva, as well as near accommodation point and near convergence point. After the first evaluation, the subjects were divided into two groups: group A (< 2 hours of computer working) and group B (> 2 hours of computer working). Some environmental measures to reduce complaints and recommendation of use of artificial tears were explained to the latter.Results: There was a statistically significant difference in the majority of the parameters evaluated in the group B, in relation to the morning period (group A) - tear film (p = 0.032), hyperemia (p < 0.001), BUT (p < 0.001), keratitis (p < 0.001), conjunctival lesion (p = 0.002) and accommodation point (p < 0.001). In the evaluation – one month later - there were no statistically significant differences in any of the parameters analysed in the group A, and in group B there was a decrease in most parameters at the end of that period - Schirmer test (p = 0.005), lacrimal film (p = 0.022), keratitis (p < 0.001), conjunctival lesion (p = 0.005) and fatigue score (p < 0.001).Discussion: It was thus possible to show the appearance of ocular fatigue and ocular surface changes with prolonged use of computers (> 2 hours) as well as a significant improvement in symptomatology (subjective assessment) as well as of ocular surface changes (objective evaluation) with the implementation of postural measures, regular breaks and use of lubricants. This is the first study, to the best of our knowledge, of digital asthenopia in which, in addition to the subjective evaluation, the presence of ocular surface modifications (objective assessment) were evaluated and the respective improvement with the aforementioned ergophthalmological measures were evaluated.Conclusion: This survey highlights the increased overall level of awareness that we need to have to face the rapid and wide-scale changes driven by the emergence of digital technology and, more particularly, its impact on user’s vision and posture. We concluded that the longer we use the electronic devices (more than two hours) the more severe the complaints and rates of ocular surface changes are. Environmental and ocular strategies can attenuate or even eliminate the discomfort caused by this syndrome, and increase professional performance and quality of life.


RSC Advances ◽  
2019 ◽  
Vol 9 (29) ◽  
pp. 16578-16585 ◽  
Author(s):  
Jonghwan Mun ◽  
Jee won Mok ◽  
Sanghoon Jeong ◽  
Seonghwi Cho ◽  
Choun-Ki Joo ◽  
...  

A cholesterol-hyaluronate (C-HA) micelle embedded contact lens was developed for efficient hydrophobic drug loading and long-term controlled drug delivery.


2011 ◽  
Vol 52 (10) ◽  
pp. 7267 ◽  
Author(s):  
Kyung-Chul Yoon ◽  
Kyu-Youn Ahn ◽  
Won Choi ◽  
Zhengri Li ◽  
Ji-Suk Choi ◽  
...  

Cornea ◽  
2001 ◽  
Vol 20 (8) ◽  
pp. 820-825 ◽  
Author(s):  
Pierre-Jean Pisella ◽  
Florence Malet ◽  
Sophie Lejeune ◽  
Françoise Brignole ◽  
Caroline Debbasch ◽  
...  

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