scholarly journals Risk factors for esophageal fistula in patients with locally advanced esophageal carcinoma receiving chemoradiotherapy

2018 ◽  
Vol Volume 11 ◽  
pp. 2311-2317 ◽  
Author(s):  
Yang Zhang ◽  
Zongjuan Li ◽  
Wei Zhang ◽  
Wei Chen ◽  
Yipeng Song
Keyword(s):  
Risk Factors ◽  
Esophageal Carcinoma ◽  
Locally Advanced ◽  
Esophageal Fistula

scholarly journals Risk Factors for Esophageal Fistula Associated With Chemoradiotherapy for Locally Advanced Unresectable Esophageal Cancer

Medicine ◽  
2016 ◽  
Vol 95 (20) ◽  
pp. e3699 ◽  
Author(s):  
Takahiro Tsushima ◽  
Junki Mizusawa ◽  
Kazuki Sudo ◽  
Yoshitaka Honma ◽  
Ken Kato ◽  
...  
Keyword(s):  
Risk Factors ◽  
Esophageal Cancer ◽  
Locally Advanced ◽  
Esophageal Fistula

scholarly journals Pharyngocutaneous Fistulas Following Total Laryngectomy

2021 ◽  
Author(s):  
Alexandru Nicolaescu ◽  
Șerban V.G. Berteșteanu ◽  
Raluca Grigore ◽  
Mihnea Cojocărița-Condeescu ◽  
Bogdan Popescu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Total Laryngectomy ◽  
Locally Advanced ◽  
Esophageal Fistula ◽  
Vocal Rehabilitation ◽  
Multiple Factors ◽  
Concomitant Factors ◽  
Prolong Hospital Stay

Total laryngectomy is still the final therapeutic solution in cases of locally advanced laryngeal cancer, as well as in cases of therapeutic failure of organ-sparing surgery or radiation therapy. Following excision of the larynx, the remaining pharynx is reconstructed to obtain continuity of the upper digestive tract. One of the most common complications in these patients, despite constant refinement of the procedure, is the development of a pharyngo-cutaneous fistula. These fistulas prolong hospital stay and often require a second surgical procedure, increasing morbidity and cost for the patient, while diminishing his quality of life. Some risk-factors have been identified, but only some may be corrected before surgery to lower this risk. Managing the fistula once present depends on multiple factors, essential being the size of the fistula as well as the position and concomitant factors, with options ranging from conservative measures to aggressive reconstructive surgery with local miocutaneous flaps. Modern vocal rehabilitation with T.E.P. (tracheo-esophageal puncture) and vocal prosthesis placement presents a new challenge – because of the risk of developing a tracheo-esophageal fistula, with an even higher risk for the patient because of tracheal aspiration. Understanding healing mechanisms of these structures is key to proper management of this complication.

Locally Advanced Esophageal Carcinoma: Is There Still a Role of Surgery Alone Without Neoadjuvant Treatment?

2015 ◽  
Vol 19 (4) ◽  
pp. 587-593 ◽  
Author(s):  
Matthias Reeh ◽  
Michael F. Nentwich ◽  
Samir Asani ◽  
Faik G. Uzunoglu ◽  
Maximilian Bockhorn ◽  
...  
Keyword(s):  
Esophageal Carcinoma ◽  
Locally Advanced ◽  
Neoadjuvant Treatment

scholarly journals A CROSS-SECTIONAL STUDY ON THE PREVALANCE AND RISK FACTORS OF LYMPHOEDEMA IN CARCINOMA BREAST

2017 ◽  
Vol 10 (6) ◽  
pp. 240
Author(s):  
Vishnu Gopal ◽  
Abhinabha Acharya ◽  
Vasudha Narayanaswamy ◽  
Santanu Pal
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Breast Carcinoma ◽  
Upper Limb ◽  
Cancer Care ◽  
Postoperative Radiotherapy ◽  
Care Center ◽  
Locally Advanced ◽  
Significant Risk ◽  
Axillary Lymph

Objectives: Lymphedema of the arm is a devastating complication of breast carcinoma treatment. There is a lack of research on the risk factors and methods of preventing upper limb lymphedema after breast carcinoma treatment. The aims of the study are to identify the prevalence and risk factors for upper limb lymphedema in patients attending a tertiary cancer care center in India. Methods: 199 patients who attended the outpatient department of radiotherapy of IPGMER and SSKM, after undergoing surgical treatment for breast cancer between November 2014 to May 2016 were examined for the presence of lymphedema and its risk factors were analyzed. Lymphedema was defined as being present when there is an increase of >5% sum difference in the arm circumferences measured at different levels of both the upper limbs. Results: Of the 199 patients analyzed, 85 (42.7%) patients were found to have lymphedema. The prevalence of lymphedema was 25% in those who underwent surgery alone and 54% in those who underwent chest wall radiotherapy also. Locally advanced stage of the disease, body mass index >25 kg/m2, number of lymph nodes removed during surgery, and adjuvant radiotherapy were found to be significant risk factors for the development of lymphedema. Conclusion: Based on the results of this study, we recommend weight reduction and more judicious axillary lymph node dissection and use of postoperative radiotherapy as methods to prevent breast cancer-associated lymphedema in the tertiary cancer care centers in India.

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