scholarly journals UNDERSTANDING THE RELATION BETWEEN MANSIK BHAVAS AND VYADHI UTPATTI W.S.R. IMMUNITY

2020 ◽  
Vol 8 (9) ◽  
pp. 4461-4466
Author(s):  
Hemant Kumar ◽  
Rajesh Kumar Sharma ◽  
Dinesh Chandra Sharma
Keyword(s):  
Immune Response ◽  
Review Article ◽  
Point Of View ◽  
The Body ◽  
Pathogenic Microorganism ◽  
Related System ◽  
Precipitating Factor

Whenever there for time of crisis in pandemic (like corona in present time), indication to ‘do not panic’ are always given to society. Why?. Is there any relation of doing panic and getting the disease? Is there any possibility of Mansik Bhavas like anger (Krodha), grief (Shoka), anxiety (Chinta), fear (Bhaya) can be the cause or precipitating factor of infection to any person? Both Ayurveda and modern point of view agrees to the statement that different Mansik Bhavas like Chinta, Shoka, Kama, Krodh, etc. can lead to or can act as Hetu for any disease and hence there is existence of relation between these Mansik Bhavas and Sharirik Vyadhi Utpatti. Immunity is a condition of being able to resist a particular disease especially through preventing develop-ment of a pathogenic microorganism or by counteracting the effects of its products1. It means that whenev-er any disease occurs there must be some loss of immunity in the related system and the factors responsible for the disease are the cause for lowering the immune response which ultimately indicates the effect of dif-ferent psychological behaviors on immunity of the body. Ayurvedic texts are full of examples where Mansik Bhavas are mentioned as Hetu in many diseases. Acharya Charak mentioned in Vimanasthan chapter 6 that there is a relation between Sharirik and Mansik Doshas. In this review article we will understand the Role of Mansik Bhavas in Sharirik Vyadhi Utpatti with differ-ent reference given in Ayurvedic texts and what can be the probable cause of that in terms of immunity ac-cording to modern researches.

scholarly journals The Role of Th17 Response in COVID-19

Cells ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 1550
Author(s):  
Diana Martonik ◽  
Anna Parfieniuk-Kowerda ◽  
Magdalena Rogalska ◽  
Robert Flisiak
Keyword(s):  
Immune Response ◽  
Treg Cells ◽  
The Body ◽  
System Response ◽  
Th17 Response ◽  
Monocyte Chemoattractant Protein 1 ◽  
Acute Infectious Disease ◽  
Cytokine Cascade ◽  
Necrosis Factor

COVID-19 is an acute infectious disease of the respiratory system caused by infection with the SARS-CoV-2 virus (Severe Acute Respiratory Syndrome Coronavirus 2). Transmission of SARS-CoV-2 infections occurs through droplets and contaminated objects. A rapid and well-coordinated immune system response is the first line of defense in a viral infection. However, a disturbed and over-activated immune response may be counterproductive, causing damage to the body. Severely ill patients hospitalised with COVID-19 exhibit increased levels of many cytokines, including Interleukin (IL)-1β, IL-2, IL-6, IL-7, IL-8, IL-10, IL-17, granulocyte colony stimulating factor (G-CSF), monocyte chemoattractant protein 1 (MCP-1) and tumor necrosis factor (TNF). Increasing evidence suggests that Th17 cells play an important role in the pathogenesis of COVID-19, not only by activating cytokine cascade but also by inducing Th2 responses, inhibiting Th1 differentiation and suppressing Treg cells. This review focuses on a Th17 pathway in the course of the immune response in COVID-19, and explores plausible targets for therapeutic intervention.

scholarly journals HYPERMNESIA EUPHORIA OR ANY OTHER DESIRABLE FROM THE POINT OF VIEW OF THE CONSUMER, A PSYCHOTROPIC EFFECT - FIRST AND LEADING ELEMENT IN THE OCCURRENCE AND PRESERVATION OF THE BODY’S DEPENDENCE ON PSYCHOACTIVE FACTORS

