scholarly journals Correlation between Reproductive Hormonal Level and Osteoporosis among Women in Mongolia

2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Unentsatsral Lkhagvasuren ◽  
Sarantuya Jav ◽  
Battogtokh Zagdsuren
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Rank Order ◽  
Fragility Fractures ◽  
Serum Estradiol ◽  
Mineral Density ◽  
Serum Lh ◽  
Menopausal Women ◽  
The Mean ◽  
Post Menopausal

Background: Postmenopausal osteoporosis is the most common bone metabolic disease associated with low bone mineral density (BMD) and osteopathic fragility fractures, which can lead to significant morbidity. The objective of this study was to investigate the relationship between serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2) levels and bone mineral density (BMD) across the stages of menopause in Mongolian women.Methods: Two hundred sixty participants aged 50.1±4.4 years were enrolled in the study. Blood samples were obtained from each participant and analyzed using ELISA. Data were first stratified and analyzed by bone mineral density status (osteoporotic, osteopenic, and normal) and then by menopause status. Between group differences were analyzed using t-tests, and correlations were assessed using the Spearman rank order test, with Bonferonni correction. The data were analyzed using Statistical Package Statistical Software version 20.0 (SPSS Inc., Chicago, IL). Significance was set at p<0.05.Results: The mean menopausal age was 48.4±3.4, which is comparable to the Mongolian population mean menopausal age. The mean serum estradiol level in the normal BMD group was 18.3±13.1 pg/ml and  15.8±10.7 pg/ml in the osteoporotic group. The mean serum FSH in the normal BMD group was 54.5±44.1 pg/ml and 81.3±34.2 pg/ml in the osteoporotic group. The mean serum LH level in the normal BMD group was 53.1±41.2 and 75.1±26.1 pg/ml in the osteoporotic group. The mean T and Z score were lower in the osteoporotic group. FSH and LH levels significantly differed across menopause stages in that those who were post-menopausal had higher levels compared to those who were pre- or peri-menopausal. Both hormones, FSH and LH, showed weak negative correlations with BMD level, but not E2. There were significant negative correlations between FSH and Speed of Sound (SOS) (r=-0.16; p<0.01), and  between osteoporosis with age (r=-0.30, p<0.05) and number of childbirths (r=-0.14 p<0.05). Discussion: Osteoporosis is a significant problem with associations to hormone levels in post-menopausal women. In our study, mean serum estradiol levels decreased with age, and the mean FSH and LH levels were higher in women of later menopausal stage. Further study is warranted to investigate the bone related studies to establish better statistical references among Mongolian women. 

CORRELATION OF SERUM CHOLESTEROL AND BONE MINERAL DENSITY IN POST MENOPAUSAL WOMEN

2021 ◽  
Vol 5 (12) ◽  
Author(s):  
Sawai Singh ◽  
Lokesh Soni
Keyword(s):  
Bone Mineral Density ◽  
Postmenopausal Women ◽  
Cholesterol Level ◽  
Bone Mineral ◽  
Serum Cholesterol ◽  
Mineral Density ◽  
Menopausal Women ◽  
The Mean ◽  
Group Ii ◽  
Post Menopausal

Background: To find a correlation between serum cholesterol and Bone mineral density in post menopausal women Methods: The study was carried on matched cases and controls. The experimental group consisted of 100 females at postmenopausal age, in which by the DEXA method was diagnosed osteoporosis while the control group consisted of 50 females in a postmenopausal age but without diagnosed osteoporosis who served as controls. Results: Postmenopausal women in the BMI range 18.5 to 25 (normal)were only included in the study. Others were excluded from the study to avoid confounding factors. The mean BMI in women with osteoporosis was 22.13±1.76 and in Group-II was 21.26±2.06. The results were statistically insignificant. Analyzing the average values of serum cholesterol in our study,we found that the mean cholesterol level in group-I was 210.32 ±34.21 mg/dl and 183.21 ±56.32 mg/dl in group-II. The mean cholesterol level was significantly higher in women with osteoporosis. Conclusion: On the decrease in bone mineral density and osteoporosis in postmenopausal women influence many risk factors. Preventive strategies for development of osteoporosis should be initiated in women with elevated serum cholesterol levels. Keywords: Osteoporosis, Menopause, Lipid Profile, BMI.

Bio-impedance and quantitative ultrasound to measure bone mineral density in post-menopausal women from a rural Mexican community

2016 ◽  
Author(s):  
Fernando Blanco-Rodriguez ◽  
Nicole Ellis-Infante ◽  
Victor Lopez-Rivas ◽  
Sherlin May-Kim ◽  
Charlotte Pickett ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Quantitative Ultrasound ◽  
Mineral Density ◽  
Menopausal Women ◽  
Mexican Community ◽  
Post Menopausal ◽  
Measure Bone Mineral Density

scholarly journals Physical Activity Level of Post-menopausal Women with Low Bone Mineral Density

2016 ◽  
Vol 38 (05) ◽  
pp. 225-230 ◽  
Author(s):  
Glauber Dallanezi ◽  
Beatriz Freire ◽  
Eliana Nahás ◽  
Jorge Nahás-Neto ◽  
José Corrente ◽  
...  
Keyword(s):  
Physical Activity ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Physical Activity Level ◽  
Activity Level ◽  
Mineral Density ◽  
Low Bone Mineral Density ◽  
Menopausal Women ◽  
Post Menopausal

Non-weight-bearing effect of trunk and peripheral fat mass on bone mineral density in pre- and post-menopausal women

