INFECCIÓN POR UNCINARIAS EN UN LACTANTE MENOR: REPORTE DE CASO

2020 ◽  
Vol 31 (1) ◽  
Author(s):  
José Luis Ayala ◽  
Lorena Romero ◽  
Gabriela Cuvi

Hookworms are endemic nematodes from tropical regions. Infection is more common in preschool and school children, but it is less frequent in infants under 6 months, because of the transmission mechanism that implies contact between contaminated soil and skin. The clinical disease is characterized by manifestations related to iron-deficiency anemia, secondary to a chronic digestive blood loss. An unusual way of presentation is the massive digestive bleeding that causes severe anemia. Case report: A four month shuar girl with no significant medical history, referred from General Puyo hospital, presented upper digestive bleeding of 3 months duration. At month of age, the girl presented self-limited melenas and skin pallor that worsen two weeks before the admission. The girl was hypo active, with a pale complexion, and had edema of feet. Her blood count showed hemoglobin 2.8 g/dl, hematocrit 9%, mean corpuscular volume 73 fl, red cell distribution width 18%, reticulocyte count 1%, eosinophils 4%. Coprological analysis reported tarry stools, positive fecal occult blood test, and hookworm eggs determined by Kato – Katz as a moderate infection. It was diagnosed iron-deficiency anemia secondary to an upper digestive bleeding caused by hookworms. The infection was treated with a single oral dose of albendazole 400mg plus blood transfusion. After 5 days of treatment, hemoglobin increased and edema was reduced. Melenas disappeared completely. Finally the discharge was indicated for outdoor control. Conclusion: Hookworm infestation is an endemic disease whose presence and impact in infants has been underestimated because it is not necessary as a cause of digestive bleeding. This disease should be considered in contexts of endemic areas in children who meet a clinical profile similar to that described.

2020 ◽  
Vol 148 (1-2) ◽  
pp. 31-36
Author(s):  
Dusan Popovic ◽  
Simon Zec ◽  
Ivan Rankovic ◽  
Tijana Glisic ◽  
Tamara Milovanovic

Introduction/Objective. The most common cause of iron deficiency anemia (IDA) in both men and postmenopausal women are gastrointestinal diseases. This study aimed to determine the frequency of pathological and diagnostic findings observed on esophagogastroduodenoscopy (EGDS) and colonoscopy in IDA patients, and examine associations between demographic, anamnestic, and clinical features, with findings found on endoscopy. Methods. A retrospective cross section study of patients with IDA was conducted. Results. Eighty-five patients with IDA were included, mean age of 60.3 ? 18.8 years, with 51.8% being women. Esophagogastroduodenoscopy, colonoscopy, or both was performed in 96.5%, 71.8%, and 70.6% of patients, respectively. The cause of IDA was established in 65.9% of cases. Diagnostic findings were observed in those who underwent EGDS, colonoscopy, or both in 43.9%, 47.5%, and 15.9% of patients, respectively. Diagnostic findings on EGDS were significantly more common in patients older than 50 years then in younger patients (p = 0.031). Patients with a diagnostic finding on colonoscopy more commonly reported weight loss (p = 0.046) and change in bowel habit (p = 0.012), alongside positive fecal occult blood test (FOBT; p = 0.012); they rarely had anemia previously (p = 0.001), rarely used iron supplements (p = 0.022), and were more likely to have malignancy in their past medical history (p = 0.043). Conclusion. Diagnostic findings on EGDS were more commonly observed in older patients, while diagnostic findings on colonoscopy were more common in those with weight loss, change in bowel habit, positive FOBT, and prior malignancy. Colonoscopy was more often diagnostic in patients without anemia or iron supplementation in the past.


PEDIATRICS ◽  
1961 ◽  
Vol 27 (2) ◽  
pp. 199-203
Author(s):  
M. Silvija Hoag ◽  
Ralph O. Wallerstein ◽  
Myron Pollycove

Blood loss from the gastrointestinal tract was measured in 13 infants with iron deficiency anemia, using radioiron as a tracer. The radioiron was given intravenously; radioactivity in the erythrocytes and feces was measured for the following 3 to 4 weeks. The percentage of total Fe administered that was recovered in the stools varied between 0.75 and 16.4%, with a mean of 5.75%. This represents loss of whole blood in the stools varying from 7 to 107 ml, with a mean of 41 ml during the observation period. Occult blood loss from the gastrointestinal tract appears to be a significant factor in the development of iron deficiency in early childhood.


