scholarly journals Does Inhibition of Arginase and Advanced Glycation End Products Provide a Protection Against Experimentally Induced Diabetic Nephropathy

2015 ◽  
pp. 242-251
Author(s):  
Noha I. Hussien
Keyword(s):  
Diabetic Nephropathy ◽  
Advanced Glycation End Products ◽  
Advanced Glycation ◽  
Glycation End Products ◽  
End Products ◽  
Experimentally Induced

Effect of pyridoxamine (K-163), an inhibitor of advanced glycation end products, on type 2 diabetic nephropathy in KK-Ay/Ta mice

Metabolism ◽  
2007 ◽  
Vol 56 (2) ◽  
pp. 160-167 ◽  
Author(s):  
Mitsuo Tanimoto ◽  
Tomohito Gohda ◽  
Shigeru Kaneko ◽  
Shinji Hagiwara ◽  
Maki Murakoshi ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Advanced Glycation End Products ◽  
Advanced Glycation ◽  
Glycation End Products ◽  
End Products ◽  
Type 2 Diabetic

scholarly journals Advanced glycation end-products in diabetic nephropathy

1996 ◽  
Vol 11 (supp5) ◽  
pp. 91-94 ◽  
Author(s):  
S. Sugiyama ◽  
T. Miyata ◽  
K. Horie ◽  
Y. Iida ◽  
M. Tsuyuki ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Advanced Glycation End Products ◽  
Advanced Glycation ◽  
Glycation End Products ◽  
End Products

AGE, RAGE and Diabetic Nephropathy

2010 ◽  
Vol 8 (2) ◽  
pp. 84
Author(s):  
MaÏté Daroux ◽  
Nicolas Grossin ◽  
Eric Boulanger ◽  
◽  
◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Diabetic Nephropathy ◽  
Kidney Disease ◽  
Advanced Glycation End Products ◽  
Specific Treatment ◽  
Therapeutic Approaches ◽  
Advanced Glycation ◽  
Glycation End Products ◽  
End Products ◽  
Immunohistochemical Studies

Diabetes is a disease that is present worldwide and which is associated with a large number of potential complications including chronic kidney disease (CKD). Several factors have been implicated in the development of the latter, including advanced glycation end-products (AGEs), which are formed from the interaction between sugar and proteins. AGE toxicity may be triggered via different mechanisms, especially by receptor binding. Immunohistochemical studies have demonstrated the presence of AGEs in all renal structures (vessels, glomeruli, tubules and the interstitium). They appear to be involved in the exacerbation of renal injury observed during diabetic nephropathy. At present, no specific treatment is yet available, although several therapeutic approaches are under development.

scholarly journals Roles of advanced glycation end-products in the progression of diabetic nephropathy

1996 ◽  
Vol 11 (supp5) ◽  
pp. 76-80 ◽  
Author(s):  
H. Makino ◽  
K. Shikata ◽  
M. Kushiro ◽  
K. Hironaka ◽  
Y. Yamasaki ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Advanced Glycation End Products ◽  
Advanced Glycation ◽  
Glycation End Products ◽  
End Products

Ellagic acid inhibits non-enzymatic glycation and prevents proteinuria in diabetic rats

2016 ◽  
Vol 7 (3) ◽  
pp. 1574-1583 ◽  
Author(s):  
G. Raghu ◽  
Sneha Jakhotia ◽  
P. Yadagiri Reddy ◽  
P. Anil Kumar ◽  
G. Bhanuprakash Reddy
Keyword(s):  
Diabetic Nephropathy ◽  
Characteristic Feature ◽  
Advanced Glycation End Products ◽  
Ellagic Acid ◽  
Diabetic Rats ◽  
Advanced Glycation ◽  
Glycation End Products ◽  
End Products

The formation of advanced glycation end products (AGEs) is a characteristic feature of diabetic tissues and accumulation of AGEs been implicated in the pathogenesis of diabetic nephropathy (DN). Ellagic acid prevented the accumulation of AGEs and in turn ameliorated proteinurea in diabetic rats.

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