scholarly journals MANAGEMENT OF MALE INFERTILITY (OLIGOASTHENOZOOSPERMIA) WITH AYURVEDA

2020 ◽  
Vol 8 (10) ◽  
pp. 4902-4905
Author(s):  
Shivani Karnwal
Keyword(s):  
Male Infertility ◽  
Male Patient ◽  
Sperm Count ◽  
Semen Analysis ◽  
Male Partner ◽  
Unprotected Intercourse ◽  
Fertile Female ◽  
Ayurvedic Drugs ◽  
Motility Of Sperm ◽  
Diagnostic Investigations

Male infertility refers to a male’s inability to cause pregnancy in a fertile female. There are many reasons that aid the pathology of male infertility primary includes low sperm count, volume, motility, abnormality in shapes and few reproductive dysfunctions. Oligoasthenozoopsermia which is one of the major causes behind male infertility comprises two conditions – Oligospermia (low sperm count) and Asthenozoo-spermia (reduced motility of sperm).Researches reveals that 1 in every 3 cases of infertility are due to the male partner so nowadays diagnosis and management of both the partners is now considered as a vital tool. In this article, I report a case of a 30-year-old male patient with complaints of wanting an issue after a complete year of regular, unprotected intercourse. For which he had undergone all the regular diagnostic investigations of his wife, which reported no issues and recorded with regular and ovulatory cycles with patent tubes. Then progressing in the diagnosis, he had undergone a semen analysis and got diagnosed with Oligoasthenozoospermia. The issue was successfully treated with Ayurvedic drugs within a period of 1 month.

scholarly journals Prevalence and Patterns of Male Infertility Based on Semen Analysis in Patients Visiting Massawa Hospital; Eritrea: Cross-Sectional Study; 2020

2021 ◽  
Author(s):  
Berhe Tesfai ◽  
Fitsum Kibreab ◽  
Hailemichael Gebremariam ◽  
Liwam Abraham
Keyword(s):  
Male Infertility ◽  
Sperm Motility ◽  
Sperm Count ◽  
Semen Analysis ◽  
Male Factor Infertility ◽  
Male Factor ◽  
Cross Sectional ◽  
Semen Volume ◽  
Primary Type ◽  
Study Participants

Abstract Background Semen analysis is the first step to identify male factor infertility. World Health Organization estimates that male factor accounts for 50% of couple sub-fertility. The objective of this study was to determine the prevalence and patterns of male factor infertility based on semen analysis in patients visiting Massawa Hospital with infertility complaints. Methods It was a retrospective, descriptive cross sectional hospital based type of study with a census sampling method. Patient’s medical records and hospital laboratory register were used to retrieve semen analysis results of patients from June 2018 to June 2020. Ethical approval was obtained from the Ministry of Health Research and Ethical Review Committee. Confidentiality of patients records kept was secured and consent was obtained from study participants to use their data. Results were presented in frequency, tables and p value < 0.05 was considered significant. Results A total of 112 patients data was analyzed in the study with 49.1% were aged between 20 to 30 years. The prevalence of male factor infertility in these patients was found to be 42% and 79.5% of them had primary type of infertility. Of the study participants; 63 (56.3%), 72 (64.3%) and 70 (62.5%) had sperm count < 15 million sperms/ml, sperm motility < 40 % and morphology of < 60% respectively. One tenth, 15 (13.4%) of the patients had a semen volume of < 1.5ml/ejaculate, out of which 13(86.7%) had primary type of infertility. Moreover; 72 (64.3%) patients had total sperm count/ejaculate of < 39 million and 59 (82%) of these had primary type of infertility. In addition; 50.8% and 50% of patients aged 20 to 30 years had a sperm count < 15 million/ml and sperm motility of < 40% respectively. Conclusion The prevalence of male factor infertility was slightly higher and was dominated with primary infertility. Most patients had lower sperm count, sperm motility but higher semen volume, and majority of the patients with abnormal sperm results were aged between 20 to 30 years. Further prospective researches to determine the risk factors for male infertility and introducing assisted type of fertility in Eritrea are highly recommended.

scholarly journals The possible association of clusterin fucosylation changes with male fertility disorders

