Estimation of Hippocampus Volume from MRI Using ImageJ for Alzheimer’s Diagnosis

2011 ◽  
pp. 15-20 ◽  
Author(s):  
LS Jaba ◽  
V Shanthi ◽  
DJ Singh
Keyword(s):  
Hippocampus Volume

P3-058 MRI-defined hippocampus volume predicts conversion to AD in cognitively impaired patients without dementia

2004 ◽  
Vol 25 ◽  
pp. S367
Author(s):  
D.P. Devanand ◽  
Gnani Pratap ◽  
Alexander Khandji ◽  
Matthias H. Tabert ◽  
Gregory H. Pelton ◽  
...  
Keyword(s):  
Cognitively Impaired ◽  
Hippocampus Volume

scholarly journals Structural Analysis of Brain Hub Region Volume and Cortical Thickness in Patients with Mild Cognitive Impairment and Dementia

Medicina ◽  
2020 ◽  
Vol 56 (10) ◽  
pp. 497
Author(s):  
Nauris Zdanovskis ◽  
Ardis Platkājis ◽  
Andrejs Kostiks ◽  
Guntis Karelis
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Entorhinal Cortex ◽  
Cortical Thickness ◽  
Test Scores ◽  
Cognitive Assessment ◽  
Significant Positive Correlation ◽  
Hippocampal Volume ◽  
Positive Correlation ◽  
Hippocampus Volume

Background and Objectives: A complex network of axonal pathways interlinks the human brain cortex. Brain networks are not distributed evenly, and brain regions making more connections with other parts are defined as brain hubs. Our objective was to analyze brain hub region volume and cortical thickness and determine the association with cognitive assessment scores in patients with mild cognitive impairment (MCI) and dementia. Materials and Methods: In this cross-sectional study, we included 11 patients (5 mild cognitive impairment; 6 dementia). All patients underwent neurological examination, and Montreal Cognitive Assessment (MoCA) test scores were recorded. Scans with a 3T MRI scanner were done, and cortical thickness and volumetric data were acquired using Freesurfer 7.1.0 software. Results: By analyzing differences between the MCI and dementia groups, MCI patients had higher hippocampal volumes (p < 0.05) and left entorhinal cortex thickness (p < 0.05). There was a significant positive correlation between MoCA test scores and left hippocampus volume (r = 0.767, p < 0.01), right hippocampus volume (r = 0.785, p < 0.01), right precuneus cortical thickness (r = 0.648, p < 0.05), left entorhinal cortex thickness (r = 0.767, p < 0.01), and right entorhinal cortex thickness (r = 0.612, p < 0.05). Conclusions: In our study, hippocampal volume and entorhinal cortex showed significant differences in the MCI and dementia patient groups. Additionally, we found a statistically significant positive correlation between MoCA scores, hippocampal volume, entorhinal cortex thickness, and right precuneus. Although other brain hub regions did not show statistically significant differences, there should be additional research to evaluate the brain hub region association with MCI and dementia.

Are there any gender differences in the hippocampus volume after head-size correction? A volumetric and voxel-based morphometric study

2014 ◽  
Vol 570 ◽  
pp. 119-123 ◽  
Author(s):  
Gabor Perlaki ◽  
Gergely Orsi ◽  
Eniko Plozer ◽  
Anna Altbacker ◽  
Gergely Darnai ◽  
...  
Keyword(s):  
Gender Differences ◽  
Head Size ◽  
Morphometric Study ◽  
Size Correction ◽  
Hippocampus Volume

scholarly journals Hippocampus volume and episodic memory in schizophrenia

2009 ◽  
Vol 15 (2) ◽  
pp. 182-195 ◽  
Author(s):  
ROBERT J. THOMA ◽  
MOLLIE MONNIG ◽  
FAITH M. HANLON ◽  
GREGORY A. MILLER ◽  
HELEN PETROPOULOS ◽  
...  
Keyword(s):  
Episodic Memory ◽  
Verbal Memory ◽  
Visual Memory ◽  
Chronic Schizophrenia ◽  
Magnetic Resonance Images ◽  
Schizophrenia Group ◽  
Positive Correlations ◽  
The Relationship ◽  
Hippocampus Volume ◽  
Volumetric Measures

AbstractPrevious studies of schizophrenia have suggested a linkage between neuropsychological (NP) deficits and hippocampus abnormality. The relationship between hippocampus volume and NP functioning was investigated in 24 patients with chronic schizophrenia and 24 matched healthy controls. Overall intracranial, white and gray matter, and anterior (AH) and posterior (PH) hippocampus volumes were assessed from magnetic resonance images (MRI). NP domains of IQ, attention, and executive function were also evaluated with respect to volumetric measures. It was hypothesized that AH and PH volumes and episodic memory scores would be positively associated in controls and that the schizophrenia group would depart from this normative pattern. NP functioning was impaired overall and AH volume was smaller in the schizophrenia group. In the controls, the hippocampus–memory relationships involved AH and PH, and correlations were significant for verbal memory measures. In the schizophrenia group, positive correlations were constrained to PH. Negative correlations emerged between AH and verbal and visual memory measures. For both groups, cortical volume negatively correlated with age, but a negative correlation between age and hippocampus volume was found only in the schizophrenia group. In this sample of adults with schizophrenia, atypical relationships between regional hippocampus volumes and episodic memory ability were found, as was an atypical negative association between hippocampus volume and age. (JINS, 2009, 15, 182–195.)

Cognitive and clinical correlates of hippocampus volume, an MRI 2-year follow-up study

2014 ◽  
Vol 35 (1) ◽  
pp. 22
Author(s):  
Mamdoh El Gamal ◽  
Rasha Bassim ◽  
MohamedSamer Abdelaal ◽  
Maha ELTayebani
Keyword(s):  
Clinical Correlates ◽  
Follow Up Study ◽  
Hippocampus Volume

P2-156: EFFECTS OF LEPTIN ON HIPPOCAMPUS VOLUME AND COGNITIVE PERFORMANCE

2006 ◽  
Vol 14 (7S_Part_13) ◽  
pp. P727-P728
Author(s):  
Sebastian Huhn ◽  
Frauke Beyer ◽  
Rui Zhang ◽  
Leonie Lampe ◽  
Tobias Luck ◽  
...  
Keyword(s):  
Cognitive Performance ◽  
Hippocampus Volume

Longitudinal MR study of brain structure and hippocampus volume in major depressive disorder

2011 ◽  
Vol 123 (3) ◽  
pp. 211-219 ◽  
Author(s):  
J. Ahdidan ◽  
L. B. Hviid ◽  
M. M. Chakravarty ◽  
B. Ravnkilde ◽  
R. Rosenberg ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Brain Structure ◽  
Major Depressive ◽  
Hippocampus Volume ◽  
Mr Study
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