Recent cannabis use is associated with smaller hippocampus volume: High‐resolution segmentation of structural subfields in a large non‐clinical sample

2020 ◽  
Vol 26 (1) ◽  
Author(s):  
Max M. Owens ◽  
Lawrence H. Sweet ◽  
James MacKillop
Keyword(s):  
High Resolution ◽  
Clinical Sample ◽  
Cannabis Use ◽  
Hippocampus Volume

U-shaped curve of psychosis according to cannabis use: New evidence from a snowball sample

2016 ◽  
Vol 30 (12) ◽  
pp. 1331-1338 ◽  
Author(s):  
Antía Brañas ◽  
María L Barrigón ◽  
Nathalia Garrido-Torres ◽  
Salvador Perona-Garcelán ◽  
Juan F Rodriguez-Testal ◽  
...  
Keyword(s):  
Social Exclusion ◽  
Age Of Onset ◽  
Clinical Sample ◽  
Cannabis Use ◽  
Psychotic Experiences ◽  
Snowball Sampling ◽  
Negative Dimension ◽  
Alcohol And Other Drugs ◽  
New Evidence ◽  
The Relationship

Background: The aim of this study was to investigate the relationship between psychotic-like experiences (PLEs) assessed using the Community Assessment of Psychic Experience (CAPE) questionnaire and the pattern of cannabis use in a non-clinical sample collected by snowball sampling. Methods: Our sample was composed of 204 subjects, distributed into three groups by their cannabis use pattern: 68 were non-cannabis users, 40 were moderate cannabis users and 96 were daily cannabis users. We assessed the psychotic experiences in each group with the CAPE questionnaire; and then controlled for the effect of possible confounding factors like sex, age, social exclusion, age of onset of cannabis use, alcohol use and other drug use. Results: We found a significant quadratic association between the frequency of cannabis use and positive (β = −1.8; p = 0.004) and negative dimension scores (β = −1.2; p = 0.04). The first-rank and mania factors showed a significant quadratic association ( p < 0.05), while the voices factor showed a trend ( p = 0.07). Scores for the different groups tended to maintain a U-shape in their values for the different factors. When we adjusted for gender, age, social exclusion, age of onset of cannabis use, and use of alcohol and other drugs, only the first-rank experiences remained significant. Conclusions: We found there was a U-shaped curve in the association between cannabis use and the positive and negative dimensions of the CAPE score. We also found this association in mania and first-rank experiences.

Cannabis use and delinquent behaviors in a non-clinical sample of adolescents

2010 ◽  
Vol 35 (3) ◽  
pp. 263-265 ◽  
Author(s):  
Henri Chabrol ◽  
Rachel F. Rodgers ◽  
Gwendoline Sobolewski ◽  
Nikki van Leeuwen
Keyword(s):  
Clinical Sample ◽  
Cannabis Use ◽  
Delinquent Behaviors

scholarly journals T55. ATTITUDE AND PATTERNS OF CANNABIS USE IN A CLINICAL SAMPLE OF PATIENTS WITH SCHIZOPHRENIA

2019 ◽  
Vol 45 (Supplement_2) ◽  
pp. S224-S225
Author(s):  
Naista Zhand ◽  
David Attwood
Keyword(s):  
Clinical Sample ◽  
Cannabis Use

scholarly journals Interferon λ 3 and 4 Genotyping Using High-Resolution Melt Curve Analysis Suitable for Multiple Clinical Sample Types

2015 ◽  
Vol 17 (5) ◽  
pp. 583-589 ◽  
Author(s):  
François M.J. Lamoury ◽  
Sofia Bartlett ◽  
Brendan Jacka ◽  
Behzad Hajarizadeh ◽  
Jason Grebely ◽  
...  
Keyword(s):  
High Resolution ◽  
Clinical Sample ◽  
Curve Analysis ◽  
High Resolution Melt ◽  
Melt Curve Analysis ◽  
Interferon Λ

scholarly journals Cannabis use and neurocognitive functioning in a non-clinical sample of users

