Can Rhythmic Sensory Stimulation Decrease Cognitive Decline in Alzheimer's Disease?: A Clinical Case Study

2017 ◽  
Vol 9 (3) ◽  
pp. 174
Author(s):  
Amy Clements-Cortes ◽  
Lee Bartel ◽  
Heidi Ahonen ◽  
Morris Freedman ◽  
Michael Evans ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Sensory Stimulation ◽  
Longitudinal Case Study ◽  
Term Care ◽  
Clinical Case Study ◽  
Gamma Frequency ◽  
Frequency Entrainment ◽  
New Treatment

Background/Objectives: To present Rhythmic Sensory Stimulation (RSS) as a potential new treatment of Alzheimer’s disease (AD).Design: Longitudinal case study over a three year period.Setting: RSS was provided both in a long-term care/research facility and in-home.Participant:  One 92 year old female with AD.Intervention: Treatments consisted of RSS resulting in gamma frequency entrainment, provided by two different treatment devices over three years.Measurements: Quantitative and qualitative measures were used including: MMSE, SLUMS, interviews, observation notes and a participant question sheet.Results: MMSE scores since diagnosis three years earlier, as well as cognition, clarity, and awareness were reported by the case’s husband to have remained unchanged.Conclusion: Although further research is warranted, this case suggests that RSS has potential to help maintain cognition in AD. 

scholarly journals Rhythmic auditory stimulation rescues cognitive flexibility in mutant mice with impaired gamma synchrony

2021 ◽  
Author(s):  
Jingcheng Shi ◽  
Aarron J Phensy ◽  
Vikaas Singh Sohal
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Sensory Stimulation ◽  
Auditory Stimulation ◽  
Invasive Treatment ◽  
Non Invasive ◽  
Gamma Frequency ◽  
Gamma Synchrony ◽  
Circuit Function ◽  
40 Hz

Neural synchronization at gamma (~40 Hz) frequencies is believed to contribute to brain function and be deficient in disorders including Alzheimer's disease and schizophrenia. Gamma-frequency sensory stimulation has been proposed as a non-invasive treatment for deficient gamma synchrony and associated cognitive deficits, and has been shown to be effective in mouse models of Alzheimer's disease. However, both the mechanism and applicability of this approach remain unclear. Here we tested this approach using mutant (Dlx5/6+/-) mice which have deficits in gamma synchrony and the ability to learn to shift between rules which use different types of cues to indicate reward locations. 40 Hz auditory stimulation rescues rule shifting in Dlx5/6+/- mice. However, this improvement does not outlast the period of stimulation, and is not associated with normalized gamma synchrony, measured using genetically encoded voltage indicators. These results show how gamma-frequency sensory stimulation may improve behavior without fully restoring normal circuit function.

The Applicability and Effect of EMDR in a Patient With a Mild Stage of Alzheimer's Disease

2019 ◽  
Vol 13 (1) ◽  
pp. 51-60
Author(s):  
Martje van der Wielen ◽  
Hanneke Robben ◽  
Ruth E. Mark
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Clinical Case ◽  
Stress Disorder ◽  
Life Experiences ◽  
Traumatic Memory ◽  
Clinical Case Study ◽  
Self Reports ◽  
Emdr Therapy

Eye movement desensitization and reprocessing (EMDR) therapy is recognized worldwide as an effective treatment for the symptoms of posttraumatic stress disorder (PTSD) and all kinds of adverse life experiences. The literature on the clinical usefulness of EMDR therapy in people with Alzheimer's disease is scarce. We present a clinical case study of a woman who was recently diagnosed with Alzheimer's disease. This patient was suffering from daily flashbacks of her institutionalized mother in a later stage of dementia. According to self-reports, one session of EMDR therapy alleviated the distress associated with her traumatic memory. We discuss the applicability of the EMDR protocol for people with Alzheimer's disease and highlight possible limitations and adaptations.

scholarly journals Opieka pielęgniarska nad pacjentką w przebiegu choroby Alzheimera z wykorzystaniem ICNP®

2020 ◽  
Vol 5 (3) ◽  
pp. 97-115
Author(s):  
Karolina Krajewska ◽  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Holistic Approach ◽  
Female Gender ◽  
Control Field ◽  
Her Family ◽  
Everyday Activities ◽  
Nurse Caring ◽  
It Risk

Introduction. Alzheimer's disease (AD – Alzheimer Disease) is an incurable neurodegenerative disease. The main source of memory discomfort is destruc-tion. With age, irresistibly falling ill with it. Risk factors for the development of Alzheimer's disease are primarily: diabetes, female gender, hypertension and the lack of a control field. It is estimated that in Poland Alzheimer's disease affects about 200,000 people. According to statistics, 60% of all forms of de-mentia are AD. Aim of the study. The aim of the study is to present the activities that should be performed by a nurse caring for a patient with diagnosed Alzheimer's dis-ease. Case study. A 75-year-old patient admitted to the internal medicine ward, she has communication, content swallowing and spatial orientation disorders. It requires constant assistance in the performance of everyday activities. He complains of urinary and faecal incontinence. Conclusion. Thanks to the holistic approach to the patient, it is possible to ensure her correctness and the approach of the patient and her family.

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