Tuberculosis and Diabetes Mellitus Co-Morbidity: Lessons to Learn From HIV/AIDS

2019 ◽  
Vol 1 (1) ◽  
pp. 12-21
Author(s):  
F.A. Ayeni ◽  
◽  
O.O. Oyetunde ◽  
B.A. Aina ◽  
◽  
...  

Tuberculosis (TB) and Diabetes mellitus (DM) are among the top ten causes of morbidity and mortality globally, with the Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) also causing significant mortality as well. The HIV-TB link has been well recognized since the beginning of the HIV epidemic, but link between TB and DM has only returned to the fore-front recentlyafter effective treatments for each condition reduced the association that was reported earlier in thetwentieth century. Recently also, urbanization, increasing age and sedentary lifestyle has led to an increase in diabetes prevalence. Diabetes mellitus is associated with a 3-fold incident risk of tuberculosis and, to a lesser extent, tuberculosis may also increase the risk of developing diabetes. Both diseasesinteract negatively at multiple levels, exacerbating and worsening the outcomes of the other. The impact of these co-morbidities particularly in developing countries of Sub Saharan Africa, of which Nigeria is one, is likely to be large. An increasing prevalence of diabetes mellitus may hinder efforts aimed at tuberculosis control, making successful TB treatment and control more difficult. Improved management of tuberculosis and diabetes could build on the successes of the TB-HIV/AIDS collaborative activities, and DOTS strategy, which emphasizes support to patients, as well as a reliable supply of quality-assured medicines. This review aims to examine the association between these two important diseases, and explore ways to manage and reduce mortality caused by the duo.

Entropy ◽  
2020 ◽  
Vol 22 (11) ◽  
pp. 1230 ◽  
Author(s):  
Shuman Sun ◽  
Zhiming Li ◽  
Huiguo Zhang ◽  
Haijun Jiang ◽  
Xijian Hu

Sub-Saharan Africa has been the epicenter of the outbreak since the spread of acquired immunodeficiency syndrome (AIDS) began to be prevalent. This article proposes several regression models to investigate the relationships between the HIV/AIDS epidemic and socioeconomic factors (the gross domestic product per capita, and population density) in ten countries of Sub-Saharan Africa, for 2011–2016. The maximum likelihood method was used to estimate the unknown parameters of these models along with the Newton–Raphson procedure and Fisher scoring algorithm. Comparing these regression models, there exist significant spatiotemporal non-stationarity and auto-correlations between the HIV/AIDS epidemic and two socioeconomic factors. Based on the empirical results, we suggest that the geographically and temporally weighted Poisson autoregressive (GTWPAR) model is more suitable than other models, and has the better fitting results.


2019 ◽  
Vol 9 (4) ◽  
pp. 415-431 ◽  
Author(s):  
Tawiah Kwatekwei Quartey-Papafio ◽  
Sifeng Liu ◽  
Sara Javed

Purpose The rise in malaria deaths discloses a decline of global malaria eradication that shows that control measures and fund distribution have missed its right of way. Therefore, the purpose of this paper is to study and evaluate the impact and control of malaria on the independent states of the Sub-Saharan African (SSA) region over the time period of 2010–2017 using Deng’s Grey incidence analysis, absolute degree GIA and second synthetic degree GIA model. Design/methodology/approach The purposive data sampling is a secondary data from World Developmental Indicators indicating the incidence of new malaria cases (per 1,000 population at risk) for 45 independent states in SSA. GIA models were applied on array sequences into a single relational grade for ranking to be obtained and analyzed to evaluate trend over a predicted period. Findings Grey relational analysis classifies West Africa as the highly infectious region of malaria incidence having Burkina Faso, Sierra Leone, Ghana, Benin, Liberia and Gambia suffering severely. Also, results indicate Southern Africa to be the least of all affected in the African belt that includes Eswatini, Namibia, Botswana, South Africa and Mozambique. But, predictions revealed that the infection rate is expected to fall in West Africa, whereas the least vulnerable countries will experience a rise in malaria incidence through to the next ten years. Therefore, this study draws the attention of all stakeholders and interest groups to adopt effective policies to fight malaria. Originality/value The study is a pioneer to unravel the most vulnerable countries in the SSA region as far as the incidence of new malaria cases is a concern through the use of second synthetic GIA model. The outcome of the study is substantial to direct research funds to control and eliminate malaria.


