scholarly journals ETIOLOGY AND RISK FACTORS FOR ESOPHAGEAL CARCINOMA

2013 ◽  
Author(s):  
Sule Karadayi ◽  
Alper Findikcioglu
2010 ◽  
Vol 28 (4-5) ◽  
pp. 641-644 ◽  
Author(s):  
Lars R. Lundell

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Jun Tang ◽  
Jian-zhu Zhao ◽  
Kai-ming Ren ◽  
Fu-shuang Zheng ◽  
Xi-wen Wang ◽  
...  

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Ruzhen Jia ◽  
Qinsong Luan ◽  
Jing Wang ◽  
Dongsheng Hou ◽  
Shulei Zhao

In order to predict related risk factors for lymph node metastasis (LNM) in patients with superficial esophageal carcinoma (SEC) and provide reference for endoscopic minimally invasive treatment, we included a total of 93 patients with superficial esophageal carcinoma who have underwent esophagectomy and lymph node dissection from 2010 to 2015. The depth of invasion was remeasured and classified into 6 groups according to their wall penetration. The prediction model was founded based on the independent risk factors. The results shows that lymph node metastasis of m1, m2, m3, sm1, sm2, and sm3 of superficial esophageal carcinoma was 0%, 0%, 5.3%, 8.7%, 17.6%, and 37.5%, respectively. The tumor size, differentiation, and lymphvascular invasion were also significantly related to lymph node metastasis by univariate analysis. Multivariate analysis showed that the depth of invasion and lymphovascular invasion were independent risk factors of lymph node metastasis. A prediction model for lymph node metastasis was established as follows: p=ex/(1+ex), and x = −5.469 + 0.839 × depth of invasion + 1.992 × lymphavascular metastasis. The area under ROC curve was 0.858 (95% CI: 0.757–0.959). It was also shown that the depth of invasion was related to tumor differentiation, macroscopic type, and tumor size.


2020 ◽  
Vol 40 (2) ◽  
pp. 1071-1077
Author(s):  
NATSUKO SATOMI-TSUSHITA ◽  
YOSHITAKA HONMA ◽  
KENGO NAGASHIMA ◽  
YOSHINORI ITO ◽  
HIDEKAZU HIRANO ◽  
...  

2018 ◽  
Vol Volume 11 ◽  
pp. 2311-2317 ◽  
Author(s):  
Yang Zhang ◽  
Zongjuan Li ◽  
Wei Zhang ◽  
Wei Chen ◽  
Yipeng Song

2020 ◽  
Vol 26 (6) ◽  
pp. 670-685
Author(s):  
Yun-Gang Luo ◽  
Li-Wei Duan ◽  
Xuan Ji ◽  
Wen-Yuan Jia ◽  
Yun Liu ◽  
...  

Endoscopy ◽  
2014 ◽  
Vol 46 (08) ◽  
pp. 640-644 ◽  
Author(s):  
Qiang Shi ◽  
Hui Ju ◽  
Li-Qing Yao ◽  
Ping-Hong Zhou ◽  
Mei-Dong Xu ◽  
...  

2017 ◽  
Vol 35 (4_suppl) ◽  
pp. 190-190
Author(s):  
Natsuko Tsushita ◽  
Yoshitaka Honma ◽  
Kengo Nagashima ◽  
Takahiro Miyamoto ◽  
Shoko Nakamura ◽  
...  

190 Background: Severe benign cicatricial stricture (SBCS) is a major complication after chemoradiotherapy (CRT) for esophageal carcinoma (EC), and causes oral intake impairment leading to deterioration of quality of life even after being cured. Aim of this study was to investigate risk factors of SBCS. Methods: The subjects of this study were patients with stage II/III (T3) EC who received CRT and achieved complete response (CR) between 2000 and 2011. SBCS was determined as disability of passage by diameter-9mm endoscope. Results: Among 197 patients with Stage II/III (T3) treated by CRT, CR was obtained in 91 patients, who were included in this analysis. The median age was 63 years. Fifteen patients (16.5%) were female. The median follow-up time was 5.1 years. The cumulative incidence of SBCS was 15.0% (95%CI 9.0-24.5). Significant risk factors of SBCS were female (hazard ratio (HR) 3.3 (95%CI 1.1-10.0), p = 0.04), requirement of diced/liquid meal (HR 5.7 (95%CI 1.8-18.2), p = 0.003), tumor occupying 3/4 or grater of esophageal perimeter (HR 7.4 (95%CI 1.3-42.9), p = 0.03) and disability of endoscope passage (HR 12.7 (95%CI 4.2-38.5), p < 0.001) in univariate analysis. Hypoalbuminemia increased the risk of SBCS (HR 2.4 (95%CI 0.8-7.1), p = 0.12) marginally. As for the factors during CRT, grade 2-4 esophagitis significantly increased the risk of SBCS (HR 6.2 (95%CI 1.5-25.7), p = 0.01). Multivariate analysis showed that hypoalbuminemia (HR 3.5 (95%CI 1.1-11.1), p = 0.03) and disability of endoscope passage (HR 14.8 (95%CI 4.3-51.3), p < 0.001) were the significant risk factors of SBCS. Female (HR 1.5 (95%CI 0.5-4.9), p = 0.51) was not a significant risk factor in multivariate analysis. Conclusions: Obstructions before CRT, hypoalbuminemia and severe esophagitis during CRT are considered as risk factors of SBCS. Because SBCS occurred after completion of CRT, prophylactic treatment should be established especially for esophageal carcinoma patients with risk factors of SBCS.


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