Quality of Vision Index: A New Method to Appraise Visual Function Changes in Age-Related Macular Degeneration

2011 ◽  
Vol 21 (1) ◽  
pp. 55-66 ◽  
Author(s):  
Stefano Piermarocchi ◽  
Monica Varano ◽  
Mahachstina Parravano ◽  
Francesco Oddone ◽  
Mauro Sartore ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Visual Function ◽  
Age Related Macular Degeneration ◽  
New Method ◽  
Age Related ◽  
Quality Of Vision

scholarly journals Colour contrast sensitivity in eyes at high risk of neovascular age-related macular degeneration

2019 ◽  
Vol 30 (6) ◽  
pp. 1487-1494
Author(s):  
Antonio Calcagni ◽  
Olivia Howells ◽  
Frank Eperjesi ◽  
Hannah Bartlett ◽  
Alastair KO Denniston ◽  
...  
Keyword(s):  
High Risk ◽  
Macular Degeneration ◽  
Contrast Sensitivity ◽  
Age Related Macular Degeneration ◽  
Reference Database ◽  
Colour Contrast ◽  
Age Related ◽  
Quality Of Vision ◽  
Prospective Longitudinal

Purpose: To generate the first published reference database of colour contrast sensitivity in eyes at high risk of neovascular age-related macular degeneration and to explore this important feature in quality of vision. Background: Quality of vision depends on many factors. Changes in chromatic contrast sensitivity remain largely unexplored in eyes at high risk of neovascular age-related macular degeneration; they may however not only be relevant for quality of life but also an early indicator of the onset of the disease, so it is important to have a means to evaluate any variation in colour contrast sensitivity, especially in view of the likely increase in neovascular age-related macular degeneration as the population ages. Methods: This prospective longitudinal study evaluated colour contrast sensitivity along the protan and tritan colour axes in 145 eyes at high risk of neovascular age-related macular degeneration. Results: Colour contrast sensitivity showed statistically significant correlations with age and visual acuity, but not gender nor laterality (i.e. whether the right or left eye was being tested). There was significant variability among individuals, especially for the tritan axis, with some subjects well within normal limits for age and others with very poor colour contrast sensitivity. Conclusion: This study has generated the first published colour contrast sensitivity reference database for eyes at high risk of neovascular age-related macular degeneration. It has also shown a high inter-individual variability of colour contrast sensitivity in eyes at high risk of neovascular age-related macular degeneration, but the significance of this is unclear. Further work is required to establish if eyes with high colour contrast sensitivity thresholds (i.e. poor colour vision) have a higher risk of developing neovascular age-related macular degeneration over time, and this is the subject of ongoing work.

scholarly journals Scleral gas permeable contact lenses as a possible way of visual rehabilitation of patients with age-related macular degeneration

The Eye ◽  
2019 ◽  
Vol 125 (2019-1) ◽  
pp. 33-40
Author(s):  
Alexander Myagkov ◽  
Maria Kovalevskaya ◽  
Oksana Pererva
Keyword(s):  
Macular Degeneration ◽  
Contact Lenses ◽  
Gas Permeability ◽  
Age Related Macular Degeneration ◽  
Central Visual Field ◽  
Optimal Method ◽  
Visual Rehabilitation ◽  
Age Related ◽  
Quality Of Vision

Low visual acuity, loss of the central visual field, metamorphopsia, distortion of lines and decreased contrast sensitivity cause reduced quality of vision in patients with age-related macular degeneration (AMD). Currently existing methods of visual rehabilitation for patients with AMD, such as telescopic intraocular and scleral lenses, are functionally and cosmetically unacceptable. The use of intraocular telescopic lenses is limited by the high risk of postoperative complications, low functional parameters, as well as by difficult ophthalmoscopy and lasting adaptation of patients. Telescopic scleral lenses have а low resolution, contain impermeable to oxygen parts and require wearing special switching glasses. However, scleral lenses have potential in developing an optimal method for vision correction in patients with AMD due to the presence of following advantages: wide optical zone, gas permeability, correction of refractive astigmatism in presbyopic patients and alleviation of dry eye symptoms. In conclusion, further clinical researches are required to develop a method for improving the quality of vision in patients with AMD by using scleral lenses with an objective test for evaluating the effectiveness of correction – the 3D computer-automated threshold Amsler grid test (3D-CTAG).

scholarly journals Association of Vision-related Quality of Life with Visual Function in Age-Related Macular Degeneration

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Susanne G. Pondorfer ◽  
Jan. H. Terheyden ◽  
Manuel Heinemann ◽  
Maximilian W. M. Wintergerst ◽  
Frank G. Holz ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Visual Acuity ◽  
Macular Degeneration ◽  
Contrast Sensitivity ◽  
Visual Function ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
Related Quality ◽  
The Impact

Abstract The purpose of this study was to assess which visual function measures are most strongly associated with vision-related quality of life (VRQoL) in age-related macular degeneration (AMD). A cross-sectional study of subjects with early AMD (n = 10), intermediate AMD (n = 42) and late AMD (n = 38) was conducted. Subjects were interviewed with the Impact of Vision Impairment (IVI) questionnaire. Functional tests performed included best-corrected visual acuity (BCVA), low luminance visual acuity (LLVA), visual acuity measured with the Moorfields Acuity Charts (MAC), contrast sensitivity, reading speed, mesopic and dark-adapted microperimetry. The relationship between VRQoL and visual function was assessed with multiple regressions controlling for confounders. Rasch analysis demonstrated the validity of the IVI to assess VRQoL through three subscales: reading and accessing information, mobility and independence, and emotional well-being. Subjects with late AMD had significant lower IVI scores on all subscales compared with intermediate and early AMD (p < 0.011). In the overall cohort, IVI subscales were associated with BCVA, LLVA, MAC-VA and contrast sensitivity (all p < 0.001). Among the subgroup of early and intermediate AMD subjects, reading and mobility subscales were significantly associated with MAC-VA (p < 0.013). These results suggest that MAC-VA is a useful, patient-relevant measure of visual impairment in AMD.

scholarly journals Longitudinal Study of Visual Function in Dry Age-Related Macular Degeneration at 12 Months

2019 ◽  
Vol 3 (8) ◽  
pp. 637-648 ◽  
Author(s):  
S. Tammy Hsu ◽  
Atalie C. Thompson ◽  
Sandra S. Stinnett ◽  
Ulrich F.O. Luhmann ◽  
Lejla Vajzovic ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Macular Degeneration ◽  
Visual Function ◽  
Age Related Macular Degeneration ◽  
Age Related
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