2018 ◽  
Vol 1 (1) ◽  
pp. 1-14
Author(s):  
Nicole Naadu Ofosu ◽  
L. Duncan Saunders ◽  
Gian Jhangri ◽  
Afif Alibhai

The impact of the widespread availability of antiretroviral therapy (ART) on the human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) related attitudes, behaviours and practices of the general population in Sub-Saharan Africa is understudied. We assessed the impact of ART availability on the fear of HIV/ AIDS (measured at both community and personal levels) and HIV prevention practices in Rwimi, Uganda using a cross-sectional survey. The fear of HIV/AIDS was described as a perceived threat to either self and/or community regarding the risk of contracting the disease, whereby the higher the perception of the threat, the greater the fear. We assessed associations between the outcomes of the dependent variables on both the community and personal fear of HIV/AIDS, and the independent variables of HIV/AIDS-related knowledge and demographics. Qualitative data was also generated from focus group discussions (FGD) on the context of the fear of HIV/AIDS and HIV pre- vention practices. The majority of participants (89.4%; males - 86.8%; females - 90.8%) felt that ART availability has reduced the fear of HIV/AIDS in the community. In contrast, fewer participants (22.4%; males - 24.4%; females – 21.2%) mentioned that their personal fear of HIV/AIDS has been reduced with the availability of ART. From the qualitative study, factors identified as influencing the fear of HIV/AIDS included stigma, fear of infection, and the inconvenience of being on ART. Although fear of HIV/AIDS persists, the fear is reduced because of the availability of life-prolonging ART. HIV prevention practices are influenced by socio-cultural norms (gender roles, relationship dynamics, power and trust), which, we argue, should be considered when de-signing sustainable HIV/AIDS prevention programs.


Africa ◽  
1994 ◽  
Vol 64 (2) ◽  
pp. 220-242 ◽  
Author(s):  
Beth Maina Ahlberg

In the current HIV debate there are diverse opinions about the spread of HIV/AIDS in Africa and the reasons for it. Caldwell and his colleagues, for example, argue that the whole of Africa has a distinct sexuality which is inherently permissive. They claim moreover that no religious moral value is attached to sexual activity, and Christianity has thus not succeeded in changing matters. They find in this failure the reason for the failure of the fertility control programme in sub-Saharan Africa, and they argue that HIV/AIDS control efforts will fail similarly unless the fear it generates forces Africans to adopt the Eurasian model, with its religious, moral value.The article re-examines Caldwellet al.'sconceptualisation of the role of moral value in social change. Without considering the internal expressions, mechanisms and social contexts within and through which moral value is maintained and changed, they assume that Christian moral values could lead to a change in sexual behaviour from permissive (as they see it) African sexuality to the Eurasian model. In making such an assumption they ignore the ethical and behavioural contradictions generally inherent in moral systems. Moreover they pay little attention to the process of change in Western societies, where Christian morality has lost a great deal of its control over behaviour. But even if we assume that internal contradictions and processes of change do not exist, the christianisation process in Africa fundamentally transformed local customs in ways that delinked their role in regulating behaviour, including sexual behaviour.For discussions and decisions on options and strategies for the prevention and control of HIV/AIDS, identifying the nature and impact of that transformation is essential.


2020 ◽  
Vol 20 (2) ◽  
pp. 568-578 ◽  
Author(s):  
Jamiu Adetola Odugbesan ◽  
Husam Rjoub

Background: The sub-Saharan Africa (SSA) present the highest prevalence of HIV/AIDS worldwide; resulting to a signif- icant development challenges at country, region and global level. The previous studies explain at least in part, the impact of the epidemic, however the impact of HIV/AIDS in long-term economic behavior were not yet clear. There is clearly few or absence of studies on the impact of the impact of the epidemic on sustainable development. Objective: This study focused on macroeconomic analysis of the HIV/AIDS impact on sustainable development in SSA. Method: The study utilized a panel dataset covering 23 countries from 1993 until 2016, and employed Panel ARDL/PMG. Results: Our findings reveals a stable long-run relationship between sustainable development and HIV/AIDS prevalence. The error correction coefficient was statistically significant and conclude that HIV/AIDS prevalence has long-run impact on sustainable development. Conclusion: The main implication of our study is that, achieving a sustainable development in the presence of high preva- lence of HIV/AIDS in SSA is very challenging and as such, the responsiveness of HIV/AIDS to sustainable development should be maintained at minimum which would require more efforts on HIV/AIDS control programs and increase health expenditure. Keywords: HIV/AIDS; macroeconomics; sustainable development; health expenditure; SSA.


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