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ewa Janiszewska ◽  
Izabela Kokot ◽  
Iwona Gilowska ◽  
Ricardo Faundez ◽  
Ewa Maria Kratz
Keyword(s):  
Male Infertility ◽  
Blood Serum ◽  
Seminal Plasma ◽  
Male Fertility ◽  
Sperm Count ◽  
Semen Analysis ◽  
Infertile Men ◽  
Abnormal Sperm ◽  
Fertility Disorders ◽  
Oligosaccharide Structures

AbstractIn the seminal plasma (n = 118) and serum (n = 90) clusterin (CLU) the fucosylation and the expression of selected fucosyltransferases (FUTs) were analyzed. Samples from infertile men were divided into groups based on the results of the standard semen analysis: normozoospermic (N), teratozoospermic (T), asthenoteratozoospermic (AT) and oligoasthenoteratozoospermic (OAT). The CLU fucosylation was analyzed using lectin-ELISAs with biotinylated lectins specific to α1,3-, α1,2-linked antennary fucose, and α1,6-linked core fucose (LTA, UEA, and LCA, respectively). The concentrations of FUT3 and FUT4, reflecting the expression of Le oligosaccharide structures, were measured using ELISA tests. The differences in serum CLU and FUT4 concentrations, and in the expression of core fucose and antennary fucose α1,2-linked in CLU glycans between the N group and other groups examined suggest that the disturbances in sperm count, motility, and morphology are not the only cause of male infertility. Lack of similarities between levels of examined parameters in blood serum and seminal plasma may suggest the differences in mechanisms leading to glycoproteins glycosylation. It confirmed the observed differences in concentrations of seminal plasma CLU, FUT3, and FUT4 between the OAT group and N, T, AT groups, indicating that decreased sperm count may be related to these parameters expression. The serum CLU concentrations and expression of core fucose and fucose α1,2-linked in CLU, seem to be good markers differentiating normozoospermic men from those with abnormal sperm parameters, which was not observed for seminal plasma.

scholarly journals Prevalence of Male Infertility among the Infertile Couples Attended at BIRDEM General Hospital, Dhaka

2018 ◽  
Vol 6 (1-2) ◽  
pp. 25-32
Author(s):  
Fahmin Rahman ◽  
Mohiur Rahman ◽  
Nusrat Mahmud ◽  
GU Ahsan ◽  
Mitheel Ibna Islam
Keyword(s):  
Male Infertility ◽  
General Hospital ◽  
Reproductive Tract ◽  
Semen Analysis ◽  
Male Partner ◽  
Male Partners ◽  
Male Factor ◽  
Obesity And Diabetes ◽  
Infertile Couples ◽  
Tract Infections

Background & objective: Infertility is a problem of public health importance because of its high prevalence and serious social implications on affected couples and families. Although once believed that the problem is solely due to female factor, it is now generally accepted that male factor infertility is equally as important as the female factor. However, it is not known how far the problem is attributed to male factor. The present study is intended to find the prevalence of male infertility among the infertile couples and its determinants in the context of Bangladeshi population. Patients & Methods: The present study was a descriptive cross-sectional study conducted on male partners of infertile couples (over a period of three months) visiting the Infertility Clinic of Bangladesh Institute of Research and Development in Endocrine & Metabolism (BIRDEM) General Hospital, Dhaka. Male infertility was defined as the inability of a man to make his partner conceive (because of quantitative and/or quantitative deficiency of his sperm) after 12 months of regular unprotected sexual intercourse. On the basis of semen analysis, male partners were divided into two groups – Infertile Group and Fertile Group and the suspected factors were compared between groups using crosstab analysis to determine the factors responsible for male infertility. Result: The present study demonstrated that respondents were generally middle aged (between 30-50 years) with mean age being 35.5 years. Majority (88.5%) was Muslim and belonged to middle class (74.3%). Nearly half (47%) was service-holder and one-third (35.8%) was businessman. About 62% of the male partners were revealed to be infertile on semen analysis [combined prevalence of azoospermia (19%), asthezoospermia (29.2%) oligospermia (12.8%), and teratzoospermia (7.1%)]. Of them nearly one-third (azoospermic ones) was solely responsible for infertility and the rest played contributing role to the overall infertility. The reproductive tract infection (STDs) was reported to be alarmingly high among infertile males (21.4%) than that among their fertile peers (p = 0.002). Smoking, varicocele, overweight or obesity and diabetes also demonstrated their significant presence among infertile males compared to the fertile male group. History of occupational exposure to high temperature, pesticide, trauma to testes, abdominal and urogenital surgery were not associated with male partner fertility. Conclusion: From the findings of the present study, it can be concluded that a substantial proportion of infertility can be attributed due to male partner infertility and its significant predictors are reproductive tract infections or sexually transmitted diseases. The second leading causes are varicocel, diabetes and obesity. Ibrahim Card Med J 2016; 6 (1&2): 25-32

