scholarly journals American Bullfrogs as Invasive Species: A Review of the Introduction, Subsequent Problems, Management Options, and Future Directions

2010 ◽  
Vol 24 ◽  
Author(s):  
Nathan , P. Snow ◽  
Gary Witmer
Keyword(s):  
Invasive Species ◽  
Management Options ◽  
Future Directions

scholarly journals Enabling decisions that make a difference: guidance for improving access to and analysis of invasive species information

2019 ◽  
Vol 22 (1) ◽  
pp. 37-45 ◽  
Author(s):  
Rebekah D. Wallace ◽  
Charles T. Bargeron ◽  
Jamie K. Reaser
Keyword(s):  
Invasive Species ◽  
Information Systems ◽  
Information Sharing ◽  
Data Sharing ◽  
Relevant Information ◽  
Global Biodiversity Information Facility ◽  
Management Options ◽  
The North ◽  
Socio Economic Impact ◽  
Taxonomic Groups

AbstractThe issue of how to detect and rapidly respond to invasive species before it is economically infeasible to control them is one of urgency and importance at international, national, and subnational scales. Barriers to sharing invasive species data—whether in the form of policy, culture, technology, or operational logistics—need to be addressed and overcome at all levels. We propose guiding principles for following standards, formats, and protocols to improve information sharing among US invasive species information systems and conclude that existing invasive species information standards are adequate for the facilitation of data sharing among all sectors. Rather than creating a single information-sharing system, there is a need to promote interfaces among existing information systems that will enable them to become inter-operable, to foster simultaneous access, and to deliver any and all relevant information to a particular user or application in a seamless fashion. The actions we propose include implementing a national campaign to mobilize invasive species occurrence data into publicly available information systems; maintaining a current list of invasive species data integrators/clearinghouses; establishing an agreement for sharing data among the primary US invasive species information systems; enhancing the Integrated Taxonomic Information System to fully cover taxonomic groups not yet complete; further developing and hosting data standards for critical aspects of invasive species biology; supporting and maintaining the North American Invasive Species Management Association’s mapping standards; identifying standard metrics for capturing the environmental and socio-economic impact of invasive species, including impacts and management options; continuing to support US engagement in international invasive species data sharing platforms; and continuing US membership in the Global Biodiversity Information Facility.

scholarly journals Malignant Pleural Effusions: Management Options

2018 ◽  
Vol 39 (06) ◽  
pp. 704-712 ◽  
Author(s):  
Jose Porcel ◽  
Najib Rahman ◽  
David McCracken
Keyword(s):  
Malignant Pleural Effusion ◽  
Conventional Treatment ◽  
Fibrinolytic Therapy ◽  
Patient Benefit ◽  
Management Options ◽  
Future Directions ◽  
Population Demographics ◽  
Health Care Burden ◽  
Significant Health

AbstractMalignant pleural effusion (MPE) represents advanced metastatic malignancy and is associated with poor median survival. Incidence remains high and continues to rise, in part due to changing population demographics. This therefore represents a significant health care burden. Management is predominantly palliative in nature and multiple interventions are available within conventional treatment paradigms, all of which are proven to result in statistically significant patient benefit. This article further explores the methods available in the management of MPE along with the pitfalls, complications, and alternatives. Recent advances within the field are discussed with an exploration of likely future directions, including the role of ultrasound as a prospective predictor and the role of intrapleural fibrinolytic therapy.

scholarly journals The Protein Landscape of Mucinous Ovarian Cancer: Towards a Theranostic

Cancers ◽  
2021 ◽  
Vol 13 (22) ◽  
pp. 5596
Author(s):  
Arkan Youssef ◽  
Mohammad B. Haskali ◽  
Kylie L. Gorringe
Keyword(s):  
Ovarian Cancer ◽  
Personalised Medicine ◽  
Membrane Expression ◽  
Management Options ◽  
Current Management ◽  
Future Directions ◽  
Disease Outcomes ◽  
Theranostic Agents ◽  
Selection Of ◽  
Target Effects

MOC is a rare histotype of epithelial ovarian cancer, and current management options are inadequate for the treatment of late stage or recurrent disease. A shift towards personalised medicines in ovarian cancer is being observed, with trials targeting specific molecular pathways, however, MOC lags due to its rarity. Theranostics is a rapidly evolving category of personalised medicine, encompassing both a diagnostic and therapeutic approach by recognising targets that are expressed highly in tumour tissue in order to deliver a therapeutic payload. The present review evaluates the protein landscape of MOC in recent immunohistochemical- and proteomic-based research, aiming to identify potential candidates for theranostic application. Fourteen proteins were selected based on cell membrane localisation: HER2, EGFR, FOLR1, RAC1, GPR158, CEACAM6, MUC16, PD-L1, NHE1, CEACAM5, MUC1, ACE2, GP2, and PTPRH. Optimal proteins to target using theranostic agents must exhibit high membrane expression on cancerous tissue with low expression on healthy tissue to afford improved disease outcomes with minimal off-target effects and toxicities. We provide guidelines to consider in the selection of a theranostic target for MOC and suggest future directions in evaluating the results of this review.

scholarly journals Pulmonary Arterial Hypertension and Therapeutic Interventions

2019 ◽  
Vol 28 (02) ◽  
pp. 080-092 ◽  
Author(s):  
Nader B. Ishak Gabra ◽  
Omar Mahmoud ◽  
Oki Ishikawa ◽  
Varun Shah ◽  
Erica Altshul ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Review Article ◽  
Therapeutic Interventions ◽  
Management Options ◽  
Future Directions ◽  
Uncommon Disease ◽  
Disease Entities ◽  
Pulmonary Arterial

AbstractPulmonary hypertension is an uncommon disease that carries a significant morbidity and mortality. Pulmonary arterial hypertension is a subtype of pulmonary hypertension that describes a group of disease entities that lead to an elevation in precapillary pulmonary artery pressure. Despite advances in the diagnosis and treatment of pulmonary arterial hypertension, it remains a difficult disease to recognize and manage. In this review article, we will discuss the definition and diagnosis of pulmonary arterial hypertension. Additionally, we will discuss the ever-expanding management options, their mechanisms and strategies, including combination therapy and the most recent advances and future directions.

scholarly journals Management of Intrahepatic Cholangiocarcinoma

2021 ◽  
Vol 10 (11) ◽  
pp. 2368
Author(s):  
Sudha Kodali ◽  
Akshay Shetty ◽  
Soumya Shekhar ◽  
David W. Victor ◽  
Rafik M. Ghobrial
Keyword(s):  
Intrahepatic Cholangiocarcinoma ◽  
Clinical Presentation ◽  
Progression Free Survival ◽  
Biliary Tree ◽  
Disease Course ◽  
External Radiation ◽  
Management Options ◽  
Future Directions ◽  
Free Survival ◽  
Disease Free

Cholangiocarcinoma is a tumor that arises as a result of differentiation of the cholangiocytes and can develop from anywhere in the biliary tree. Subtypes of cholangiocarcinoma are differentiated based on their location in the biliary tree. If diagnosed early these can be resected, but most cases of intrahepatic cholangiocarcinoma present late in the disease course where surgical resection is not an option. In these patients who are poor candidates for resection, a combination of chemotherapy, locoregional therapies like ablation, transarterial chemo and radioembolization, and in very advanced and metastatic disease, external radiation are the available options. These modalities can improve overall disease-free and progression-free survival chances. In this review, we will discuss the risk factors and clinical presentation of intrahepatic cholangiocarcinoma, diagnosis, available therapeutic options, and future directions for management options.

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