scholarly journals Evaluating the Genotoxic and Proximate Analysis of Ethanolic Extract of Lecaniodiscus cupanioides

2020 ◽  
Vol 2 (2) ◽  
pp. 14-20
Author(s):  
Oloyede A.M ◽  
Ottu B ◽  
Ogunsanwo K ◽  
Bolarinwa K ◽  
Makinde K ◽  
...  
Author(s):  
I. R. Jack ◽  
N. Nwachoko ◽  
U. H. Nwafor ◽  
G. I. Ndukwe

Garcinia kola (bitter kola) plays an important role in Africa ethnomedicine and traditional hospitality. Proximate and phytochemical composition of G. kola seeds as well as the effects of ethanolic and n-hexane extracts on the serum electrolytes of albino rats were studied using standard methods. Thirty-six albino rats of both sexes were used for the experiment. The animals were divided into nine groups of four rats per group. The groups were designated 1-9. Group 1 served as the control which was treated with normal saline. Groups 2-5 served as the groups treated with ethanolic extract of G. kola seeds and received 50, 125, 250 and 500 mg/kg body weight, while groups 6-9 served as the groups treated with n-hexane extract. After three weeks of treatment, the animals were sacrificed, and blood samples analyzed. Result of the proximate analysis showed that carbohydrate content was the highest (78.06%) while ash was the lowest (0.70%). Phytochemical result of G. kola seeds showed that tannins (0.342%) was the highest in terms of percent composition, followed by flavonoids (0.00764%); while alkaloids (0.00075%) was the lowest. Also, biochemical analysis revealed that the n-hexane extract of G. kola seeds was found to have slightly increased the activities of the serum electrolytes than the ethanolic extract. Conclusively, the results of this study showed that both extracts had effect on serum electrolytes of the albino rats, but the n-hexane extract had more toxic effect.


Author(s):  
Comfort Sankem Yusuf ◽  
Ibrahim Birma Bwatanglang ◽  
Tari Dlama Tizhe ◽  
Peter Emmanuel Tosin ◽  
Musa Ira Felister

This study was focused on the ethanobotanical survey, phytochemical and proximate analysis of Jatropha tanjorensis in Mubi. The ethnobotanical survey was carried out in some selected parts of both Mubi North and South local government area through oral interview using traditional medicine practioners and some householders as the interviewee. After air drying, pulverizing and extracting the bioactive constituents of the leaf using ethanol and water as solvents, the phytochemical and proximate analysis were carried out using a standard procedures. The ethnobotanical survey showed that, J. tanjorensis were used in the study area as a remedy to diseases such as: measles, scabies, malaria, high blood pressure, stomach ache, diabetes mellitus, eczema and anaemia with 74 % of the interviewee mentioning leaves as part mostly used. The qualitative phytochemical screening indicated the presence of compounds, namely: tannins, alkaloids, phenols, flavonoids, saponins, terpenoids, glycosides and anthraquinones in both the ethanoic and aqueous leaf extracts except terpenoids which was not detected in the ethanolic extract. The quantitative analysis showed glycosides (4.12 mg/100 g) and flavonoids (3.45 mg/100 g) as the highest compound in the ethanolic and aqueous extracts respectively. Carbohydrate was shown to be the highest proximate constituent with 52.38 % and fat the least with 1.76 %. Therefore, J. tanjorensis is rich in bioactive constituents and the leaves are mostly the plant part used as a remedy to illnesses such measles, scabies, malaria, high blood pressure, stomach ache, diabetes mellitus, eczema and anaemia.


2009 ◽  
pp. 1-11 ◽  
Author(s):  
Nick Kalogeropoulos ◽  
Spyros Konteles ◽  
Ioannis Mourtzinos ◽  
Elena Troullidou ◽  
Antonia Chiou ◽  
...  
Keyword(s):  

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
PMW Zago ◽  
IMO Sousa ◽  
MP Jorge ◽  
L Servat ◽  
N de C Queiroz ◽  
...  

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
T Ratanavalachai ◽  
S Thitiorul ◽  
S Tanuchit ◽  
A Itharat ◽  
I Sakpakdeejaroen

Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
T Ratanavalachai ◽  
S Thitiorul ◽  
A Itharat ◽  
N Runraksa ◽  
S Ruangnoo

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