The relationship between inhibitors of the Wnt signalling pathway (Dickkopf-1(DKK1) and sclerostin), bone mineral density, vascular calcification and arterial stiffness in post-menopausal women

Bone ◽  
2013 ◽  
Vol 56 (1) ◽  
pp. 42-47 ◽  
Author(s):  
Geeta Hampson ◽  
Sylvie Edwards ◽  
Soraya Conroy ◽  
Glen M. Blake ◽  
Ignac Fogelman ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Arterial Stiffness ◽  
Vascular Calcification ◽  
Bone Mineral ◽  
Signalling Pathway ◽  
Mineral Density ◽  
Menopausal Women ◽  
Post Menopausal ◽  
The Relationship ◽  
Dickkopf 1

The relationship between plasma homocysteine levels and bone mineral density in post-menopausal women

2010 ◽  
Vol 21 (4) ◽  
pp. 301-305 ◽  
Author(s):  
Paolo Bucciarelli ◽  
Giuseppe Martini ◽  
Ida Martinelli ◽  
Elena Ceccarelli ◽  
Luigi Gennari ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Plasma Homocysteine ◽  
Mineral Density ◽  
Menopausal Women ◽  
Post Menopausal ◽  
The Relationship

Polyunsaturated fatty acids and their relationship with bone mineral density and markers of bone turnover in post-menopausal women

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
O. Feehan ◽  
M.M. Slevin ◽  
P.J. Allsopp ◽  
P.J. Magee ◽  
L.K. Pourshahidi ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Resorption ◽  
Bone Turnover ◽  
Bone Mineral ◽  
Mineral Density ◽  
Menopausal Women ◽  
Turnover Markers ◽  
Total Body ◽  
Post Menopausal ◽  
The Relationship

AbstractAge-related bone loss leads to a significant decline in bone formation and an increase in bone resorption resulting in a marked negative effect on bone mineral density (BMD). This bone turnover cycle can be further disrupted by estrogen deficiency during menopause which can lead to a great net loss of bone in post-menopausal women. Evidence suggests that n-3 polyunsaturated fatty acids (PUFA) may have a beneficial effect on the inflammatory regulation of bone remodelling and thus reducing bone loss. This study investigated the relationship between PUFA status, total body bone mineral density (BMD) and bone turnover markers in a cohort of post-menopausal women in Northern Ireland. Total body T-score and BMD were measured using dual energy x-ray absorptiometry (DEXA) in 300 non-osteoporotic post-menopausal women (45–75 years). The bone turnover markers serum osteocalcin, alkaline phosphatase, C-terminal telopeptides of type 1 collagen (CTX) and urinary deoxypyridinoline (DPD) were quantified. Total n6 PUFA (LA + AA) and n3 PUFA (ALA + EPA + DPA + DHA) were measured in serum using gas chromatography mass spectrometry. Total n3:n6 ratio was calculated. Dietary intake and lifestyle factors were determined by 4 day food diary and questionnaire, respectively. Spearman rank correlation analysis were conducted to investigate the relationship between PUFA and total body BMD. Secondary analysis investigated the relationship between PUFA and the bone turnover markers. Median (IQR) age was 61 (10) years, body mass index 27 (6) kg/m2, total body BMD, 1.3 (0.11) g/cm2 and age at menopause was 50 (6) years. Total median (IQR) serum n-3 PUFA status was 0.231 (0.128) mg/mL, total n6 PUFA was 1.248 (0.477) mg/mL and the n6:n3 PUFA ratio was 5.82 (2.63). Median (IQR) daily fish consumption was 25 (46) grams, calcium 702 (364) mg and vitamin D 2.21 (2.3) μg. There was no significant correlation between markers of total n3, n6, n6:n3 ratio and total body T-score, BMD or bone mineral content. PUFA was not significantly associated with total body BMD. There was a significant negative correlation between the urinary bone resorption marker DPD and total n3 PUFA (r = -0.137, P = 0018); EPA (r = -0.150, P = 0.009), and DPA (r = -0.118, P = 0.042). A significant negative correlation was observed between urinary CTX and the n-6 PUFA AA (r = -0.121, P = 0.036), the n3 PUFA ALA (r = -0.123, P = 0.033). PUFA were associated with less bone resorption therefore it is plausible that PUFA have a positive anti-inflammatory effect on bone resorption and warrants further investigation.

Bio-impedance and quantitative ultrasound to measure bone mineral density in post-menopausal women from a rural Mexican community

2016 ◽  
Author(s):  
Fernando Blanco-Rodriguez ◽  
Nicole Ellis-Infante ◽  
Victor Lopez-Rivas ◽  
Sherlin May-Kim ◽  
Charlotte Pickett ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Quantitative Ultrasound ◽  
Mineral Density ◽  
Menopausal Women ◽  
Mexican Community ◽  
Post Menopausal ◽  
Measure Bone Mineral Density

scholarly journals Physical Activity Level of Post-menopausal Women with Low Bone Mineral Density

2016 ◽  
Vol 38 (05) ◽  
pp. 225-230 ◽  
Author(s):  
Glauber Dallanezi ◽  
Beatriz Freire ◽  
Eliana Nahás ◽  
Jorge Nahás-Neto ◽  
José Corrente ◽  
...  
Keyword(s):  
Physical Activity ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Physical Activity Level ◽  
Activity Level ◽  
Mineral Density ◽  
Low Bone Mineral Density ◽  
Menopausal Women ◽  
Post Menopausal

Non-weight-bearing effect of trunk and peripheral fat mass on bone mineral density in pre- and post-menopausal women

Maturitas ◽  
2008 ◽  
Vol 60 (3-4) ◽  
pp. 244-247 ◽  
Author(s):  
Akiko Kuwahata ◽  
Yukie Kawamura ◽  
Yukie Yonehara ◽  
Takashi Matsuo ◽  
Ichiro Iwamoto ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Fat Mass ◽  
Weight Bearing ◽  
Mineral Density ◽  
Menopausal Women ◽  
Post Menopausal
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