scholarly journals Immediate resolution of severe bullous chronic regional pain syndrome with onset of spinal paralysis

2015 ◽  
Vol 21 (9) ◽  
Author(s):  
Lissy Hu ◽  
Alice J Watson ◽  
Scott R Granter ◽  
Adam D Lipworth
Keyword(s):  
Pain Syndrome ◽  
Chronic Regional Pain Syndrome ◽  
Spinal Paralysis

scholarly journals A Long-Term Observation on the Possible Adverse Effects in Japanese Adolescent Girls after Human Papillomavirus Vaccination

Vaccines ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 856
Author(s):  
Akiyo Hineno ◽  
Shu-Ihi Ikeda
Keyword(s):  
Human Papillomavirus ◽  
Adverse Effects ◽  
Orthostatic Intolerance ◽  
Hpv Vaccination ◽  
Pain Syndrome ◽  
Causal Link ◽  
Human Papillomavirus Vaccination ◽  
Chronic Regional Pain Syndrome ◽  
Laboratory Test Results ◽  
Long Term Observation

In Japan, a significant number of adolescent females noted unusual symptoms after receiving the human papillomavirus (HPV) vaccination, of which the vast majority of them were initially diagnosed with psychiatric illnesses because of the absence of pathologic radiological images and specific abnormalities in laboratory test results. Later these symptoms were thought to be adverse effects of HPV vaccination. However, a causal link between HPV vaccination and the development of these symptoms has not been demonstrated. Between June 2013 and March 2021, we examined 200 patients who noted various symptoms after HPV vaccination. In total, 87 were diagnosed with HPV vaccination-related symptoms based on our proposed diagnostic criteria. The clinical histories of these 87 patients were analyzed. The age at initial vaccination ranged from 11 to 19 years old (mean ± SD: 13.5 ± 1.5 years old), and the age at the first appearance of symptoms ranged from 12 to 20 years old (mean ± SD: 14.3 ± 1.6 years old). The patients received an initial HPV vaccine injection between May 2010 and May 2013, but the first affected patient developed symptoms in October 2010, and the last affected developed symptoms in October 2015. A cluster of patients with a post-HPV vaccination disorder has not appeared in Japan during the last five years. Our study shows that, in Japan, the period of HPV vaccination considerably overlapped with that of a unique post-HPV vaccination disorder development. This disorder appears as a combination of orthostatic intolerance, chronic regional pain syndrome, and cognitive dysfunction, but its exact pathogenesis remains unclear.

scholarly journals Disease-related knowledge of patients with chronic regional pain syndrome

2010 ◽  
Vol 42 (5) ◽  
pp. 458-462 ◽  
Author(s):  
F Brunner ◽  
A Gymesi ◽  
R Kissling ◽  
LM Bachmann
Keyword(s):  
Pain Syndrome ◽  
Chronic Regional Pain Syndrome

Functional dystonia in the foot and ankle

2021 ◽  
Vol 103-B (6) ◽  
pp. 1127-1132
Author(s):  
Julia Gray ◽  
Matthew Welck ◽  
Nicholas P. Cullen ◽  
Dishan Singh
Keyword(s):  
Age Of Onset ◽  
Pain Syndrome ◽  
Rapid Onset ◽  
Response To Treatment ◽  
Foot And Ankle ◽  
Mean Delay ◽  
Chronic Regional Pain Syndrome ◽  
Injury Event ◽  
The Mean ◽  
A Minor

Aims To assess the characteristic clinical features, management, and outcome of patients who present to orthopaedic surgeons with functional dystonia affecting the foot and ankle. Methods We carried out a retrospective search of our records from 2000 to 2019 of patients seen in our adult tertiary referral foot and ankle unit with a diagnosis of functional dystonia. Results A total of 29 patients were seen. A majority were female (n = 25) and the mean age of onset of symptoms was 35.3 years (13 to 71). The mean delay between onset and diagnosis was 7.1 years (0.5 to 25.0). Onset was acute in 25 patients and insidious in four. Of the 29 patients, 26 had a fixed dystonia and three had a spasmodic dystonia. Pain was a major symptom in all patients, with a coexisting diagnosis of chronic regional pain syndrome (CRPS) made in nine patients. Of 20 patients treated with Botox, only one had a good response. None of the 12 patients who underwent a surgical intervention at our unit or elsewhere reported a subjective overall improvement. After a mean follow-up of 3.2 years (1 to 12), four patients had improved, 17 had remained the same, and eight reported a deterioration in their condition. Conclusion Patients with functional dystonia typically presented with a rapid onset of fixed deformity after a minor injury/event and pain out of proportion to the deformity. Referral to a neurologist to rule out neurological pathology is advocated, and further management should be carried out in a movement disorder clinic. Response to treatment (including Botulinum toxin (Botox) injections) is generally poor. Surgery in this group of patients is not recommended and may worsen the condition. The overall prognosis remains poor. Cite this article: Bone Joint J 2021;103-B(6):1127–1132.

scholarly journals Severe Pediatric Wrist Joint Sequelae following Blunt Trauma in the Presence of Chronic Regional Pain Syndrome

2019 ◽  
Vol 12 (03) ◽  
pp. 212-214
Author(s):  
Mohammad M. Abualruz ◽  
Sebastian Farr
Keyword(s):  
Blunt Trauma ◽  
Wrist Joint ◽  
Pain Syndrome ◽  
Cartilage Degeneration ◽  
Causative Factor ◽  
Therapeutic Interventions ◽  
Wrist Arthroscopy ◽  
Symptom Improvement ◽  
Type I ◽  
Chronic Regional Pain Syndrome

Abstract Introduction The pediatric chronic regional pain syndrome (CRPS) type I is a recognized syndrome that follows a preliminary event (e.g., trauma, fracture) with amplified spontaneous or stimuli-induced extremity pain that differs from its adult form with rather favorable outcomes. Conservative treatment is usually indicated for CRPS treatment. Case Description We present a unique case of an adolescent girl who revealed severe wrist joint sequelae following a blunt trauma, complicated by a challenging CRPS resistant to treatment. Diagnostic wrist arthroscopy eventually revealed a massive cartilage degeneration and scapholunate tear as underlying causes for the pain and CRPS. It was decided to proceed with radioscapholunate wrist fusion, which promptly led to pain relief and disappearance of the CRPS. Conclusion The relevance of this report is therefore to emphasize the possibility, against earlier thoughts, that well-indicated surgeries in pediatric CRPS patients may lead to prompt symptom improvement and may not be uniformly predicted to fail. With the clinical probability of a presence of an uncontrolled, symptomatic causative factor such as cartilage degeneration and chondrolysis, further early diagnostic and therapeutic interventions may be indicated to control the disease.

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