Factors Influencing the T-50 Value

1941 ◽  
Vol 14 (2) ◽  
pp. 501-513
Author(s):  
E. R. Gardner
Keyword(s):  
Accurate Method ◽  
Independent Method ◽  
The State ◽  
Routine Test ◽  
Metallic Oxides ◽  
Sulfur Determination ◽  
State Of Affairs ◽  
Sulfur Containing ◽  
Rubber Article

Abstract The paramount importance of producing the correct state of cure in a rubber article is too well known to need further emphasis. In the light of this, statement, the necessity of possessing a convenient and accurate method of assessing the state of cure is obvious. Before the advent of the T-50 test, the state of cure was measured mainly by a determination of the quantity of sulfur combined with the rubber, of stress-strain properties, or of optimum resistance to aging. The determination of combined sulfur has a disadvantage which is immediately apparent; it is laborious. Also, the figure obtained includes the amount of sulfur combined with metallic oxides used as activators, and to get an accurate measure of the quantity of sulfur combined with the rubber, a second analysis must be undertaken. There is yet another disadvantage, namely, that sulfur-containing substances added to the rubber mix interfere with the determination. The determination of tensile strength, modulus, or resistance to aging cannot be regarded as suitable for giving an accurate measure of cure, and are probably best looked on as complementary to the sulfur determination. With this state of affairs existing, it was only to be expected that, on the introduction of an entirely new and independent method of testing the state of cure, far-reaching claims should have been made, and also that the discovery should have been hailed as the elixir for all cure-testing ills. The present work was undertaken with a view to testing the validity of the claims put forward and to investigating, prior to the introduction of the T-50 as a routine test, the effect of variables likely to be encountered.

scholarly journals What are Emotions? Structure and Function of Emotions

Studia Humana ◽  
2016 ◽  
Vol 5 (3) ◽  
pp. 29-44
Author(s):  
Cezary Mordka
Keyword(s):  
The State ◽  
Physiological Changes ◽  
Reliable Determination ◽  
Stipulative Definition ◽  
The Subject ◽  
Set Up ◽  
State Of Affairs ◽  
Definition Of ◽  
And Function

Abstract This paper attempts to coin a stipulative definition of “emotions” to determine their functions. In this sense, “emotion” is a complex phenomenon consisting of an accurate (reliable) determination of the state of affairs in relation to the state of the subject and specific “points of adaptation”. Apart from the cognitive aspect, this phenomenon also includes behavior, physiological changes and expressions (facial expression, voice, posture), feelings, and “execution” of emotions in the nervous system. Emotions fulfill informative, calibrating, identifying, existential, and motivating functions. Emotions capture the world as either positive or negative, important or unimportant, and are used to determine and assign weightings (to set up a kind of hierarchy). They emerge automatically (involuntarily), are difficult (or hardly possible) to control and are (to some extent) influenced by culture.

A Better Solution to the General Problem of Creation

2017 ◽  
Vol 9 (1) ◽  
pp. 147-162
Author(s):  
Jeremy W. Skrzypek
Keyword(s):  
Recent Work ◽  
General Problem ◽  
The State ◽  
State Of Affairs ◽  
Better Than

It is often suggested that, since the state of affairs in which God creates a good universe is better than the state of affairs in which He creates nothing, a perfectly good God would have to create that good universe. Making use of recent work by Christine Korgaard on the relational nature of the good, I argue that the state of affairs in which God creates is actually not better, due to the fact that it is not better for anyone or anything in particular. Hence, even a perfectly good God would not be compelled to create a good universe.

A model of the analysis of the dynamics and structure of socio-economic development (an example of the set of the largest Polish cities in the years 1998–2015)

2019 ◽  
Vol 63 (1) ◽  
pp. 25-37
Author(s):  
Lidia Mierzejewska ◽  
Jerzy Parysek
Keyword(s):  
Principal Component Analysis ◽  
Economic Development ◽  
Development Process ◽  
Principal Component ◽  
The State ◽  
Geographical Research ◽  
Development Policies ◽  
Socio Economic Development ◽  
Development Processes ◽  
State Of Affairs

Abstract The complexity of the reality studied by geographical research requires applying such methods which allow describing the state of affairs and ongoing changes in the best possible way. This study aims to present a model of research on selected aspects of the dynamics and structure of socio-economic development. The idea was to determine whether we deal with the process of reducing or widening the differences in terms of individual features. The article primarily pursues a methodological goal, and to a lesser extent an empirical one. The methodological objective of the paper was to propose and verify a multi-aspect approach to the study of development processes. The analyses carried out reveal that in terms of the features taken into account in the set of 24 of the largest Polish cities the dominating processes are those increasing differences between cities, which are unfavourable in the context of the adopted development policies aiming at reducing the existing disparities. In relation to the methodological objective, the results of the conducted research confirm the rationale of the application of the measures of dynamics and the feature variance to determine the character (dynamics and structure) of the socio-economic development process of cities. Comparatively less effective, especially for interpretation, is the application of principal component analysis and a multivariate classification, which is mainly the result of differences in the variance of particular features.