2017 ◽  
Vol 9 (3) ◽  
pp. 40-46
Author(s):  
D G Baitubayev ◽  
M D Baitubayeva
Keyword(s):  
Substance Dependence ◽  
Point Of View ◽  
The Body ◽  
Long Term Memory ◽  
Vegetative Nervous System ◽  
Term Memory ◽  
Psychotropic Effect

The work shows the role of the vegetative nervous system (VNS) in the functioning of long-term memory, identity mechanisms of long-term memory in the human evolutionary adaptation and substance dependence. It is shown that, depending on the substance of the body are states like pro- gressive adaptation, that the bodycondition, depending on the chemical and psychogenic psychoactive- factors state of the same circle. It proposed the creation of a branch of medicine that combines study of the dependence of the organism, both on the chemical and psychoactive psychogenic factors. Given the classification of psychoactive factors.Onomastics formulated definitions of terminology changes and additions to be used in a new branch of medicine. Proposed allocation of the International Classifica- tion of diseases separate chapter for the classification of states like progressive adaptation of the body depending on psychoactive factors.

scholarly journals PERAN ORANG TUA TERHADAP PENDIDIKAN ANAK USIA DINI DALAM PANDANGAN ISLAM

Perspektif ◽  
2019 ◽  
Vol 10 (2) ◽  
pp. 58-66
Author(s):  
Denny Erica ◽  
Haryanto Haryanto ◽  
Mari Rahmawati ◽  
Irwin Ananta Vidada
Keyword(s):  
Early Childhood ◽  
Early Childhood Education ◽  
Growth And Development ◽  
Point Of View ◽  
The Body ◽  
Religious Values ◽  
Childhood Education ◽  
State Of Nature ◽  
Role Of Parents

From an Islamic point of view, children are a mandate given by Allah to their parents, to provide good and healthy education, involving families is a place for children to learn, communicate, communicate, and behave towards the environment associated with it, and a children will always need a lot of attention and affection from both parents. The role of parents in the development of early childhood education from an Islamic point of view must be able to provide an explanation of all the children born in a state of nature, instill monotheism and aqeedah truly to children, teach children to help prayer, teach children to read the Koran, motivate children to always pray, teach children to always be grateful, motivate children to worship at the mosque, teach children to always be naked, teach children to always maintain the cleanliness of the body, and teach children to love each other God's creatures. By involving parents in providing education that contains Islamic religious values, it is expected that these early childhood children can support the process of adaptation to the outside environment, bearing in mind that these early childhood have strong character and faith in the process of development of growth and development for child.

scholarly journals IMMUNE MECHANISMS FOR DEVELOPMENT OF CONTROLLED AND PARTIALLY CONTROLLED ASTHMA

2019 ◽  
Vol 21 (3) ◽  
pp. 495-502 ◽  
Author(s):  
T. I. Vitkina ◽  
T. P. Novgorodtseva ◽  
E. P. Kalinina ◽  
E. G. Lobanova ◽  
M. V. Antonyuk
Keyword(s):  
Immune Response ◽  
Management Strategies ◽  
Objective Evaluation ◽  
The Body ◽  
Immune Mechanisms ◽  
Persistent Inflammation ◽  
Th17 Lymphocytes ◽  
Group I ◽  
Asthma Patients