2014 ◽  
Vol 39 (5) ◽  
pp. 994-999 ◽  
Author(s):  
April D. Thames ◽  
Natalie Arbid ◽  
Philip Sayegh
Keyword(s):  
Clinical Sample ◽  
Cannabis Use ◽  
Neurocognitive Functioning

scholarly journals Cannabis Use, Schizotypy and Kamin Blocking Performance

2021 ◽  
Vol 12 ◽  
Author(s):  
Christopher Dawes ◽  
Andrea Bickerdike ◽  
Cian O'Neill ◽  
Sarah Carneiro Pereira ◽  
John L. Waddington ◽  
...  
Keyword(s):  
Associative Learning ◽  
Clinical Sample ◽  
Cannabis Use ◽  
First Episode ◽  
Cross Sectional ◽  
Schizotypal Personality ◽  
Increased Risk ◽  
History Of ◽  
Aberrant Salience ◽  
The Relationship

Cannabis use has been associated with increased risk for a first episode of psychosis and inappropriate assignment of salience to extraneous stimuli has been proposed as a mechanism underlying this association. Psychosis-prone (especially schizotypal) personality traits are associated with deficits in associative learning tasks that measure salience allocation. The aim of this study was to examine the relationship between history of cannabis use and Kamin blocking (KB), a form of selective associative learning, in a non-clinical sample. Additionally, KB was examined in relation to self-reported schizotypy and aberrant salience scale profiles. A cross-sectional study was conducted in 307 healthy participants with no previous psychiatric or neurological history. Participants were recruited and tested using the Testable Minds behavioural testing platform. KB was calculated using Oades' “mouse in the house task”, performance of which is disrupted in schizophrenia patients. Schizotypy was measured using the Schizotypal Personality Questionnaire (SPQ), and the Aberrant Salience Inventory (ASI) was used to assess self-reported unusual or inappropriate salience. The modified Cannabis Experience Questionnaire (CEQm) was used to collect detailed history of use of cannabis and other recreational drugs. Regression models and Bayesian t-tests or ANOVA (or non-parametric equivalents) examined differences in KB based on lifetime or current cannabis use (frequent use during previous year), as well as frequency of use among those who had previously used cannabis. Neither lifetime nor current cannabis use was associated with any significant change in total or trial-specific KB scores. Current cannabis use was associated with higher Disorganised SPQ dimension scores and higher total and sub-scale values for the ASI. A modest positive association was observed between total KB score and Disorganised SPQ dimension scores, but no relationships were found between KB and other SPQ measures. Higher scores on “Senses Sharpening” ASI sub-scale predicted decreased KB score only in participants who have not engaged in recent cannabis use. These results are discussed in the context of our understanding of the effects of long-term cannabis exposure on salience attribution, as well as inconsistencies in the literature with respect to both the relationship between KB and schizotypy and the measurement of KB associative learning phenomena.

scholarly journals The interaction between the ZNF804A gene and cannabis use on the risk of psychosis in a non-clinical sample

2019 ◽  
Vol 89 ◽  
pp. 174-180 ◽  
Author(s):  
Jordi Soler ◽  
Bárbara Arias ◽  
Jorge Moya ◽  
Manuel Ignacio Ibáñez ◽  
Generós Ortet ◽  
...  
Keyword(s):  
Clinical Sample ◽  
Cannabis Use

Measuring alcohol and cannabis use disorders in an adolescent clinical sample.

1993 ◽  
Vol 7 (3) ◽  
pp. 185-196 ◽  
Author(s):  
Ken C. Winters ◽  
Randy D. Stinchfield ◽  
Jayne Fulkerson ◽  
George A. Henly
Keyword(s):  
Clinical Sample ◽  
Cannabis Use ◽  
Cannabis Use Disorders

SU136INTERACTION BETWEEN ZNF804A GENE AND CANNABIS USE ON THE RISK FOR PSYCHOSIS IN A NON-CLINICAL SAMPLE

2019 ◽  
Vol 29 ◽  
pp. S1338-S1339
Author(s):  
Jordi Soler Garcia ◽  
Barbara Arias ◽  
Jorge Moya ◽  
Manuel Ignacio Ibañez ◽  
Generós Ortet ◽  
...  
Keyword(s):  
Clinical Sample ◽  
Cannabis Use
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