scholarly journals Influence of Lifestyle and Environmental Factors on Semen Quality in Ghanaian Men

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Richard Michael Blay ◽  
Abigail Duah Pinamang ◽  
Augustine E. Sagoe ◽  
Ewurama Dedea Ampadu Owusu ◽  
Nii Koney-Kwaku Koney ◽  
...  
Keyword(s):  
Environmental Factors ◽  
Male Infertility ◽  
Sperm Motility ◽  
Semen Quality ◽  
Sperm Quality ◽  
Sperm Count ◽  
Semen Analysis ◽  
Reproductive Age ◽  
Adult Males ◽  
Lifestyle Habits

Introduction. Male infertility is known to contribute about half of all infertility cases. In Ghana, the prevalence of male infertility is higher (15.8%) than in females (11.8%). Sperm quality is associated with the likelihood of pregnancy and known to be the cause of male fertility problems 90% of the time. Exposure to certain environmental factors reduces semen quality in men. The study examined the effects of environmental and lifestyle factors on semen quality in Ghanaian men. Materials and Methods. This was a cross-sectional study involving 80 apparent healthy adult males in their reproductive age. Participants were males referred to the laboratory (Immunology Unit of the Korle-Bu Teaching Hospital) for semen analysis test and/or culture and sensitivity. Participants were made to fill out a questionnaire which entailed selected environmental factors (accidents or trauma, exposure to chemicals, radiation, and heat) and lifestyle habits (including alcohol consumption, smoking, and whether participants sat more or less than 4 hours per day). Semen samples were then collected by masturbation into sterile containers and analysed in accordance with WHO guidance for semen analysis within 60 minutes after ejaculation and collection. Results. About 69% of participants had semen pH within the normal range compared to 15% whose pH were lower than 7.2. There was a significantly high number of immotile sperm cells ( p value = 0.017) in participants who sat for more than 4 hours as compared to those that sat for less than 4 hours in a day. Active sperm motility and viability showed significant increase ( p value = 0.002 and 0.009, respectively) in participants who kept their cell phones in their side pockets. Smoking produced a twofold decrease in sperm count as smokers had a significantly lower sperm count ( 12.28 ± 10.95 × 10 6 /ml) compared to the smoke-free ( 23.85 ± 22.14 × 10 6 /ml). For exposure to STDs, no significant differences were recorded among study groups concerning semen quality. Conclusion. Sperm quality in Ghanaian men is associated with lifestyle habits. Smoking and sitting for long hours influenced sperm motility and count, respectively. Knowledge of the factors that influence sperm quality in this geographical region can contribute to informed decisions on effective management of infertility in Ghanaian men.

scholarly journals Risk Factors Analysis for Abnormal Semen Characteristics in Sub-Fertile Male

2019 ◽  
Vol 31 (1) ◽  
pp. 31-35
Author(s):  
Afroza Akhter ◽  
Liza Chowdury ◽  
Mahbuba Akhter ◽  
Samira Haque
Keyword(s):  
Risk Factors ◽  
Sperm Count ◽  
Semen Analysis ◽  
Male Partner ◽  
Semen Parameters ◽  
Military Hospital ◽  
Surgical Trauma ◽  
Heavy Smoking ◽  
Sperm Abnormality ◽  
The Mean