Development of Interethnic Relations in Bosnia and Herzegovina in the First Decades after the Second World War

2018 ◽  
Vol 13 (3-4) ◽  
pp. 87-96
Author(s):  
Elena Yu. Guskova
Keyword(s):  
Ethnic Identity ◽  
Bosnia And Herzegovina ◽  
Second World War ◽  
The State ◽  
World War ◽  
Interethnic Relations ◽  
The Republic ◽  
State Of Affairs ◽  
First Time ◽  
Second World

The article is devoted to the analysis of interethnic relations in Bosnia and Herzegovina (BiH) in the 1940s and 1960s. The article is based on materials from the archives of BiH, Croatia, Slovenia, Yugoslavia. The documents show the state of affairs in the Republic – both in the economy and in ideology. In one or another way, all of them reflect the level of tension in the interethnic relations. For the first time, the article presents the discussion on interethnic relations, on the new phenomenon in multinational Yugoslavia – the emergence of a new people in BiH under the name of “Muslim”. The term “Muslims” is used to define the ethnic identity of Bosniaks in the territory of BiH starting from the 1961 census.

Development of an HPLC-UV Method for Quantification of Stattic

2019 ◽  
Vol 15 (6) ◽  
pp. 568-573
Author(s):  
Soheil Sedaghat ◽  
Ommoleila Molavi ◽  
Akram Faridi ◽  
Ali Shayanfar ◽  
Mohammad Reza Rashidi
Keyword(s):  
High Performance ◽  
Accurate Method ◽  
Plasma Samples ◽  
Promising Target ◽  
Relative Standard ◽  
Dimerization Inhibitor ◽  
Oncogenic Protein ◽  
First Time ◽  
Transcription 3

Background: Signal transducer and activator of transcription 3 (STAT3), an oncogenic protein found constitutively active in many types of human malignancies, is considered to be a promising target for cancer therapy. Objective: In this study for the first time, a simple and accurate method has been developed for the determination of a STAT3 dimerization inhibitor called stattic in aqueous and plasma samples. Methods: A reverse-phase high-performance liquid chromatography (RP-HPLC) composed of C18 column as stationary phase, and the mixture of acetonitrile (60%) and water (40%) as mobile phase with a UV detection at 215 nm were applied for quantification of stattic. The developed method was validated by Food and Drug Administration (FDA) guideline. Results: The method provided a linear range between 1-40 and 2.5-40 µg mL-1 for aqueous and plasma samples, respectively, with a correlation coefficient of 0.999. The accuracy (as recovery) of the developed method was found to be between 95-105% for aqueous medium and 85-115% for plasma samples. The precision (as relative standard deviation) for aqueous and plasma samples was less than 6% and 15%, respectively. The sensitivity of the developed method based on FDA guideline was 1 µg mL-1 for aqueous and 2.5 µg mL-1 for plasma samples. Conclusion: These results show that the established method is a fast and accurate quantification for stattic in aqueous and plasma samples.

Is it necessary to calculate Young’s modulus in AFM nanoindentation experiments regarding biological samples?

2020 ◽  
Vol 12 ◽  
Author(s):  
S.V. Kontomaris ◽  
A. Malamou ◽  
A. Stylianou
Keyword(s):  
Young’S Modulus ◽  
Biological Samples ◽  
Young's Modulus ◽  
Reference Sample ◽  
Nonlinear Behavior ◽  
Accurate Method ◽  
Accurate Solution ◽  
Hertz Model ◽  
Work Done

Background: The determination of the mechanical properties of biological samples using Atomic Force Microscopy (AFM) at the nanoscale is usually performed using basic models arising from the contact mechanics theory. In particular, the Hertz model is the most frequently used theoretical tool for data processing. However, the Hertz model requires several assumptions such as homogeneous and isotropic samples and indenters with perfectly spherical or conical shapes. As it is widely known, none of these requirements are 100 % fulfilled for the case of indentation experiments at the nanoscale. As a result, significant errors arise in the Young’s modulus calculation. At the same time, an analytical model that could account complexities of soft biomaterials, such as nonlinear behavior, anisotropy, and heterogeneity, may be far-reaching. In addition, this hypothetical model would be ‘too difficult’ to be applied in real clinical activities since it would require very heavy workload and highly specialized personnel. Objective: In this paper a simple solution is provided to the aforementioned dead-end. A new approach is introduced in order to provide a simple and accurate method for the mechanical characterization at the nanoscale. Method: The ratio of the work done by the indenter on the sample of interest to the work done by the indenter on a reference sample is introduced as a new physical quantity that does not require homogeneous, isotropic samples or perfect indenters. Results: The proposed approach, not only provides an accurate solution from a physical perspective but also a simpler solution which does not require activities such as the determination of the cantilever’s spring constant and the dimensions of the AFM tip. Conclusion: The proposed, by this opinion paper, solution aims to provide a significant opportunity to overcome the existing limitations provided by Hertzian mechanics and apply AFM techniques in real clinical activities.

The State as an Actor

2017 ◽  
Author(s):  
Georg Menz
Keyword(s):  
Service Sector ◽  
The State ◽  
The Political ◽  
Regulatory Capture ◽  
Banking Institutions ◽  
Political Left ◽  
Central Actor ◽  
Capitalist State ◽  
State Of Affairs ◽  
Rules Of The Game

Despite the state being such a central actor in establishing and policing the rules of the game of any given political economy, its role is often neglected. In this chapter, we briefly review relevant state theories and explore changes to the nature and appearance of the capitalist state. The awesome increase in the political fire power of the financial service sector has unfortunately led to regulatory capture. The state can no longer be considered a neutral umpire, being heavily influenced by the prerogatives of major banking institutions. This state of affairs corrupts the hopes that liberals place in the self-policing powers of the marketplace and reflects certain fears on the political left regarding the pernicious effects of ‘financialization’.

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