Evaluation Of Cognitive Functions With Event-Related Potentials (P300) In Patients With Myotonic Dystrophy

2012 ◽  
Vol 22 (1) ◽  
pp. 49-52
Author(s):  
Bedile İrem Tiftikcioğlu ◽  
Feray Güleç Uyaroğlu ◽  
Yaşar Zorlu
Author(s):  
Vesa Putkinen ◽  
Mari Tervaniemi

Studies conducted during the last three decades have identified numerous differences between musicians and non-musicians in neural correlates of sensory, motor, and higher-order cognitive functions. Research employing event-related potentials/fields has been particularly important in this framework. This chapter reviews the evidence that has emerged from these studies with emphasis on longitudinal studies comparing functional brain development in children taking music lessons and those engaged in non-musical activities. The literature provides empirical and theoretical grounds for concluding that musical training enhances sound encoding skills that are relevant for both music and speech processing. The question whether the benefits of musical training transfer to more distantly related cognitive functions remains controversial, however. Finally, it appears likely that training-induced plasticity alone does not account for the differences in brain function between musicians and non-musicians and, conversely, that predisposing factors also play a role.


Neurosurgery ◽  
2000 ◽  
Vol 47 (2) ◽  
pp. 538-538
Author(s):  
Joseph R. Madsen ◽  
Daniel S. Rizzuto ◽  
Michael Kahana

2004 ◽  
Vol 100 (3) ◽  
pp. 617-625 ◽  
Author(s):  
Wolfgang Heinke ◽  
Ramona Kenntner ◽  
Thomas C. Gunter ◽  
Daniela Sammler ◽  
Derk Olthoff ◽  
...  

Background It is an open question whether cognitive processes of auditory perception that are mediated by functionally different cortices exhibit the same sensitivity to sedation. The auditory event-related potentials P1, mismatch negativity (MMN), and early right anterior negativity (ERAN) originate from different cortical areas and reflect different stages of auditory processing. The P1 originates mainly from the primary auditory cortex. The MMN is generated in or in the close vicinity of the primary auditory cortex but is also dependent on frontal sources. The ERAN mainly originates from frontal generators. The purpose of the study was to investigate the effects of increasing propofol sedation on different stages of auditory processing as reflected in P1, MMN, and ERAN. Methods The P1, the MMN, and the ERAN were recorded preoperatively in 18 patients during four levels of anesthesia adjusted with target-controlled infusion: awake state (target concentration of propofol 0.0 microg/ml), light sedation (0.5 microg/ml), deep sedation (1.5 microg/ml), and unconsciousness (2.5-3.0 microg/ml). Simultaneously, propofol anesthesia was assessed using the Bispectral Index. Results Propofol sedation resulted in a progressive decrease in amplitudes and an increase of latencies with a similar pattern for MMN and ERAN. MMN and ERAN were elicited during sedation but were abolished during unconsciousness. In contrast, the amplitude of the P1 was unchanged by sedation but markedly decreased during unconsciousness. Conclusion The results indicate differential effects of propofol sedation on cognitive functions that involve mainly the auditory cortices and cognitive functions that involve the frontal cortices.


2008 ◽  
Vol 29 (6) ◽  
pp. 488-497 ◽  
Author(s):  
H. Kleinlogel ◽  
Th. Dierks ◽  
Th. Koenig ◽  
H. Lehmann ◽  
A. Minder ◽  
...  

1996 ◽  
Vol 11 (7) ◽  
pp. 357-368 ◽  
Author(s):  
JL Nandrino ◽  
F El Massioui ◽  
J Everett

SummaryOver the past 15 years, researchers have shown an increasing interest in using event-related potentials (ERPs) to study depression. These studies generally fall into four classes: 1), ERPs as a means of detecting depression; 2), ERPs as a tool for distinguishing subtypes of depression; 3), ERPs as a measure of pharmacological effectiveness; 4), ERPs as indicators of defective cognitive operations in depressed subjects. Results from these heterogeneous approaches are often inconsistent and disappointing. Although some ERP components often show increased latencies and diminished amplitudes, these changes seem to reflect principally a variety of non-specific disorders affecting a wide range of cognitive functions rather than a precise and consistent deficit of a particular function. These disappointing results seem to be attributable to methodological problems (heterogeneous patient populations, disproportionate use of the odd-ball paradigm), and do not necessarily call into question the value of studying the ERPs. Furthermore, recent advances in ERP methodology have opened up new perspectives for ERP use in psychopathology.


1987 ◽  
Vol 17 (1-2) ◽  
pp. 1-3 ◽  
Author(s):  
G. Amabile ◽  
G. Pozzessere ◽  
F. Fattapposta ◽  
L. Sanarelli ◽  
E. Valle ◽  
...  

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