Introduction: This study aimed to identify the risk factors for abnormal semen parameters in male partner of sub-fertile couples. Materials & Methods: This was a prospective study of 100 diagnosed infertile & sub-fertile couples in the age group between 23-58 yrs old male were from 1st March 2013 to 28th Feb 2014 treated in Dhaka Combined Military Hospital (CMH). On the basis of sperm count the cases were grouped as follows. normozoospermia, oligozoospermia & azoospermia. Semen analysis was done in all the cases, The results were described with arithmetic mean and standard deviation. Male partners with normal semen parameters was undertaken among the sub-fertile couples attending the General Outpatient Department (GOPD) of CMH Dhaka. The history was taken from selected individual and it includes personal, socio-economics, occupational, medical, surgical history and drug intake to find out risk factors for abnormal semen parameters. Results: In Normozoospermia mean and SD of sperm count, sperm abnormally, sperm motillity were 65.98±5.05, 24.44±1.57 and 45.5±2.94 respectively. In 0ligozoospermia the mean and SD of sperm count, sperm abnormality, sperm mtility were 7.74±1.23, 41.1±3.78, 14.54±2.77 respectively. In azoospermia the mean and SD of sperm count, sperm abnormality, sperm motility were absent. Conclusion: Here data statistically showed person with normozoospermia having good sperm morphology & motility than oligozoospermia and azoospermic subjects thereby causing male infertility which was responsible for hindrance in achieving pregnancy clinically. Using tight undergarment or working in hot atmosphere depresses spermatogenesis. Mumps orchitis permanently damage spermatogenesis. Bacterial or viral infection depresses the sperm count. Diabetes, malnutrition, heavy smoking reduces spermatogenesis. β-blocker, antihypertensive were likely to hinder spermatogenesis. The efferent ducts might be obstructed by infection like tubercular, gonococcal or by surgical trauma. Medicine Today 2019 Vol.31(1): 31-35

AYURVEDIC MANAGEMENT OF KSHEENA SHUKRA (OLIGOSPERMIA) LEADING TO MALE INFERTILITY: A CASE REPORT

2021 ◽  
Vol 12 (4) ◽  
pp. 30-32
Author(s):  
Akhilraj A R ◽  
Amalraj A R
Keyword(s):  
Case Report ◽  
Male Infertility ◽  
Conventional Medicine ◽  
Sperm Count ◽  
Semen Analysis ◽  
World Health ◽  
Case Discussion ◽  
Ayurvedic Treatment ◽  
Health Organization

As per the World Health Organization (WHO) report in India, the overall prevalence of primary infertility ranges between 3.9 to 16.8%. A recent report on status of infertility states that, 50% is related to reproductive anomalies or disorders in the male, in which 90% of male infertility problems are related to Oligospermia and other abnormalities in semen analysis. As per Ayurveda, Oligospermia can be considered as Ksheena Shukra. Surgery, Hormone treatments, Medications and Assisted Reproductive Technology (ART) are the main line of treatment in Conventional medicine, but these are associated with many unwanted and serious adverse effects. The present case discussion is about the effective management of a case diagnosed as Ksheena Shukra (Oligospermia) with Ayurvedic intervention, which was posted for ART and Hormone therapy. The aim of this case report is to evaluate the effect of Ayurvedic treatment in the management of Ksheena Shukra. In this case study, Shodhana procedures (especially Virechana karma) were performed before the administration of Rasayana and Vajikarana drugs, which are Narasimha rasayana, Bhringarajasavam, Ashwagandha churna. The pre and post Semen analysis on the treatment period shows, marked increase in sperm count and motility. The outcome of this case reveals that the Oligospermia associated with male infertility can be effectively managed by Ayurvedic treatments.

scholarly journals Role of Male Partners in 100 Infertile Couples

2016 ◽  
Vol 11 (1) ◽  
pp. 50-53
Author(s):  
Mah Jabeen Ara ◽  
Sk Md Bahar Hussain ◽  
Mamun Ur Rashid
Keyword(s):  
Male Infertility ◽  
Sperm Motility ◽  
Sperm Morphology ◽  
Sperm Count ◽  
Semen Analysis ◽  
Armed Forces ◽  
Medical College ◽  
Sperm Abnormality ◽  
A Prospective Study

