Colorectal cancer in iron deficiency anemia with a positive result on immunochemical fecal occult blood

2000 ◽  
Vol 15 (5-6) ◽  
pp. 271-274 ◽  
Author(s):  
Bing Zhang ◽  
A.S.M. Abdul Fattah ◽  
Xing Zhang ◽  
Hidenori Nakama
Keyword(s):  
Colorectal Cancer ◽  
Iron Deficiency ◽  
Positive Result ◽  
Iron Deficiency Anemia ◽  
Occult Blood ◽  
Deficiency Anemia ◽  
Fecal Occult Blood ◽  
Fecal Occult

scholarly journals Upper and lower gastrointestinal endoscopy in patients with iron deficiency anemia

2020 ◽  
Vol 148 (1-2) ◽  
pp. 31-36
Author(s):  
Dusan Popovic ◽  
Simon Zec ◽  
Ivan Rankovic ◽  
Tijana Glisic ◽  
Tamara Milovanovic
Keyword(s):  
Weight Loss ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Occult Blood ◽  
Gastrointestinal Diseases ◽  
Deficiency Anemia ◽  
Bowel Habit ◽  
Fecal Occult Blood ◽  
Iron Supplements ◽  
Fecal Occult

Introduction/Objective. The most common cause of iron deficiency anemia (IDA) in both men and postmenopausal women are gastrointestinal diseases. This study aimed to determine the frequency of pathological and diagnostic findings observed on esophagogastroduodenoscopy (EGDS) and colonoscopy in IDA patients, and examine associations between demographic, anamnestic, and clinical features, with findings found on endoscopy. Methods. A retrospective cross section study of patients with IDA was conducted. Results. Eighty-five patients with IDA were included, mean age of 60.3 ? 18.8 years, with 51.8% being women. Esophagogastroduodenoscopy, colonoscopy, or both was performed in 96.5%, 71.8%, and 70.6% of patients, respectively. The cause of IDA was established in 65.9% of cases. Diagnostic findings were observed in those who underwent EGDS, colonoscopy, or both in 43.9%, 47.5%, and 15.9% of patients, respectively. Diagnostic findings on EGDS were significantly more common in patients older than 50 years then in younger patients (p = 0.031). Patients with a diagnostic finding on colonoscopy more commonly reported weight loss (p = 0.046) and change in bowel habit (p = 0.012), alongside positive fecal occult blood test (FOBT; p = 0.012); they rarely had anemia previously (p = 0.001), rarely used iron supplements (p = 0.022), and were more likely to have malignancy in their past medical history (p = 0.043). Conclusion. Diagnostic findings on EGDS were more commonly observed in older patients, while diagnostic findings on colonoscopy were more common in those with weight loss, change in bowel habit, positive FOBT, and prior malignancy. Colonoscopy was more often diagnostic in patients without anemia or iron supplementation in the past.

INFECCIÓN POR UNCINARIAS EN UN LACTANTE MENOR: REPORTE DE CASO

2020 ◽  
Vol 31 (1) ◽  
Author(s):  
José Luis Ayala ◽  
Lorena Romero ◽  
Gabriela Cuvi
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Occult Blood ◽  
Transmission Mechanism ◽  
Deficiency Anemia ◽  
Fecal Occult Blood ◽  
Distribution Width ◽  
Tropical Regions ◽  
Digestive Bleeding ◽  
Fecal Occult

Hookworms are endemic nematodes from tropical regions. Infection is more common in preschool and school children, but it is less frequent in infants under 6 months, because of the transmission mechanism that implies contact between contaminated soil and skin. The clinical disease is characterized by manifestations related to iron-deficiency anemia, secondary to a chronic digestive blood loss. An unusual way of presentation is the massive digestive bleeding that causes severe anemia. Case report: A four month shuar girl with no significant medical history, referred from General Puyo hospital, presented upper digestive bleeding of 3 months duration. At month of age, the girl presented self-limited melenas and skin pallor that worsen two weeks before the admission. The girl was hypo active, with a pale complexion, and had edema of feet. Her blood count showed hemoglobin 2.8 g/dl, hematocrit 9%, mean corpuscular volume 73 fl, red cell distribution width 18%, reticulocyte count 1%, eosinophils 4%. Coprological analysis reported tarry stools, positive fecal occult blood test, and hookworm eggs determined by Kato – Katz as a moderate infection. It was diagnosed iron-deficiency anemia secondary to an upper digestive bleeding caused by hookworms. The infection was treated with a single oral dose of albendazole 400mg plus blood transfusion. After 5 days of treatment, hemoglobin increased and edema was reduced. Melenas disappeared completely. Finally the discharge was indicated for outdoor control. Conclusion: Hookworm infestation is an endemic disease whose presence and impact in infants has been underestimated because it is not necessary as a cause of digestive bleeding. This disease should be considered in contexts of endemic areas in children who meet a clinical profile similar to that described.

scholarly journals Immunochemical Fecal Occult Blood Test for Detection of Advanced Colonic Adenomas and Colorectal Cancer: Comparison with Colonoscopy Results

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Bianca Rosa Viana Freitas ◽  
Cristiane Kibune Nagasako ◽  
Celia Regina Pavan ◽  
Sônia Letícia Silva Lorena ◽  
Fabio Guerrazzi ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Sensitivity And Specificity ◽  
Occult Blood ◽  
Fecal Occult Blood ◽  
Screening Programs ◽  
Fecal Occult ◽  
Colonic Adenomas ◽  
Lack Of Information ◽  
Risk Patients ◽  
Advanced Adenomas

Background. Fecal immunochemical tests (FITs) have been used for colorectal cancer (CRC) screening in several countries. There is lack of information concerning diagnostic performances of this method in Brazil.Methods. Patients scheduled for elective colonoscopy provided one stool sample one week before colonoscopy. The accuracy of a qualitative FIT for detection of CRC and advanced adenomas was determined.Results. Overall 302 patients completed the study. Among them, 53.5% were high risk patients referred for screening or surveillance. Nine (3%) CRCs and 11 (3.6%) advanced adenomas were detected by colonoscopy. Sensitivity and specificity for CRC were, respectively, 88.9% and 87.6%. For advanced adenomas, sensitivity was 63.6% and specificity 87.6%.Conclusion. Our results showed good sensitivity and specificity of the FIT for detecting advanced neoplasias. This method may be a valuable tool for future screening programs in Brazil.

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