scholarly journals T1 mapping and magnetic resonance elastography: potential new techniques for quantification of parenchymal changes in hepatic amyloidosis

2017 ◽  
Vol 23 (6) ◽  
pp. 478-478 ◽  
Author(s):  
Elif Peker ◽  
Ayse Erden
Keyword(s):  
Magnetic Resonance ◽  
T1 Mapping ◽  
Magnetic Resonance Elastography ◽  
New Techniques ◽  
Hepatic Amyloidosis

scholarly journals Hepatic Amyloidosis with an Extremely High Stiffness Value on Magnetic Resonance Elastography

2016 ◽  
Vol 15 (3) ◽  
pp. 251-252 ◽  
Author(s):  
Shuya MATSUDA ◽  
Utaroh MOTOSUGI ◽  
Ryo KATO ◽  
Masaru MURAOKA ◽  
Yuichiro SUZUKI ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Elastography ◽  
High Stiffness ◽  
Hepatic Amyloidosis

Assessment of liver T1 mapping in fontan patients and its correlation with magnetic resonance elastography-derived liver stiffness

2019 ◽  
Vol 44 (7) ◽  
pp. 2403-2408 ◽  
Author(s):  
Preeti Ramachandran ◽  
Suraj D. Serai ◽  
Gruschen R. Veldtman ◽  
Sean M. Lang ◽  
Wojciech Mazur ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
T1 Mapping ◽  
Liver Stiffness ◽  
Magnetic Resonance Elastography ◽  
Fontan Patients

scholarly journals Magnetic Resonance Elastography of Liver in Light Chain Amyloidosis

2019 ◽  
Vol 8 (5) ◽  
pp. 739 ◽  
Author(s):  
Sudhakar K. Venkatesh ◽  
Safa Hoodeshenas ◽  
Sandeep H. Venkatesh ◽  
Angela Dispenzieri ◽  
Morie A. Gertz ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Correlation Analysis ◽  
Partial Correlation ◽  
Pearson Correlation ◽  
Liver Volume ◽  
Liver Stiffness ◽  
Amyloid Deposition ◽  
Magnetic Resonance Elastography ◽  
Hepatic Amyloidosis ◽  
Pearson Correlation Analysis

In this paper, we present our preliminary findings regarding magnetic resonance elastography (MRE) on the livers of 10 patients with systemic amyloidosis. Mean liver stiffness measurements (LSM) and spleen stiffness measurements (SSM) were obtained. Magnetic resonance imaging (MRI) images were analyzed for the distribution pattern of amyloid deposition. Pearson correlation analysis was performed in order to study the correlation between LSM, SSM, liver span, liver volume, spleen span, spleen volume, serum alkaline phosphatase (ALP), N-terminal pro b-type natriuretic peptide (NT pro BNP), and the kappa and lambda free light chains. An increase in mean LSM was seen in all patients. Pearson correlation analysis showed a statistically significant correlation between LSM and liver volume (r = 0.78, p = 0.007) and kappa chain level (r = 0.65, p = 0.04). Interestingly, LSM did not correlate significantly with SSM (r = 0.45, p = 0.18), liver span (r = 0.57, p = 0.08), or serum ALP (r = 0.60, p = 0.07). However, LSM correlated significantly with serum ALP when corrected for liver volume (partial correlation, r = 0.71, p = 0.03) and NT pro BNP levels (partial correlation, r = 0.68, p = 0.04). MRI review revealed that amyloid deposition in the liver can be diffuse, lobar, or focal. MRE is useful for the evaluation of hepatic amyloidosis and shows increased stiffness in hepatic amyloidosis. MRE has the potential to be a non-invasive quantitative imaging marker for hepatic amyloidosis.

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