Self-Assessment MCQ Questions Vol.1 No.2

2002 ◽  
Vol 1 (2) ◽  
Author(s):  
Martin Taylor ◽  
◽  
B Edmunds ◽  
Alison Evans ◽  
P J Francis ◽  
...  

(A Evans & M Taylor) · Diabetic Ketoacidosis 1. Only occurs in patients with a history of Insulin-treated Diabetes 2. Can be precipitated by Acute Pancreatitis 3. The diagnosis is excluded by a blood glucose less than 14 mmol/l 4. Has a higher mortality than Hyper-Osmolar Non-Ketotic coma 5. Patients with newly diagnosed Diabetes Mellitus rarely present with Diabetic Ketoacidosis · The Sliding Scale Insulin Regimen 6. 50 units of isophane insulin should be mixed in 50 mls of N/Saline and commenced at 6 units/hour 7. If there is a delay in commencing the intravenous sliding scale 10 units of soluble insulin should be given sub-cutaneously 8. Blood glucose falls of greater than 5 mmol/hour should be avoided 9. When the blood glucose falls to less than 5 mmol/l then the insulin infusion should be stopped 10. If the blood glucose remains above 20mmol/l additional bolus injections of insulin should be administered · Cerebral oedema in DKA 11. Is more common in children than adults 12. Typically occurs 4-12 hours after the start of treatment 13. If suspected clinically a CT scan should be performed prior to treatment with mannitol 14. Should be treated with mannitol 0.5g/kg 15. Intubation and hyperventilation may be required (AP Williams, T Krishna & AJ Frew) · The following statements are true of Anaphylaxis 16. Anaphylaxis results from generation of specific IgG antibody directed against an allergen 17. Biphasic reactions affect fewer than 5% of patients 18. Intravenous adrenaline is the treatment of choice 19. Bronchodilators such as salbutamol may be useful 20. Intravenous hydrocortisone will provide rapid relief from symptoms (G R Jones) · Regarding the antibiotic treatment of cellulitis 21. Aspiration of the lesion yields a pathogen in over 80% of cases 22. Cellulitis resulting from a bite injury may be due to an unusual pathogen 23. Oral agents may be as effective as vancomycin in treating MRSA cellulitis 24. 80% of patients are suitable for outpatient intravenous antibiotic therapy 25. Combination of gentamicin with penicillin enhances streptococcal killing (S Fletcher) · Indicators of life threatening asthma requiring immediate ICU admission are 26. PEFR < 200 l/min 27. Cyanosis despite high inspired FiO2 28. Generalized audible inspiratory and expiratory wheeze 29. Hypertension and tachycardia 30. Altered level of consciousness or confusion · CPAP and Non Invasive Ventilation 31. Has no place in the management of the asthmatic patient 32. May reduce the inspiratory work of breathing 33. May reduce air trapping 34. CPAP > 10 cm/H2O is most beneficial 35. Can be usefully combined with a heliumoxygen mix · Mechanical ventilation of asthmatic patients is 36. A straightforward therapeutic manoeuvre 37. Intubation is associated with severe acute complications 38. Requires a careful balancing act between high inspiratory flow and prolonged expiratory time 39. May not aim for normocapnoea 40. Is well tolerated (C Borland) · Pulmonary embolism 41. Is associated with a mortality of less than 5% 42. Is the most frequent cause of maternal death 43. Nowadays is rarely an unsuspected post mortem finding 44. Is found in a minority of patients undergoing perfusion lung scanning 45. Is usually due to genetic factors · For pulmonary embolism in women 46. The pill is a major risk factor 47. Warfarin may be safely given in pregnancy provided control is optimum 48. Warfarin may be safely given during breast feeding 49. Thrombolysis is indicated for massive post partum pulmonary embolism 50. Spiral CT is the imaging method of choice in pregnancy · In treatment of pulmonary embolism 51. Low molecular weight heparin is no more effective than unfractionated heparin 52. Warfarin can be started at diagnosis 53. Thrombolysis has not been shown to reduce mortality in hypotensive patients 54. Alteplase is preferred to streptokinase or urokinase 55. Inferior vena caval filters double the risk of deep vein thrombosis (P J Francis & B Edmunds) · Regarding direct ophthalmoscopy 56. The macula is located temporal to the optic disc 57. Blurring of the temporal margin of the optic disc can be a normal finding 58. To examine the red reflex, the patient is instructed to fixate over the examiner’s shoulder 59. Myopic examiners should set the dial on the ophthalmoscope on a minus lens (unless wearing their glasses) 60. Viewing the fundus of a myopic patient is challenging because the image is magnified · Regarding papilloedema 61. Visual loss occurs early in the disease 62. Unilateral swelling of the ONH excludes the diagnosis 63. Spontaneous venous pulsation will be absent 64. The presence of spontaneous venous pulsation excludes the diagnosis 65. The optic nerve head (ONH) swells because axoplasmic flow is interrupted