Introduction: Approximately 15% of couples are infertile. Male infertility plays an important role in about half of these couples. This study has been done to determine whether sperm morphology and motility do really affect sperm count or spermatogenesis and at the same time causes a problem with fertility.Objectives: The objective of this study was to evaluate a male’s inability to cause pregnancy in a fertile female.Materials and Methods: This is a prospective study of 100 diagnosed infertile and subfertile couples in the age group of 23-58 yrs old male. They were selected from 01 March 2013 to 28 Feb 2014 undergoing treatment for infertility in Dhaka CMH. On the basis of sperm count the cases were grouped as follows: Normozoospermia, oligozoospermia & Azoospermia. Semen analysis was done in all the cases and the results were described with arithmetic mean and standard deviation.Results: Normozoospermia: Mean and SD of sperm count, sperm abnormality, sperm motility are 65.98± 5.05, 24.44±1.57 and 45.5±2.94 respectively; Oligozoospermia: Mean and SD of sperm count, sperm abnormality, sperm motility are 7.74±1.23, 41.1±3.78, 14.54±2.77 respectively; Azoospermia: Mean and SD of sperm count, sperm abnormality, sperm motility are absent.Conclusion: Here data statistically showed person with normozoospermia having good sperm morphology and motility than oligozoospermia and azoospermic subjects thereby causing male infertility which is responsible for hindrance in achieving pregnancy clinically.Journal of Armed Forces Medical College Bangladesh Vol.11(1) 2015: 50-53

scholarly journals Management of Male Infertility Caused by Oligospermia Using Ayurveda: A Case Report

AYUSHDHARA ◽  
2021 ◽  
pp. 3453-3456
Author(s):  
Suyesh Partap Singh ◽  
Manish Grover ◽  
Ajeet Partap Singh
Keyword(s):  
Case Report ◽  
Male Infertility ◽  
Sperm Count ◽  
Married Couple ◽  
Life Styles ◽  
Ayurvedic Drugs ◽  
Diet Regimen ◽  
Strict Diet ◽  
Altered Physiology ◽  
Ayurvedic Treatment

In India, 1 out of 10 couples suffers from infertility are owing to impaired spermatozoa production or its function, impaired sperm delivery, improper ejaculation, due to sedentary life styles and day to day stress nowadays. Male infertility can be defined as an inability to induce conception, due to defect in spermatozoic functions like low sperm count, unhealthy sperm production, low sperm motility and altered delivery of sperms due to altered physiology of male reproductive system. A 29-year-old married man was diagnosed with oligospermia, visited Shuddhi Ayurveda Clinics, Noida for his condition management and treated successfully with Ayurvedic drugs. This married couple was facing infertility issue from last 2-3 years. Patient was treated with Ayurvedic drugs and kept on strict diet monitoring for four months and results were counted in terms of improved total sperm count after treatment. Before treatment sperm count was 10 million per ml which got improved up to 90 million per ml after four months of Ayurvedic treatment with strict diet regimen. No any side effects were observed during the treatment period. Other morphological parameters of sperm were also found to be healthy and normal for fertility. From the results of this case report, Ayurvedic treatment is proved to be effective in the treatment of male infertility associated with oligospermia.

scholarly journals ROLE OF SONOGRAPHY IMAGING IN MALE INFERTILITY

2019 ◽  
Vol 3 (10) ◽  
Author(s):  
Dr. Rajnikant Narsinhbhai Chauhan ◽  
Dr. Dileep Kumar Jha
Keyword(s):  
Male Infertility ◽  
Clinical Examination ◽  
Semen Quality ◽  
Sperm Count ◽  
Semen Analysis ◽  
Transrectal Ultrasound ◽  
P Value ◽  
Obstructive Azoospermia ◽  
Unprotected Sexual Intercourse ◽  
Left Lateral Decubitus Position

