scholarly journals Long-term effects of early pulse intravenous methylprednisolone or intravenous immunoglobulin in adult patients with dermatomyositis and polymyositis: a large retrospective

2021 ◽  
Author(s):  
Leonardo Santos Hoff ◽  
Fernando Henrique Carlos de Souza ◽  
Renata Miossi ◽  
Samuel Katsuyuki Shinjo
Keyword(s):  
Intravenous Immunoglobulin ◽  
Adult Patients ◽  
Long Term Effects ◽  
Intravenous Methylprednisolone

scholarly journals Results and long-term followup of intravenous immunoglobulin infusions in chronic, refractory polymyositis: An open study with thirty-five adult patients

2002 ◽  
Vol 46 (2) ◽  
pp. 467-474 ◽  
Author(s):  
P. Cherin ◽  
S. Pelletier ◽  
A. Teixeira ◽  
P. Laforet ◽  
T. Genereau ◽  
...  
Keyword(s):  
Intravenous Immunoglobulin ◽  
Open Study ◽  
Adult Patients

Long-term effects of tiagabine monotherapy on cognition and mood in adult patients with chronic partial epilepsy

2006 ◽  
Vol 8 (4) ◽  
pp. 750-755 ◽  
Author(s):  
Marja Äikiä ◽  
Leena Jutila ◽  
Tuuli Salmenperä ◽  
Esa Mervaala ◽  
Reetta Kälviäinen
Keyword(s):  
Partial Epilepsy ◽  
Adult Patients ◽  
Long Term Effects

scholarly journals Left Atrial Volumetric and Deformation Analysis in Adult Patients with Dextro-Transposition of the Great Arteries (Insights from the CSONGRAD Registry and MAGYAR-Path Study)

2020 ◽  
Vol 9 (2) ◽  
pp. 463
Author(s):  
Attila Nemes ◽  
Gergely Rácz ◽  
Árpád Kormányos ◽  
Péter Domsik ◽  
Anita Kalapos ◽  
...  
Keyword(s):  
Left Atrial ◽  
Adult Patients ◽  
Deformation Analysis ◽  
Long Term Effects ◽  
Atrial Contraction ◽  
Functional Features ◽  
Senning Operation ◽  
And Gender ◽  
Mustard Procedure

Background: In complete or dextro-transposition of the great arteries (dTGA), the aorta and the pulmonary artery are transposed. The present study was designed to examine dTGA-associated left atrial (LA) volumetric and functional abnormalities in adult patients late after repair and to compare their results to those of healthy controls. Methods: The present study consisted of 15 dTGA patients (30.3 ± 8.1 years, 9 males), the patients had Mustard (n = 8) or Senning (n = 7) procedure performed. Their results were compared to those of 36 age- and gender-matched healthy subjects (28.7 ± 1.5 years, 24 males). Results: Increased maximum LA volume and reduced LA emptying fractions respecting the cardiac cycle could be demonstrated in our dTGA patients. LA stroke volumes representing all LA functions were significantly reduced. Peak LA circumferential, longitudinal, and area strains and LA circumferential, longitudinal, and area strains measured at atrial contraction were reduced in our dTGA patients. Most LA strains were reduced in patients having Mustard surgery compared to controls and patients undergoing Senning operation. Conclusions: Significant LA volumetric and functional abnormalities could be demonstrated in adult patients with dTGA late after repair. Senning procedure seems to have more beneficial long-term effects on LA volumetric and functional features as compared to the Mustard procedure.

Methylprednisolone treatment in multiple sclerosis: effect of treatment, pharmacokinetics, future

1996 ◽  
Vol 1 (6) ◽  
pp. 327-328 ◽  
Author(s):  
OR Hommes ◽  
F Barkhof ◽  
PJH Jongen ◽  
STFM Frequin
Keyword(s):  
Multiple Sclerosis ◽  
High Dose ◽  
Long Term Effects ◽  
Intravenous Methylprednisolone ◽  
Methylprednisolone Treatment ◽  
Effect Of Treatment

High dose intravenous methylprednisolone treatment is effective and safe in the treatment of relapses in multiple sclerosis, but the long term effects are unclear. Pharmacokinetics are almost unknown, but may be very important for the understanding of the clinical and paraclinical effects. In view of what is known now, IVMP should have a prominent place in basic and clinical MS research.

scholarly journals PREDICTION OF LONG-TERM EFFECTS OF POLYARTICULAR VARIANT OF JUVENILE IDIOPATHIC ARTHRITIS

2018 ◽  
Vol 13 (3-4) ◽  
pp. 28-37
Author(s):  
M.B. Dzhus ◽  
T.V. Marushko ◽  
H.V. Mostbauer ◽  
О.І. Ivashkivsky ◽  
I.V. Kurylchyk ◽  
...  
Keyword(s):  
Risk Factors ◽  
Medical Records ◽  
Prognostic Model ◽  
Surgical Intervention ◽  
Clinical Manifestations ◽  
Binary Logistic Regression ◽  
Response To Therapy ◽  
Adult Patients ◽  
Long Term Effects

Relevance. It is known that the poly-articular variant of JIA is associated with significant articular and extra-articular damages with predominant lesions of small and medium joints with limitation of their function and the development of ankylosis, requiring surgical intervention in these patients. Objective. The aim of the study was to evaluate the risk factors of articular and extra-articular damages in adults with the poly-articular variant of the JIA and to work out a prognostic model for their development. Materials and methods. The study included 45 adult patients with poly-articular (RF+ and RF-) variant of the JIA. Retrospective analysis of medical records of patients with poly-articular variant of JIA was made, taking into account clinical manifestations in the onset of the disease, laboratory parameters and response to therapy. In adulthood, the integral index of articular (JADI-A) and extra-articular (JADI-E) damages was used to assess the long-term effects of JIA. Results. Unfavorable prognostic factors were revealed by method of binary logistic regression. Mathematical model for predicting the probability of long-term negative articular and extra-articular damages of poly-articular JIA was developed. Conclusions 1. The risk factors for the development of articular and extra-articular damages in adulthood in patients with a poly-articular variant of the JIA are female sex, the presence of lymphadenopathy and/or splenomegaly in childhood, the level of ESR during treatment in childhood, the activity of JADAS in childhood, the presence of symmetric arthritis in childhood, the RF positivity in the debut of the disease, the treatment with glucocorticoids, the cumulative dose of the DMARDs, and lack of therapy by DMARDs. 2. A prognostic model for the development of articular and extra-articular damages in adult patients with a poly-articular variant of the JIA is developed. This model is effective and allows determine the adverse course of the disease and can be the basis for personalized treatment for the prevention of the development of significant articular and extra-articular damages of JIA.

Long-term effects of intravenous immunoglobulin in CIDP

2007 ◽  
Vol 118 (9) ◽  
pp. 1980-1984 ◽  
Author(s):  
S. Vucic ◽  
K. Black ◽  
L.E. Baldassari ◽  
P. Siao Tick Chong ◽  
K.T. Dawson ◽  
...  
Keyword(s):  
Intravenous Immunoglobulin ◽  
Long Term Effects
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