scholarly journals Association Between Visceral Hypersensitivity in Irritable Bowel Syndrome, Intestinal Microbiota, and Mast Cells: How to Detect Mast Cells Using Confocal Microscopy

2021 ◽  
Vol 27 (4) ◽  
pp. 657-659
Author(s):  
Kang Nyeong Lee ◽  
Jiwon Lee ◽  
Juil Hwang ◽  
Chungha Lee ◽  
Ji Sook Kim ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Mast Cells ◽  
Confocal Microscopy ◽  
Intestinal Microbiota ◽  
Visceral Hypersensitivity ◽  
Irritable Bowel

scholarly journals Prostaglandin E2, Produced by Mast Cells in Colon Tissues From Patients With Irritable Bowel Syndrome, Contributes to Visceral Hypersensitivity in Mice

2020 ◽  
Vol 158 (8) ◽  
pp. 2195-2207.e6 ◽  
Author(s):  
Gintautas Grabauskas ◽  
Xiaoyin Wu ◽  
Jun Gao ◽  
Ji-Yao Li ◽  
Danielle Kim Turgeon ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Mast Cells ◽  
Prostaglandin E2 ◽  
Visceral Hypersensitivity ◽  
Irritable Bowel

680 Associations of Abdominal Pain and Visceral Hypersensitivity With Intestinal Microbiota in Patients With Irritable Bowel Syndrome

2015 ◽  
Vol 148 (4) ◽  
pp. S-131-S-132
Author(s):  
Yehuda Ringel ◽  
Jarkko Salojarvi ◽  
Tamar Ringel-Kulka ◽  
Ian M. Carroll ◽  
Willem M. de Vos
Keyword(s):  
Irritable Bowel Syndrome ◽  
Abdominal Pain ◽  
Intestinal Microbiota ◽  
Visceral Hypersensitivity ◽  
Irritable Bowel

scholarly journals Role of mucosal mast cells in visceral hypersensitivity in a rat model of irritable bowel syndrome

2004 ◽  
Vol 5 (4) ◽  
pp. 319 ◽  
Author(s):  
Jun Ho La ◽  
Tae Wan Kim ◽  
Tae Sik Sung ◽  
Hyun Ju Kim ◽  
Jeom Yong Kim ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Mast Cells ◽  
Rat Model ◽  
Visceral Hypersensitivity ◽  
Mucosal Mast Cells ◽  
Irritable Bowel

scholarly journals Altered Intestinal Microbiota with Increased Abundance of Prevotella Is Associated with High Risk of Diarrhea-Predominant Irritable Bowel Syndrome

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Tingting Su ◽  
Rongbei Liu ◽  
Allen Lee ◽  
Yanqin Long ◽  
Lijun Du ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
High Risk ◽  
Gut Microbiota ◽  
Intestinal Microbiota ◽  
Visceral Hypersensitivity ◽  
Etiologic Factor ◽  
Healthy Controls ◽  
Microbial Composition ◽  
Fecal Samples ◽  
Irritable Bowel

Alterations in gut microbiota are postulated to be an etiologic factor in the pathogenesis of irritable bowel syndrome (IBS). To determine whether IBS patients in China exhibited differences in their gut microbial composition, fecal samples were collected from diarrhea-predominant IBS (IBS-D) and healthy controls and evaluated by 16S ribosomal RNA gene sequence and quantitative real-time PCR. A mouse model of postinfectious IBS (PI-IBS) was established to determine whether the altered gut microbiota was associated with increased visceral hypersensitivity. The results indicated that there were significant differences in the bacterial community profiles between IBS-D patients and healthy controls. Prevotella was more abundant in fecal samples from IBS-D patients compared with healthy controls (p<0.05). Meanwhile, there were significant reductions in the quantity of Bacteroides, Bifidobacteria, and Lactobacillus in IBS-D patients compared with healthy controls (p<0.05). Animal models similarly showed an increased abundance of Prevotella in fecal samples compared with control mice (p<0.05). Finally, after the PI-IBS mice were cohoused with control mice, both the relative abundance of Prevotella and visceral hypersensitivity of PI-IBS mice were decreased. In conclusion, the altered intestinal microbiota is associated with increased visceral hypersensitivity and enterotype enriched with Prevotella may be positively associated with high risk of IBS-D.

The intestinal microbiota changes paradigms in irritable bowel syndrome

Infectio ro ◽  
2017 ◽  
Vol 2 (50) ◽  
Author(s):  
Gabriela-Loredana Popa ◽  
Silvana-Adelina Gheorghe ◽  
Mădălina Preda
Keyword(s):  
Irritable Bowel Syndrome ◽  
Intestinal Microbiota ◽  
Irritable Bowel

Modern possibilities for correction of visceral hypersensitivity in patients with irritable bowel syndrome

2020 ◽  
Vol 0 (2) ◽  
pp. 37-44
Author(s):  
І. М. Skrypnyk ◽  
I. H. Kryvoruchko ◽  
O. F. Gopko ◽  
N. P. Prykhodko
Keyword(s):  
Irritable Bowel Syndrome ◽  
Visceral Hypersensitivity ◽  
Irritable Bowel
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