Introduction: Infertility is known as major problem as life crisis for many couples. Investigation of male infertility is assuming greater importance with male factors implicated as it caused half of the infertile couples. Infertility is defined as infertility is a disease of reproductive system defined by failure to achieve the clinical pregnancy after 12 months or more of regular unprotected sexual intercourse. It is also define as failure of couple to conceive after 12 months of regular intercourse without the use of contraception in women <35 years; and regular intercourse after 6 months without the use of contraception in women ≥ years. A recent report on the status of infertility in India, states that nearly 50% of infertility is related to the reproductive anomalies or disorders in the male. Male infertility include as pretesticular, testicular and post testicular causes. Common causes may be due to deficiencies in the semen and semen quality is used as a surrogate measure of male fecundity. Testicular causes are mainly cryptorchidism, varicocele exposure to gonadotoxins and post testicular causes which included disorders and obstruction of ejaculation and erectile dysfunction. There are many studies which found that sperm count of less than 10 million per milliliter is also suboptimal for fertility; however there is no cut off value of sperm count that is diagnostic of infertility. The common investigations done in evaluating fertility is Ultrasound examinations of scrotum and semen analysis. Ultrasound is a very useful modality for assessing the testicular size which is also related to condition like epididymo-orchitis, varicocele and undescended testis. Aim: The main aim of this study is to deteremine the used of ultra sonography in the evaluation of male infertility and to compared with clinical and surgical findings. Material and Methods: All the patients were referred to the Department of Radiology for transrectal and scrotal ultrasonography with high frequency transducer having a frequency of 7.5 MHz and Color Doppler wherever indicated. In this study all male patients with infertility and abnormal semen analysis and with the case of infertility with coincident scrotal findings on clinical examination were included. Transrectal ultrasound was done by positioned in left lateral decubitus position. On each side testis and epididymis was identified as completely as possible and compared for symmetry, size, texture and vascularity. Result: In this study patients with abnormality were found in highest number on clinical palpation and ultrasound was varicocele. In 18 cases Varicocele was detected on clinical examination and 24 cases in ultrasound. In 9 cases Hydrocele was detected in clinical examination and Ultrasound. In 5 cases epididymal cysts were detected in clinical findings and 6 cases were found in Ultrasound Findings whereas 2 cases of epididymitis  was found in ultrasound and only 1 case in clinical examination. Therefore the total number of abnormalities was found by ultrasound which was significantly greater as compared to physical examination. The p-value was 0.001 which shows statistically significant. Conclusion: Transrectal ultrasound enables high resolution imaging of prostate, seminal vesicles and distal vas deferens and is implicated in diagnosing the cause of obstructive azoospermia. Therefore Imaging plays an important complementary role to clinical examination and laboratory analyses for the detection of precise anatomy and level of abnormality.  Hence transrectal and scrotal ultrasound provides valuable information in the diagnostic evaluation of infertile men and pathological conditions can be detected on ultrasound compared to clinical palpation. Keywords: Infertility, Sonography, Transrectal, Testicular

Comparison of Open Sub-Inguinal and Microscopic Sub-Inguinal Varicocelectomy for Improvement of Sperm Parameters

2021 ◽  
Vol 15 (10) ◽  
pp. 2882-2885
Author(s):  
Saleem Shahzad ◽  
Muhammad Waqar Shahid ◽  
Muhammad Azeem Mughal ◽  
Ismat Ullah ◽  
Attiq-ur- Rehman Khan
Keyword(s):  
Male Infertility ◽  
Sperm Count ◽  
Semen Analysis ◽  
Semen Parameters ◽  
Surgical Methods ◽  
Group A ◽  
Treatment Objective ◽  
Randomized Controlled Trail ◽  
Group B ◽  
Keywords Male Infertility

Background: Varicoceles along with oligospermia as well as with asthenozoospermia lead to the male infertility. It can weaken the spermatogenesis via many different pathophysiological mechanisms. Many surgical and non-surgical methods are available for its treatment. Objective: To compare microscopic versus open sub-inguinal varicocelectomy in males with varicocele with oligospermia and asthenozoospermia. Study Design: Randomized controlled trail Place and Duration of Study: Department of Urology, Lahore General Hospital, Lahore from 1st May to 30th November 2017. Methodology: One hundred and fifty males with varicocele were recruited and divided in two equal groups. Group A patients underwent microsurgical sub-inguinal varicocelectomy and Group B patients underwent conventional/open sub-inguinal varicocelectomy. Semen analysis was done before surgery and after four months of surgery and 50% improvement in semen parameters were noted. Results: The mean age was 31.69±5.49 years. In group A and group-B ≥50% improvement was observed in 36 (48%) and 21 (28%) respectively. The improvement was significantly higher in group A than group B (p>0.012). Conclusion: The improvement in sperm count and motility was significantly higher in patients treated with microsurgical sub-inguinal varicocelectomy when treated with conventional/open sub-inguinal varicocelectomy. Keywords: Male infertility, Varicocele, Varicocelectomy, Seminal parameters, Microsurgical sub-inguinal, Conventional/open sub-inguinal

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