scholarly journals Fibroadenoma versus phyllodes tumor: distinguishing factors in patients diagnosed with fibroepithelial lesions after a core needle biopsy

2014 ◽  
Author(s):  
C. Wiratkapun ◽  
P. Piyapan ◽  
P. Lertsithichai ◽  
N. Larbcharoensub
Keyword(s):  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Phyllodes Tumor ◽  
Core Needle

Factors associated with phyllodes tumor of the breast after core needle biopsy identifies fibroepithelial neoplasm

2012 ◽  
Vol 178 (1) ◽  
pp. 299-303 ◽  
Author(s):  
Daniel J. Gould ◽  
Jessica A. Salmans ◽  
Brian K. Lassinger ◽  
Alejandro Contreras ◽  
Carolina Gutierrez ◽  
...  
Keyword(s):  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Phyllodes Tumor ◽  
Core Needle ◽  
Factors Associated

Phyllodes Tumors

2017 ◽  
Author(s):  
Tina J Hieken ◽  
Rafael E Jimenez
Keyword(s):  
High Risk ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Phyllodes Tumor ◽  
Oncologic Outcomes ◽  
Breast Adenocarcinoma ◽  
Adjuvant Radiation ◽  
Core Needle ◽  
Phyllodes Tumors ◽  
Stromal Component

Phyllodes tumors are rare primary breast neoplasms graded as benign, borderline, or malignant based on pathology characterization of the stromal component. Core-needle biopsy is recommended as the first diagnostic step for breast lesions suspicious for phyllodes. Surgical excisional biopsy is recommended for a core-needle biopsy showing cellular fibroepithelial lesion or a mass suspicious for phyllodes tumor as pathology diagnosis is challenging, especially on limited tissue specimens. Surgical treatment parallels that for soft tissue sarcoma rather than breast adenocarcinoma. Wide local excision and mastectomy, with 1 cm tumor-free margins, provide equivalent oncologic outcomes. Tumor enucleation, subtotal resection, and positive final margins should be avoided. Axillary surgery is not recommended as lymph node metastases are rare. Adjuvant radiation is not recommended as routine, nor is adjuvant chemotherapy, although either or both may be considered for primary or recurrent high-risk malignant phyllodes tumors on a case-by-case basis. Local recurrence rates are influenced by margin status and tumor grade. Distant metastases occur in up to 25% of patients with borderline/malignant tumors and bestow a poor prognosis. Recent molecular genetic analyses of phyllodes tumors have identified potentially targetable mutations that may guide future therapy for high-risk, recurrent, or metastatic phyllodes tumors. This review contains 5 figures, 5 tables, and 53 references. Key words: biomarkers, breast sarcoma, diagnosis, outcomes, pathology, phyllodes tumor, surgery, treatment

scholarly journals Can We Predict Phyllodes Tumor among Fibroepithelial Lesions with Cellular Stroma Diagnosed at Breast Core Needle Biopsy?

2011 ◽  
Vol 64 (6) ◽  
pp. 603 ◽  
Author(s):  
Hae Kyoung Jung ◽  
Kyung Hee Ko ◽  
Ji Young Rho ◽  
Hee Jung Moon ◽  
Eun-Kyung Kim ◽  
...  
Keyword(s):  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Phyllodes Tumor ◽  
Core Needle

Phyllodes Tumors

2017 ◽  
Author(s):  
Tina J Hieken ◽  
Rafael E Jimenez
Keyword(s):  
High Risk ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Phyllodes Tumor ◽  
Oncologic Outcomes ◽  
Breast Adenocarcinoma ◽  
Adjuvant Radiation ◽  
Core Needle ◽  
Phyllodes Tumors ◽  
Stromal Component

Phyllodes tumors are rare primary breast neoplasms graded as benign, borderline, or malignant based on pathology characterization of the stromal component. Core-needle biopsy is recommended as the first diagnostic step for breast lesions suspicious for phyllodes. Surgical excisional biopsy is recommended for a core-needle biopsy showing cellular fibroepithelial lesion or a mass suspicious for phyllodes tumor as pathology diagnosis is challenging, especially on limited tissue specimens. Surgical treatment parallels that for soft tissue sarcoma rather than breast adenocarcinoma. Wide local excision and mastectomy, with 1 cm tumor-free margins, provide equivalent oncologic outcomes. Tumor enucleation, subtotal resection, and positive final margins should be avoided. Axillary surgery is not recommended as lymph node metastases are rare. Adjuvant radiation is not recommended as routine, nor is adjuvant chemotherapy, although either or both may be considered for primary or recurrent high-risk malignant phyllodes tumors on a case-by-case basis. Local recurrence rates are influenced by margin status and tumor grade. Distant metastases occur in up to 25% of patients with borderline/malignant tumors and bestow a poor prognosis. Recent molecular genetic analyses of phyllodes tumors have identified potentially targetable mutations that may guide future therapy for high-risk, recurrent, or metastatic phyllodes tumors. This review contains 5 figures, 5 tables, and 53 references. Key words: biomarkers, breast sarcoma, diagnosis, outcomes, pathology, phyllodes tumor, surgery, treatment

