scholarly journals Role of Histopathological Analysis in Diagnosing Steroid Cell Tumour: A Case Report

2019 ◽  
Vol 2 (1) ◽  
pp. 91-94
Author(s):  
S R Ohayi

Steroid cell tumour of the ovary is an extremely rare tumour. They are classified into three types with the commonest, the steroid cell tumour not otherwise specified (NOS) consisting approximately 60% of them. They occur mostly in middle age, are mostly benign and mostly cause virilising symptoms though a small proportion can present with oestrogenic effects. Diagnosis is based on presence of symptoms, presence of specific histopathological features with absence of certain histopathological features and positive specific immunostaining results. Here the author reports a case of a 42-year old woman with abdominal mass but without virilising symptoms but on whom a diagnosis of ovarian steroid cell tumour was reached by histopathological analysis which revealed presence of specific histopathological features with absence of certain histopathological features.

2019 ◽  
Vol 2 (1) ◽  
pp. 91-94
Author(s):  
S R Ohayi

Steroid cell tumour of the ovary is an extremely rare tumour. They are classified into three types with the commonest, the steroid cell tumour not otherwise specified (NOS) consisting approximately 60% of them. They occur mostly in middle age, are mostly benign and mostly cause virilising symptoms though a small proportion can present with oestrogenic effects. Diagnosis is based on presence of symptoms, presence of specific histopathological features with absence of certain histopathological features and positive specific immunostaining results. Here the author reports a case of a 42-year old woman with abdominal mass but without virilising symptoms but on whom a diagnosis of ovarian steroid cell tumour was reached by histopathological analysis which revealed presence of specific histopathological features with absence of certain histopathological features.


2019 ◽  
Vol 2 (1) ◽  
pp. 91-94
Author(s):  
S R Ohayi

Steroid cell tumour of the ovary is an extremely rare tumour. They are classified into three types with the commonest, the steroid cell tumour not otherwise specified (NOS) consisting approximately 60% of them. They occur mostly in middle age, are mostly benign and mostly cause virilising symptoms though a small proportion can present with oestrogenic effects. Diagnosis is based on presence of symptoms, presence of specific histopathological features with absence of certain histopathological features and positive specific immunostaining results. Here the author reports a case of a 42-year old woman with abdominal mass but without virilising symptoms but on whom a diagnosis of ovarian steroid cell tumour was reached by histopathological analysis which revealed presence of specific histopathological features with absence of certain histopathological features.


2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Sara L. Schaefer ◽  
Amy L. Strong ◽  
Sheena Bahroloomi ◽  
Jichang Han ◽  
Michella K. Whisman ◽  
...  

Abstract Background Lipoleiomyoma is a rare, benign variant of the commonplace uterine leiomyoma. Unlike leiomyoma, these tumors are composed of smooth muscle cells admixed with mature adipose tissue. While rare, they are most frequently identified in the uterus, but even more infrequently have been described in extrauterine locations. Case presentation We describe a case report of a 45-year-old woman with a history of in vitro fertilization pregnancy presenting 6 years later with abdominal distention and weight loss found to have a 30-cm intra-abdominal lipoleiomyoma. While cross-sectional imaging can narrow the differential diagnosis, histopathological analysis with stains positive for smooth muscle actin, desmin, and estrogen receptor, but negative for HMB-45 confirms the diagnosis of lipoleiomyoma. The large encapsulated tumor was resected en bloc. The patients post-operative course was uneventful and her symptoms resolved. Conclusions Lipoleiomyoma should be considered on the differential diagnosis in a woman with a large intra-abdominal mass. While considered benign, resection should be considered if the mass is symptomatic, and the diagnosis is unclear or there is a concern for malignancy.


2021 ◽  
Vol 11 (1) ◽  
pp. 1891-1894
Author(s):  
Irene Thomas ◽  
Divya Surendran ◽  
Joy Augustine

Mixed adenoneuroendocrine carcinoma is a rare neoplasm with both epithelial and neuroendocrine components. To date, only a few cases of this neoplasm have been reported in the literature among which gastric mixed adenoneuroendocrine carcinoma is very rare. We are reporting a case of gastric mixed adenoneuroendocrine carcinoma with squamous cell differentiation. Histopathological features, biological behaviour and the treatment of this rare tumour type have been discussed briefly.


Author(s):  
Fathima Seles M. ◽  
M. Revathy ◽  
Madurai Padmanabhan Kanchana

Virilising ovarian tumours account for less than 5% of all ovarian tumours. A steroid cell tumour (SCTs) of the ovary comes under the sex cord stromal tumours and accounts for only 0.1% of all ovarian tumours. Almost 75% are functioning tumors with production of androgenic hormones causing virilisation and cushingoid features. They are usually unilateral, benign with only 25-45% malignant cases. Here authors report the incidence of steroid cell tumour in our institution and discuss about a 37-year-old woman with steroid cell tumour, not otherwise specified who presented with oligomenorrhea followed by amenorrhea, secondary infertility and signs of virilisation.


Pathology ◽  
2018 ◽  
Vol 50 ◽  
pp. S143
Author(s):  
B.M. Allanson ◽  
E.R. Allanson ◽  
S. Saidi ◽  
C.J.R. Stewart ◽  
W. Foulkes ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Asad Jehangir ◽  
Kyle Bennett ◽  
Shoaib Bilal Fareedy ◽  
Andrew Rettew ◽  
Bilal Shaikh ◽  
...  

IgG deficiency can predispose to recurrent pyogenic infections. The association of IgG deficiency withClostridium difficileinfection has been infrequently reported in the literature. We present a case of a middle-age woman with multiple hospitalizations for recurrentC. difficilein a short span of time which prompted consideration of a possible fecal transplant. On evaluation, she was found to have low total IgG, with subclass analysis revealing low IgG1 and IgG3. She was started on monthly infusions of immunoglobulins and one year after her last episode ofC. difficileshe has not had any recurrence. The role of immunoglobulin infusion in the treatment of recurrentC. difficileis controversial, with some studies revealing no clear evidence of benefit. Our case report suggests that the patients who have underlying IgG deficiency may benefit from immunoglobulin, as this can significantly reduce the incidence of recurrent infections and hence save the healthcare costs.


2003 ◽  
Vol 33 (3) ◽  
pp. 317-322 ◽  
Author(s):  
Cynthia L. Baxter ◽  
William D. White

Coma is present when the patient appears asleep, is unrousable, and unresponsive. Where no underlying medical condition is found, the role of the psychiatrist may become prominent. We present a clinical case and review the literature on psychogenic coma. According to DSM-IV-TR, psychogenic coma is a dissociative disorder not otherwise specified. Management is largely supportive. Principles include speaking in a reassuring manner and avoiding repeated painful stimuli. Education of family and other professionals that symptoms are real and not consciously feigned may be important. There may be a short-term role for anxiolytic and/or antipsychotic medication to assist return to consciousness.


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