scholarly journals Longitudinal Study of Visual Function in Dry Age-Related Macular Degeneration at 12 Months

2019 ◽  
Vol 3 (8) ◽  
pp. 637-648 ◽  
Author(s):  
S. Tammy Hsu ◽  
Atalie C. Thompson ◽  
Sandra S. Stinnett ◽  
Ulrich F.O. Luhmann ◽  
Lejla Vajzovic ◽  
...  
1997 ◽  
Vol 74 (3) ◽  
pp. 152-159 ◽  
Author(s):  
KAREN HOLOPIGIAN ◽  
WILLIAM SEIPLE ◽  
VIVIENNE GREENSTEIN ◽  
DANIEL KIM ◽  
RONALD E. CARR

2020 ◽  
Author(s):  
M Rizzi ◽  
K Powell ◽  
MR Robinson ◽  
T Matsuki ◽  
J Hoke ◽  
...  

AbstractMacular degeneration is the leading cause of blindness in the developed world. Whilst most patients lose sight owing to atrophic changes, no treatments currently exist that improve the vision deficit due to atrophy. Here, we identify loss of lateral inhibition as a specific mechanism by which photoreceptor degeneration reduces visual function beyond the atrophic area. We find that this inhibition is adaptive, and that if modulated can improve visual function, making inhibitory circuits an unexpected therapeutic target for age related macular degeneration and related disorders.


2016 ◽  
Vol 101 (2) ◽  
pp. 190-197 ◽  
Author(s):  
Kwadwo Owusu Akuffo ◽  
John M Nolan ◽  
Tunde Peto ◽  
Jim Stack ◽  
Irene Leung ◽  
...  

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