Ellagic acid inhibits non-enzymatic glycation and prevents proteinuria in diabetic rats

2016 ◽  
Vol 7 (3) ◽  
pp. 1574-1583 ◽  
Author(s):  
G. Raghu ◽  
Sneha Jakhotia ◽  
P. Yadagiri Reddy ◽  
P. Anil Kumar ◽  
G. Bhanuprakash Reddy

The formation of advanced glycation end products (AGEs) is a characteristic feature of diabetic tissues and accumulation of AGEs been implicated in the pathogenesis of diabetic nephropathy (DN). Ellagic acid prevented the accumulation of AGEs and in turn ameliorated proteinurea in diabetic rats.

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