scholarly journals Effects of a Short Course of Oral Prednisolone in Patients with Bladder Pain Syndrome with Fluctuating, Worsening Pain despite Low-Dose Triple Therapy

2012 ◽  
Vol 16 (4) ◽  
pp. 175 ◽  
Author(s):  
Hee Jong Jeong
Keyword(s):  
Triple Therapy ◽  
Low Dose ◽  
Pain Syndrome ◽  
Oral Prednisolone ◽  
Bladder Pain Syndrome ◽  
Bladder Pain ◽  
Short Course

scholarly journals Clinical Remission Using Personalized Low-Dose Intravenous Infusions of N-acetylcysteine with Minimal Toxicities for Interstitial Cystitis/Bladder Pain Syndrome

2021 ◽  
Vol 11 (5) ◽  
pp. 342
Author(s):  
Dipnarine Maharaj ◽  
Gayathri Srinivasan ◽  
Sarah Makepeace ◽  
Christopher J. Hickey ◽  
Jacqueline Gouvea
Keyword(s):  
Adverse Events ◽  
Interstitial Cystitis ◽  
Clinical Remission ◽  
Low Dose ◽  
Treatment Options ◽  
Pain Syndrome ◽  
Bladder Pain Syndrome ◽  
Infusion Therapy ◽  
Blurred Vision ◽  
Bladder Pain

Interstitial Cystitis or Bladder Pain Syndrome (IC/BPS) is a heterogeneous condition characterized by elevated levels of inflammatory cytokines, IL-1β, IL-6, IL-8, IL-10, TNF-α, and is associated with debilitating symptoms of pelvic pain and frequent urination. A standard of care for IC/BPS has not been established, and most patients must undergo a series of different treatment options, with potential for severe adverse events. Here, we report a patient with a 26-year history of IC/BPS following treatment with multiple therapies, including low doses of etodolac, amitriptyline and gabapentin, which she was unable to tolerate because of adverse effects, including headaches, blurred vision and cognitive impairment. The patient achieved a complete clinical remission with minimal adverse events after 16 cycles of N-acetylcysteine (NAC) intravenous (IV) infusions over a period of 5 months, and pro-inflammatory cytokine levels were reduced when compared to measurements taken at presentation. Personalized low dose NAC IV infusion therapy represents an effective, safe, anti-inflammatory therapy administered in the outpatient setting for IC/BPS, and warrants further investigation.

scholarly journals Effect of Low-Dose Amitriptyline Treatment for Interstitial Cystitis/Bladder Pain Syndrome

2018 ◽  
Vol 1 (1) ◽  
Author(s):  
Weiguo Chen ◽  
Donghua Xie ◽  
Guolu Liu ◽  
Yifan Chen ◽  
Zongqiang Cai
Keyword(s):  
Interstitial Cystitis ◽  
Low Dose ◽  
Pain Syndrome ◽  
Bladder Pain Syndrome ◽  
Bladder Pain

scholarly journals Daily low dose of tadalafil improves pain and frequency in bladder pain syndrome/interstitial cystitis patients

2022 ◽  
Vol 48 (1) ◽  
pp. 82-87
Author(s):  
Pedro Abreu Mendes ◽  
◽  
Nuno Dias ◽  
Jose Simaes ◽  
Paulo Dinis ◽  
...  
Keyword(s):  
Interstitial Cystitis ◽  
Low Dose ◽  
Pain Syndrome ◽  
Bladder Pain Syndrome ◽  
Bladder Pain

MP07-14 DAILY LOW-DOSE OF TADALAFIL IMPROVES PAIN AND FREQUENCY IN BLADDER PAIN SYNDROME/INTERSTITIAL CYSTITIS PATIENTS

2020 ◽  
Vol 203 ◽  
pp. e101
Author(s):  
Pedro Abreu-Mendes* ◽  
José Simães ◽  
Pedro Pereira ◽  
Dias Nuno ◽  
Francisco Cruz ◽  
...  
Keyword(s):  
Interstitial Cystitis ◽  
Low Dose ◽  
Pain Syndrome ◽  
Bladder Pain Syndrome ◽  
Bladder Pain
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