Maturitas ◽  
2008 ◽  
Vol 60 (3-4) ◽  
pp. 244-247 ◽  
Author(s):  
Akiko Kuwahata ◽  
Yukie Kawamura ◽  
Yukie Yonehara ◽  
Takashi Matsuo ◽  
Ichiro Iwamoto ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Fat Mass ◽  
Weight Bearing ◽  
Mineral Density ◽  
Menopausal Women ◽  
Post Menopausal

93 Does Spinal Bone Mineral Density Predict An Absolute 10 Year Probability of Sustaining A Major Osteoporotic Fracture

2021 ◽  
Vol 50 (Supplement_1) ◽  
pp. i12-i42
Author(s):  
A Nandi ◽  
N Obiechina ◽  
A Timperley ◽  
F Al-Khalidi
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Osteoporotic Fracture ◽  
Negative Correlation ◽  
Pearson Correlation ◽  
Fragility Fractures ◽  
Mineral Density ◽  
Major Osteoporotic Fracture ◽  
T Score ◽  
The Mean

Abstract Introduction Spine and hip bone mineral density (BMD) have previously been shown to predict the risk of sustaining future fractures. Although these have been shown in population studies, there is a paucity of trials looking at the relationship between BMD and 10 year probability of major osteoporotic fractures (Using FRAX UK without BMD) in patients with previous fragility fractures. Aims To evaluate the correlation between spinal T-score and an absolute 10 year probability of sustaining a major osteoporotic fracture (using FRAX without BMD) in patients with prior fragility fractures. Methods A retrospective cross-sectional analysis of 202 patients (29 males and 173 females) with prior fragility fractures attending a fracture prevention clinic between January and August 2019 was performed. Patients with pathological and high impact traumatic fractures were excluded. The BMD at the spine was determined using the lowest T-score of the vertebrae from L1 to L4. Using the FRAX (UK) without BMD, the absolute 10 year probability of sustaining a major osteoporotic fracture was calculated for each patient. Statistical analysis was performed using SPSS 26 software. Results The mean T-score at the spine was −1.15 (SD +/− 1.90) for all patients, −0.68 (SD +/− 0.45) for males and − 1.23 (SD +/− 0.14) for females. The mean FRAX score without BMD for major osteoporotic fracture was 18.5% (SD +/− 8.84) for all patients, 11.41% (SD +/−0.62) and 19.7% (SD +/−0.68) for males and females respectively. Pearson correlation coefficient showed a statistically significant, slightly negative correlation between spinal T- score and the FRAX (UK) without BMD (r = −0.157; p &lt; 0.05). Correlation was not statistically significant when males (r = 0.109; p = 0.59) and females (r = 0.148; p = 0.053) were considered independently. Conclusion In patients with prior fragility fracture spinal BMD has a statistically significant negative correlation with an absolute 10 year probability of sustaining a major osteoporotic fracture.

Carotid plaque and lumbar bone mineral density status in post-menopausal women: An age-matched, analytical cross-sectional study

2019 ◽  
Vol 26 (1) ◽  
pp. 9-18
Author(s):  
Patraporn Sitthisombat ◽  
Sukree Soontrapa ◽  
Srinaree Kaewrudee ◽  
Jen Sothornwit ◽  
Nuntasiri Eamudomkarn ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Cardiovascular Disease ◽  
Lumbar Spine ◽  
Bone Mineral ◽  
Odds Ratio ◽  
Carotid Plaque ◽  
Spine Bone Mineral Density ◽  
Mineral Density ◽  
Menopausal Women ◽  
Post Menopausal

Objective To explore the association between carotid plaque and lumbar spine osteoporosis in post-menopausal women. Study design Age-matched, cross-sectional study. Main outcome measures Carotid plaque and carotid intima media thickness were measured with B-mode ultrasound. Lumbar spine bone mineral density was measured with dual-energy X-ray absorptiometry. Prevalence odds ratios and the respective 95% confidence intervals (95%CI) were calculated to determine the association. Results Seventy-two post-menopausal women with lumbar spine osteoporosis and 72 post-menopausal women with normal lumbar spine bone mineral density were enrolled. The adjusted prevalence odds ratio of carotid plaque presence in post-menopausal women with lumbar spine osteoporosis was 1.73 (95%CI; 0.60 to 4.94) when compared to post-menopausal women with normal lumbar spine bone mineral density. The presence of vulnerable plaque was greater in post-menopausal women with lumbar spine osteoporosis; however, the difference was not statistically significant after adjusting for other risk factors of cardiovascular disease (odds ratio 1.31; 95%CI; 0.39 to 4.43). There was no significant difference in carotid intima media thickness between the two groups. Multiple logistic regression analysis with backward elimination in assessment of potential risk factors for the presence of carotid plaque showed that the year since menopause, family history of cardiovascular disease and systolic blood pressure were nominally significant associated factors with a respective adjusted odds ratio of 1.06 (95%CI; 1.01 to 1.12), 6.23 (95%CI; 1.65 to 23.46) and 1.03 (95%CI; 1.01 to 1.06). Conclusions The current study indicates that lumbar spine osteoporosis is not associated with the presence of carotid plaque, whereas year since menopause, family history of cardiovascular disease and systolic blood pressure are associated factors.

Dose‐response effects of exercise on bone mineral density and content in post‐menopausal women

2019 ◽  
Vol 29 (8) ◽  
pp. 1121-1129 ◽  
Author(s):  
Paola Gonzalo‐Encabo ◽  
Jessica McNeil ◽  
Devon J. Boyne ◽  
Kerry S. Courneya ◽  
Christine M. Friedenreich
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Dose Response ◽  
Mineral Density ◽  
Menopausal Women ◽  
Post Menopausal
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