scholarly journals Influence of hormone replacement therapy on the level of alkaline phosphatase and acid phosphatase in serum and saliva among women with estrogen deficiency

2012 ◽  
Vol 6 ◽  
pp. 506-509
Author(s):  
Mansur Rahnama ◽  
Tomasz Jachewicz ◽  
Michał Łobacz ◽  
Wioletta Czajkowska ◽  
Marcin Stelmaszczyk
Keyword(s):  
Alkaline Phosphatase ◽  
Hormone Replacement Therapy ◽  
Acid Phosphatase ◽  
Replacement Therapy ◽  
Hormone Replacement ◽  
Estrogen Deficiency

Markers of bone remodeling in patients with surgical menopause undergoing hormone replacement therapy with Divigel

2021 ◽  
Vol 50 (3) ◽  
pp. 70-75
Author(s):  
S. V. Yureneva ◽  
V. P. Smetnik ◽  
N. V. Lyubimova ◽  
V. M. Abaev
Keyword(s):  
Alkaline Phosphatase ◽  
Hormone Replacement Therapy ◽  
Replacement Therapy ◽  
Bone Tissue ◽  
Bone Remodeling ◽  
Hormone Replacement ◽  
Hormonal Replacement Therapy ◽  
Mineral Density ◽  
Hormonal Replacement ◽  
Surgical Menopause

Twenty women with surgical menopause, 40-50 years of age, received hormonal replacement therapy with transdermic preparation Divigel during 24 months. On the background of therapy with Divigel we witnessed normalization of indeces of osteal remodelingconsiderable decrease pyridinoline and deoxypyridinoline, and elevation of alkaline phosphatase. Mineral density of bone tissue in the group of patients with surgical menopause waslowerin comparison with control (p0,01). Divigeltumedto exertprotective influence on the bone tissue inpatients with osteoporosis irrespective о f duration о f surgical menopause by the beginning of therapy.

scholarly journals Revisiting the Cutaneous Impact of Oral Hormone Replacement Therapy

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Gérald E. Piérard ◽  
Philippe Humbert ◽  
Enzo Berardesca ◽  
Ulysse Gaspard ◽  
Trinh Hermanns-Lê ◽  
...  
Keyword(s):  
Hormone Replacement Therapy ◽  
Hormone Therapy ◽  
Replacement Therapy ◽  
Aging Process ◽  
Hormone Replacement ◽  
Estrogen Therapy ◽  
Estrogen Deficiency ◽  
Hair Follicles ◽  
Menstrual Period ◽  
Transdermal Estrogen

Menopause is a key point moment in the specific aging process of women. It represents a universal evolution in life. Its initiation is defined by a 12-month amenorrhea following the ultimate menstrual period. It encompasses a series of different biologic and physiologic characteristics. This period of life appears to spot a decline in a series of skin functional performances initiating tissue atrophy, withering, and slackness. Any part of the skin is possibly altered, including the epidermis, dermis, hypodermis, and hair follicles. Hormone replacement therapy (oral and nonoral) and transdermal estrogen therapy represent possible specific managements for women engaged in the climacteric phase. All the current reports indicate that chronologic aging, climacteric estrogen deficiency, and adequate hormone therapy exert profound effects on various parts of the skin.

scholarly journals Possibilities of HRT in solving the problem of psychosocial adaptation of girls with primary estrogen deficiency

2003 ◽  
Vol 52 (3) ◽  
pp. 69-74
Author(s):  
Е. V. Uvarova ◽  
N. E. Kharlamenkova ◽  
N. А. Astakhova ◽  
I. P. Meshkova
Keyword(s):  
Hormone Replacement Therapy ◽  
Replacement Therapy ◽  
Gonadal Dysgenesis ◽  
Hormone Replacement ◽  
Psychosocial Adaptation ◽  
Estrogen Deficiency ◽  
Adaptive Responses ◽  
Sex Reversion ◽  
Passport Data ◽  
First Time

This study presents the results of testing the hypothesis that girls during the period of normally proceeding puberty experience much more emotional discomfort, difficulties in communication and self-acceptance due to more pronounced hormonal and bodily changes than normally developing boys. Along with this, for the first time, results are presented that indicate some similarity of adaptive responses in boys with normal puberty and in girls with primary estrogen deficiency on the background of hormone replacement therapy (HRT). The development of girls with 450-gonadal dysgenesis (with Turner syndrome) on the background of HRT is considered as adaptive to the tasks of age, less than their passport data. Girls with XY-sex reversion with gonadal dysgenesis are assessed as sufficiently adapted due to certain personal and age characteristics.