2019 ◽  
Vol 2019 ◽  
pp. 1-5 ◽  
Author(s):  
Johnny F. Jaber ◽  
Matthew Standley ◽  
Raju Reddy

Diabetic ketoacidosis (DKA) in pregnancy is associated with high fetal mortality rates. A small percentage of DKA occurs in the absence of high glucose levels seen in traditional DKA. Prompt recognition and management is crucial. We report a case of a 30-year-old pregnant woman with type 1 diabetes mellitus admitted with euglycemic DKA (blood glucose <200 mg/dL). Initial laboratory testing revealed a severe anion gap acidosis with pH 7.11, anion gap 23, elevated β-hydroxybutyric acid of 9.60 mmol/L, and a blood glucose of 183 mg/dL—surprisingly low given her severe acidosis. The ketoacidosis persisted despite high doses of glucose and insulin infusions. Due to nonresolving acidosis, her hospital course was complicated by spontaneous intrauterine fetal demise. Euglycemia and severe acidosis continued to persist until delivery of fetus and placenta occurred. It was observed that the insulin sensitivity dramatically increased after delivery of fetus and placenta leading to rapid correction of ketoacidosis. This case highlights that severe ketonemia can occur despite the absence of severely elevated glucose levels. We discuss the mechanism that leads to this pathophysiologic state and summarize previously published case reports about euglycemic DKA in pregnancy.


2002 ◽  
Vol 1 (3) ◽  
pp. 112-112

2002 Volume 1: 2 Cellulitis Diabetic Ketoacidosis Ventilation of the Asthmatic Pulmonary Embolism Anaphylaxis Volume 1: 3 Medical Emergencies in Pregnancy Non-Variceal GI Bleeding Atrial Fibrillation Neuroleptic Malignant syndrome / serotonin syndrome Myaesthenia Gravis


2003 ◽  
Vol 2 (1) ◽  
pp. 33-33

2002 Volume 1:2 Cellulitis Diabetic Ketoacidosis Ventilation of the Asthmatic Pulmonary Embolism Anaphylaxis Volume 1:3 Medical Emergencies in Pregnancy Non-Variceal GI Bleeding Atrial Fibrillation Neuroleptic Malignant syndrome / serotonin syndrome Myaesthenia Gravis


2002 ◽  
Vol 1 (2) ◽  
pp. 71-71

2002 Volume 1: 2 Cellulitis Diabetic Ketoacidosis Ventilation of the Asthmatic Pulmonary Embolism Anaphylaxis Volume 1: 3 Medical Emergencies in Pregnancy Non-Variceal Gastrointestinal Bleeding Atrial Fibrillation Chronic Obstructive Airway Disease Myaesthenia Gravis


2019 ◽  
Vol 4 (1) ◽  
pp. 26-28
Author(s):  
Júlio Garcia de Alencar ◽  
Geovane Wieblling da Silva ◽  
Sabrina Correa da Costa Ribeiro ◽  
Júlio Marchini ◽  
Rodrigo Neto ◽  
...  

The clinical presentation of diabetic ketoacidosis in pregnancy (DKP) is similar to that observed in nonpregnant women, although reports suggest the presenting blood glucose level may not be as high. It is hypothesized that lower, maternal fasting glucose levels are a result of both the fetus and the placenta consuming glucose. We report the case of a 38-year-old woman gravida 2, para 0, abortion 1 with type 1 diabetes who had euglycemic diabetic ketoacidosis and review the literature on DKP, with a focus on diagnosis, treatment, and monitoring of the mother and fetus.