2018 ◽  
Vol 9 (2) ◽  
pp. 137-141
Author(s):  
Gazi Sharmin Sultana ◽  
Syed Aminul Haque ◽  
Ayatunnesa ◽  
Md MA Muttalib ◽  
Md Quddusur Rahman

Background: Detection of iron deficiency early during pregnancy is essential for correct management. Red cell distribution width (RDW) is a new routine parameter in fully automated hematology analyzer that can give the idea of early iron deficiency before Hb%. This study was aimed to see the role of red cell distribution width and Hb% in determining early iron deficiency in pregnant women.Methods: In this study 190 pregnant women were included. CBC including Hb% and RDW and iron profile were done. RDW were compared with Hb% in various stages of iron deficiency.Results: RDW was more significant than Hb level in latent iron deficiency when Hb level was normal (p<0.05). In mild and moderate iron deficiency anemia, RDW was increased progressively though Hb level was reduced. In this study RDW had sensitivity 82.3% and specificity 97.4%. Whereas Hb level had sensitivity 56.6% and specificity 90.9% for iron deficiency.Conclusion: Latent iron deficiency without other complicating disease could be screened out early by increased RDW when Hb% was normal.Anwer Khan Modern Medical College Journal Vol. 9, No. 2: Jul 2018, P 137-141


2020 ◽  
Vol 8 ◽  
pp. 232470962093684
Author(s):  
Faisal Inayat ◽  
Asad Ur Rahman ◽  
Ahsan Wahab ◽  
Amir Riaz ◽  
Effa Zahid ◽  
...  

Inflammatory fibroid polyps (IFPs) are rare mesenchymal lesions that can arise throughout the gastrointestinal tract. These tumors represent less than 0.1% of all gastric polypoid lesions and are frequently found incidentally on endoscopic evaluation. While presenting symptoms depend on the location of the tumor, gastric polyps commonly present with epigastric pain and early satiety. We hereby delineate the case of a middle-aged female who presented with chronic iron deficiency anemia and a positive fecal occult blood test. She underwent an upper endoscopy, which revealed an actively oozing umbilicated lesion in the gastric antrum. Endoscopic ultrasound divulged the submucosal origin of the lesion. It was subsequently excised using endoscopic mucosal resection. Pathologic examination of the resected specimen confirmed the diagnosis of gastric IFP. Furthermore, we conducted a systematic literature search of the MEDLINE database centered on gastric IFPs from January 2000 till March 2020. The data on patient demographics, clinical features, endoscopic findings, lesion site and size, and treatment approaches were collected and analyzed. This article illustrates the overarching need for clinicians to be vigilant of gastric IFPs presenting with initial clinical symptoms suggestive of occult upper gastrointestinal bleeding. Prompt diagnosis and management of gastric IFPs carry paramount importance to combat chronic unexplained iron deficiency anemia following occult bleeding in such patients. A concoction of endoscopy, biopsy, and immunohistochemical examination can be employed toward their prompt detection. Although gastric IFPs have conventionally been treated with surgery, endoscopic resection is now emerging as a safe and efficient therapeutic modality.


1970 ◽  
Vol 37 (3) ◽  
pp. 102-105 ◽  
Author(s):  
GS Sultana ◽  
SA Haque ◽  
T Sultana ◽  
Q Rahman ◽  
ANN Ahmed

Iron deficiency anemia is common problem during pregnancy. Red cell size variation (anisocytosis) is the earliest morphologic changes in iron deficiency anemia. Red cell distribution width is a quantitative measure of red cell size variation and it can give the idea of early iron deficiency before other test to become positive.190 pregnant women were included in this study. Red cell distribution width was compared between iron deficient & non-iron deficient pregnant women. Red cell distribution width also compared with Hb level, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration and peripheral blood film in prelatent iron deficiency, latent iron deficiency, mild and moderate iron deficiency anemia. Red cell distribution width had sensitivity 82.3% and specificity 97.4%. Whereas Hb level, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration and peripheral blood film all had 56.6%, 29.2%, 68.1%, 15% and 38.9% sensitivity but specificity was 90.9%, 98.7%, 83.1%, 96.1% and 98.7% in the detection of iron deficiency. Red cell distribution width appears to be a reliable and useful parameter for detection of iron deficiency during pregnancy. DOI: http://dx.doi.org/10.3329/bmrcb.v37i3.9122 BMRCB 2011; 37(3): 102-105


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