ARTIFICIAL STIMULATORY AND HORMONAL REQUIREMENTS OF DECIDUAL ALKALINE PHOSPHATASE IN THE PSEUDOPREGNANT RAT

1969 ◽  
Vol 61 (1) ◽  
pp. 164-172 ◽  
Author(s):  
J. P. Manning ◽  
S. G. Carter ◽  
M. C. Butler
Keyword(s):  
Alkaline Phosphatase ◽  
Enzyme Activity ◽  
Hormone Replacement Therapy ◽  
Replacement Therapy ◽  
Hormone Replacement ◽  
Similar Response ◽  
Fallopian Tubes ◽  
Pregnant Rats ◽  
Implantation Sites ◽  
Alkaline Phosphatase Reaction

ABSTRACT The influences of uterine traumatization, ovariectomy and hormone replacement therapy on decidual alkaline phosphatase were studied in pseudopregnant rats. The enzyme was also assayed in implantation sites of pregnant rats with unilateral section and ligation of the Fallopian tubes. In all pseudopregnant animals with traumatized uteri, intact or castrate receiving progesterone replacement, the enzyme activity was 12 times more active on day 8 of pseudopregnancy than the contralateral non-traumatized horn. The alkaline phosphatase reaction of day 8 pregnant rats demonstrated a similar response at the implantation site. No increased enzyme was elicited by pseudopregnant rats treated with 17β-oestradiol and/or progesterone or animals ovariectomized and traumatized on day 4 and given only oestrogen. Additionally, the changes in alkaline phosphatase from day 5 to 10 in the intact and hormone-treated, ovariectomized pseudopregnant rats with traumatized uteri were similar to those demonstrated by the intact pregnant animals, i. e., an increased reaction from day 5 to 8 and decreased activity from day 8 to 10. The data support the view that the rise in decidual alkaline phosphatase in pregnant or traumatized pseudopregnant animals is dependent on the combined effect of uterine irritation and a progesterone-conditioned endometrium.

scholarly journals The effect of hormone replacement therapy on the expression of the alkaline phosphatase gene (ALPL) within the mucosal epithelium of the cheek and in peripheral blood lymphocytes

2014 ◽  
Vol 27 (2) ◽  
pp. 92-96 ◽  
Author(s):  
Mansur Rahnama ◽  
Michal Lobacz ◽  
Anna Szyszkowska ◽  
Grzegorz Trybek ◽  
Maryla Kozicka-Czupkallo
Keyword(s):  
Alkaline Phosphatase ◽  
Hormone Replacement Therapy ◽  
Bone Formation ◽  
Replacement Therapy ◽  
Peripheral Blood ◽  
Bone Mineralization ◽  
Hormone Replacement ◽  
Peripheral Blood Lymphocytes ◽  
Mucosal Epithelium ◽  
Osteoblast Activity

Abstract In adult life, proper bone metabolism requires efficient regulation of bone formation and resorption processes. Bone turnover markers allow for assessing the rate of bone formation and resorption processes. In menopausal period, female patients experience gradual reduction in blood estradiol levels. The deficit of estrogens leads to enhanced osteoclastogenesis and bone resorption. Alkaline phosphatase (ALP) is a membranebound enzyme that stimulates the osteoblast activity and bone mineralization. It is synthesized by osteoblasts and incorporated into the newly formed bone tissue. The produced enzyme stimulates the osteoblast activity and bone mineralization. The goal of this study is to determine the effect of hormone replacement therapy in postmenopausal women on the expression of alkaline phosphatase gene (ALPL) within the mucosal epithelium of the cheek and in peripheral blood lymphocytes. The studies show that hormone replacement therapy has no significant effect on the increase in ALPL expression within the mucosal epithelium of the cheek. Only in women having undergone ovarectomy (OV), the epithelial ALPL expression level was higher than in the remaining groups.

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