2018 ◽  
Vol 16 (12) ◽  
pp. 909-919
Author(s):  
Lindy HERR ◽  
Ladda THIAMWONG

Diabetes is an increasingly common chronic disease that affects the body’s normal ability to control blood glucose levels due to impaired use of the hormone insulin. It is estimated that one out of every 4 adults who are hospitalized also have a diagnosis of diabetes. Diabetic inpatients face unique challenges in regards to managing their blood glucose while hospitalized due to the physiological stress of acute illness. Unfortunately, those who experience inadequate blood glucose management in the hospital are at an increased risk for poor patient outcomes, such as infection, increased length of stay, and death. There are multiple medications used to regulate blood sugar levels; however, the most commonly prescribed treatment for inpatients is the traditional sliding-scale regimen followed by the basal-bolus insulin regimen. An integrated literature review was conducted to determine if basal-bolus insulin is more effective than sliding-scale insulin in managing blood glucose levels of non-critically ill diabetic inpatients. Four well-known databases were searched and 5 relevant quantitative research articles were obtained and analyzed. The majority of the evidence supports basal-bolus insulin as the most effective treatment for managing blood glucose and preventing hyperglycemia without increasing the risk for hypoglycemia. Health care providers should order basal-bolus insulin accordingly in order to improve patient outcomes. Future research that questions why sliding-scale insulin is still widely prescribed may identify barriers related to ordering basal-bolus insulin and assist in decreasing related adverse events.


Author(s):  
Dario Pitocco ◽  
Mauro Di Leo ◽  
Linda Tartaglione ◽  
Emanuele Gaetano Rizzo ◽  
Salvatore Caputo ◽  
...  

Background: Diabetic Ketoacidosis (DKA) is one of the most commonly encountered diabetic complication emergencies. It typically affects people with type 1 diabetes at the onset of the disease. It can also affect people with type 2 diabetes, although this is uncommon. Methods: Research and online content related to diabetes online activity is reviewed. DKA is caused by a relative or absolute deficiency of insulin and elevated levels of counter regulatory hormones. Results: Goals of therapy are to correct dehydration, acidosis and to reverse ketosis, gradually restoring blood glucose concentration to near normal. Conclusion: Furthermore it is essential to monitor potential complications of DKA and if necessary, to treat them and any precipitating events.


2021 ◽  
Vol 69 (1) ◽  
Author(s):  
Nora El Said Badawi ◽  
Mona Hafez ◽  
Heba Sharaf Eldin ◽  
Hend Mehawed Abdelatif ◽  
Shimaa Atef ◽  
...  

Abstract Background The debate for the optimum sodium concentration in the rehydration solution in diabetic ketoacidosis (DKA) persists till the moment. The aim was to compare the outcome of 0.9% saline versus 0.45% saline in children with moderate and severe (DKA) regarding the effect on serum electrolytes, duration of DKA resolution and the incidence of hyperchloremia. Results A retrospective analysis of 121 children with moderate or severe DKA was done. After the initial 4 h in which both groups received normal saline, patients were divided into two groups continuing on 0.9% (N=72) or switched to 0.45% saline (N=49). Serum chloride and Cl/Na ratios were significantly higher in 0.9% saline group at 4 and 8 h. The 0.9% saline group had significantly higher proportion of hyperchloremia at 4 and 8 h (P value: 0.002, 0.02). The median duration of correction of DKA (14 h among 0.9% saline versus 10 h among 0.45% saline) without significant difference (P value= 0.43). The change in plasma glucose, effective osmolarity, corrected Na levels were comparable between groups. Conclusion There is an unavoidable iatrogenically induced rise in serum chloride with higher incidence of hyperchloremia with the use of normal saline in rehydration of children presenting in DKA and shock. The use of 0.45% saline as post-bolus rehydration fluid is not associated with a decline in the corrected serum sodium concentration and does not affect the rate of correction of acidosis or rate of drop in blood glucose or duration of DKA resolution when compared to normal saline.


Sign in / Sign up

Export Citation Format

Share Document