scholarly journals Comparison of tyrosinase antibody, tyrosinase-related protein-1 and -2 antibodies, melanin-concentrating hormone receptor antibody levels with autologous serum skin test and autologous plasma skin test results in patients with vitiligo

2020 ◽  
Author(s):  
Abdullah Unal ◽  
Hatice Uce Ozkol ◽  
Yasemin Bayram ◽  
Necmettin Akdeniz
Keyword(s):  
Skin Test ◽  
Hormone Receptor ◽  
Autologous Serum ◽  
Test Results ◽  
Related Protein ◽  
Autologous Plasma ◽  
Autologous Serum Skin Test ◽  
Melanin Concentrating Hormone ◽  
Antibody Levels ◽  
Tyrosinase Related Protein

scholarly journals Autologous Serum Skin Test as a Diagnostic Aid in Chronic Idiopathic Urticaria

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Hayder R. Al-Hamamy ◽  
Ammar F. Hameed ◽  
Asaad S. Abdulhadi
Keyword(s):  
Skin Test ◽  
Clinical Features ◽  
Chronic Idiopathic Urticaria ◽  
Autologous Serum ◽  
Test Results ◽  
Autologous Serum Skin Test ◽  
Autoimmune Urticaria ◽  
Number Of Patients ◽  
Significant Difference ◽  
The Face

Background. Chronic urticaria is defined as urticaria persisting daily for more than six weeks. A significant number of patients had autoimmune basis where autologous serum skin test is widely used for detection of chronic autoimmune urticaria. Objectives. To estimate the frequency of autoimmune urticarial in Iraqi patients utilizing the autologous serum skin test and to evaluate its results with the variable clinical features of chronic idiopathic urticaria. Methods. In this prospective study, 54 patients with chronic idiopathic urticaria were investigated with autologous serum skin test where its results were examined with the different clinical parameters of chronic autoimmune urticaria. Results. Twenty two patients (40.7%) out of 54 patients with chronic idiopathic urticarial had positive autologous serum skin test. Statistical analysis of the clinical variables did not show a significant difference between patients with positive and negative autologous serum skin test except for the distribution of wheals on the face and extremities which was significantly associated with positive autologous serum skin test results (P value 0.004). Conclusion. Autologous serum skin test is a simple, office-based test for detecting chronic autoimmune urticaria patients who have no distinctive clinical features differentiating them from chronic idiopathic urticaria patients.

Influence of narrowband UVB irradiation of serum on autologous serum skin test results

2013 ◽  
Vol 52 (9) ◽  
pp. 1088-1091 ◽  
Author(s):  
Nida Kaar ◽  
Levent Taşli ◽  
Berna Şanlı ◽  
Mustafa Topsakal
Keyword(s):  
Skin Test ◽  
Autologous Serum ◽  
Test Results ◽  
Uvb Irradiation ◽  
Autologous Serum Skin Test ◽  
Narrowband Uvb

scholarly journals Association between chronic spontaneous urticaria and thyroid autoimmunity: a case control study from a tertiary care centre

2017 ◽  
Vol 3 (1) ◽  
pp. 64 ◽  
Author(s):  
Olasseri K. Reena Mariyath ◽  
Manikoth P. Binitha ◽  
Vadakke P. Anilakumari ◽  
George Biju ◽  
Pappinisseri K. Nikhila ◽  
...  
Keyword(s):  
Skin Test ◽  
Thyroid Function ◽  
Antibody Level ◽  
Thyroid Autoimmunity ◽  
Chronic Spontaneous Urticaria ◽  
Autologous Serum ◽  
Thyroid Peroxidase ◽  
Thyroid Function Tests ◽  
Autologous Serum Skin Test ◽  
Antibody Levels

<p class="abstract"><strong>Background:</strong> The exact etiology of chronic spontaneous urticaria is unknown in the majority of patients. A subset of chronic spontaneous urticaria can be autoimmune and may be associated with thyroid autoimmunity<span lang="EN-IN">.</span></p><p class="abstract"><strong>Methods:</strong> Serum anti thyroid peroxidase (anti-TPO) antibody level and thyroid function tests (TFT) including triiodothyronine (T3), thyroxine (T4) and thyroid stimulating hormone (TSH) levels were estimated in 100patients with chronic spontaneous urticaria and 50 controls. Autologous serum skin test (ASST) was done in 84 chronic urticaria patients and 21 patients with high anti-TPO antibody.<strong></strong></p><p class="abstract"><strong>Results:</strong> High anti-TPO antibodies and abnormal thyroid function were seen in 24 (24%) patients each. High anti-TPO antibody levels were seen in nine (18%) and abnormal TFT in 11 (22%) controls. Abnormal TSH was seen in 22 patients (22%) and 6 (12%) controls. Autologous serum skin test was positive in 53 patients with chronic spontaneous urticaria. It was positive in 16 and negative in five out of 21 patients with high anti-TPO antibody levels<span lang="EN-IN">. </span></p><p class="abstract"><strong>Conclusions:</strong> Though there was a slight increase in abnormal anti-TPO antibody level and thyroid dysfunction in patients with chronic spontaneous urticaria compared to controls, it was not statistically significant<span lang="EN-IN">.</span></p>

scholarly journals Autologous Serum Skin Test versus Autologous Plasma Skin Test in Patients with Chronic Spontaneous Urticaria

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Aysegul Alpay ◽  
Nilgün Solak Tekin ◽  
Ishak Özel Tekin ◽  
H. Cevdet Altinyazar ◽  
Rafet Koca ◽  
...  
Keyword(s):  
Skin Test ◽  
Chronic Spontaneous Urticaria ◽  
Autologous Serum ◽  
Thyroid Autoantibodies ◽  
Thyroid Function Tests ◽  
Control Groups ◽  
Autologous Plasma ◽  
Autologous Serum Skin Test ◽  
Autoimmune Urticaria ◽  
And Control

Previous studies indicate that 25–45% of chronic urticaria patients have an autoimmune etiology. Autologous serum skin test (ASST) and autologous plasma skin test (APST) are simple tests for diagnosing chronic autoimmune urticaria (CAU). However, there are still some questions about the specificity of these tests. This study consisted of 50 patients with chronic spontaneous urticaria (CSU) and 50 sex- and age-matched healthy individuals aged 18 years, and older. A total of 31 (62%) patients and 5 (10%) control patients had positive ASST; 21 (42%) patients and 3 (6%) control patients had positive APST. Statistically significant differences were noted in ASST and APST positivity between the patient and control groups (ASSTP<0.001; APSTP<0.001). Thirteen (26%) patients and 5 (10%) control patients had antithyroglobulin antibodies or antithyroid peroxidase antibody positivity. No statistically significant differences were noted in thyroid autoantibodies between the patient and control groups (anti-TGP=0.317; anti-TPOP=0.269). We consider that the ASST and APST can both be used asin vivotests for the assessment of autoimmunity in the etiology of CSU and that thyroid autoantibodies should be checked even when thyroid function tests reveal normal results in patients with CSU.

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