Cellular fibroepithelial lesions diagnosed on core needle biopsy: Is there any role of clinical‐sonography features helping to differentiate fibroadenomas and phyllodes tumor?

2020 ◽  
Vol 122 (3) ◽  
pp. 382-387
Author(s):  
Basma Al‐Arnawoot ◽  
Anabel Scaranelo ◽  
Rachel Fleming ◽  
Supriya Kulkarni ◽  
Ravi J. Menezes ◽  
...  
Keyword(s):  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Phyllodes Tumor ◽  
Core Needle

P977 Core needle biopsy as a diagnostic of phyllodes tumor and fibroadenoma

2009 ◽  
Vol 107 ◽  
pp. S688-S688
Author(s):  
P. Amaral ◽  
D. Calvano ◽  
M. Ricci ◽  
L. Pompei ◽  
J. Filassi ◽  
...  
Keyword(s):  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Phyllodes Tumor ◽  
Core Needle

scholarly journals Recurrent Mastitis after Core Needle Biopsy: Case Report of an Unusual Complication after Core Needle Biopsy of a Phyllodes Tumor

Breast Care ◽  
2012 ◽  
Vol 7 (3) ◽  
pp. 240-244 ◽  
Author(s):  
Nikola Kasprowicz ◽  
Gerd J. Bauerschmitz ◽  
Alexandra Schönherr ◽  
Stephan E. Baldus ◽  
Wolfgang Janni ◽  
...  
Keyword(s):  
Case Report ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Phyllodes Tumor ◽  
Unusual Complication ◽  
Core Needle

scholarly journals Significant Histologic Features Differentiating Cellular Fibroadenoma From Phyllodes Tumor on Core Needle Biopsy Specimens

2014 ◽  
Vol 142 (3) ◽  
pp. 362-369 ◽  
Author(s):  
Saba Yasir ◽  
Roberto Gamez ◽  
Sarah Jenkins ◽  
Daniel W. Visscher ◽  
Aziza Nassar
Keyword(s):  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Phyllodes Tumor ◽  
Core Needle ◽  
Biopsy Specimens

Differentiation Between Phyllodes Tumor and Fibroadenoma Using Real-Time Elastography

2011 ◽  
Vol 32 (S 02) ◽  
pp. E75-E79 ◽  
Author(s):  
B. Adamietz ◽  
L. Kahmann ◽  
P. Fasching ◽  
R. Schulz-Wendtland ◽  
M. Uder ◽  
...  
Keyword(s):  
Real Time ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Phyllodes Tumor ◽  
Breast Lesions ◽  
Rare Entity ◽  
Core Needle ◽  
Malignancy Rate ◽  
Phyllodes Tumors ◽  
Elastic Characteristics

Abstract Purpose: Phyllodes tumors (PT) are a rare entity accounting for less than 1 % of all breast lesions. They have a malignancy rate of 25 – 30 %. Differentiation from benign fibroadenomas is difficult using ultrasound, mammogram and MRI. The elastic characteristics of both tumors were examined using real-time elastography (RTE) to find specific patterns that make differentiation possible. Materials and Methods: From February 2007 to May 2009, a total of 620 women were examined by RTE. Histological diagnosis was achieved using core needle biopsy. 123 of the lesions were fibroadenomas, 8 were phyllodes tumors. All patients underwent mammography and ultrasound followed by RTE. Sonography was performed by Acuson Antares, Premium Edition® (Siemens, Erlangen, Germany) with a 7 and 10 MHz transducer. Results: All phyllodes tumors had a similar elastic pattern with an elastic center and inelastic outer limits, referred to as the “ring sign”. It was found in 5 % of all fibroadenomas. Conclusion: RTE provides a specific elastic pattern, which is sufficient for differentiating between a fibroadenoma and a phyllodes tumor. Therefore, the detection of the most suspicious lesion in women with the coexistence of multiple fibroadenomas and phyllodes tumors seems easier.

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