Despite a significant amount of works specifying immune mechanisms of bronchial asthma (BA), different phenotypes observed in this pathology need to be studied. The aim of present study was to analyze functional activity of Th1, Th2 и Th17 lymphocytes, and to determine features of inflammation in controlled and partly controlled asthma.We examined eighty-four BA patients that were divided into 2 groups, depending on the control of symptoms and the clinical course of BA. Group I included 45 patients with controlled BA, whereas group II included 39 patients with partially controlled asthma. The subsets of Th1, Th2, and Th17 lymphocytes were assessed by serum cytokine levels (TNFα, IFNγ, IL-2, IL-4, IL-6, IL-10, IL-17A) using flow cytometry technique.The results of this study were as follows: we have shown a combined T-helper (Th) immune response in asthma patients, with its origin depending on the degree of the disease control. Th2 (62%), Th1/Th2 (20%) and Th1 (18%) types of immune response have been detected in the patients with controlled BA. Th2/Th17 (49%), Th1/Th17 (13%) and Th17 (37%) types of immune response have been identified in the patients with partially controlled BA. It has been shown, that Th1 immune response in patients with controlled asthma is induced by intracellular infection. The formation of the Th1/Th2 phenotype is associated with a site of chronic bacterial infection revealed, and with persistence of viral infection in the body. This phenotype can be used as an indicator of asthma worsening. Further studies in the role of prevalent immune response type in the development of partially controlled BA have shown that activation of Th17 lymphocytes is associated with prolonged course of the disease. Irrespectively of initial phenotype, the development of Th17-dependent immune response seems to result from a durable systemic persistent inflammation.The views on the key role of Th1/Th2 balance in the development of asthma are accomplished by evidence of Th17 lymphocyte involvement into the process, and Th1/Th17, Th2/Th17 phenotypes seem to be the polar features of the disease. Estimation of intensity and phenotype of inflammation in BA will permit a more objective evaluation of the therapy applied, and to choose further management strategies.

scholarly journals Body, Possibility and Biographical Interpretation

2012 ◽  
Vol 8 (3) ◽  
pp. 64-87
Author(s):  
Anabela Pereira
Keyword(s):  
Point Of View ◽  
The Body ◽  
The Other ◽  
Discursive Construction ◽  
Visual Interpretation ◽  
Individual Interaction ◽  
The One ◽  
The Individual ◽  
World Perspective

The aim of this article is to demonstrate how body-representations offer an opportunity for its visual interpretation from a biographical point of view, enhancing, on the one hand, the image’s own narrative dynamics, and, on the other, the role of the body as a place of incorporation of experiences, as well as, a vehicle mediating the individual interaction with the world. Perspective founded in the works of the artists Helena Almeida and Jorge Molder, who use self-representation as an expression of these incorporated (lived) experiences, constitutes an important discursive construction and structuring of their narrative identity through visual creation, the artists enable the other with moments of sharing knowledge, creativity and subjectivity, contributing also to the construction of the contemporary, cultural and social imagery.

scholarly journals Bodies and persons: The politics of embodied encounters in asylum seeking

2020 ◽  
pp. 030913252093844
Author(s):  
Jouni Häkli ◽  
Kirsi Pauliina Kallio
Keyword(s):  
Power Relations ◽  
Point Of View ◽  
The Body ◽  
The Political ◽  
Theoretical Understanding ◽  
Political Struggles ◽  
Original Thinking ◽  
Sense Of Power

In this paper, we propose that there is a politics of encounters centered on the body at play in seeking asylum and refuge, and that it is critical to study how it unfolds from the point of view of both governing and agency. Building on existing work that looks at the role of embodiment in the political struggles of refugees, and leaning on Helmuth Plessner’s original thinking about social embodiment, we develop a theoretical understanding of this political dynamic, illustrating how it can help us make sense of power relations and forms of governance and (latent) resistance involved in it.

Immune response in HIV epidemics for distinct transmission rates and for saturated CTL response

2019 ◽  
Vol 14 (3) ◽  
pp. 307 ◽  
Author(s):  
Ana R.M. Carvalho ◽  
Carla M.A. Pinto
Keyword(s):  
Immune Response ◽  
Disease Transmission ◽  
Cytotoxic T Lymphocyte ◽  
Point Of View ◽  
Ctl Response ◽  
Transmission Rates ◽  
Distinct Disease ◽  
The Stability ◽  
Disease Free

In this paper, we study the immune response in a fractional order model for HIV dynamics, for distinct disease transmission rates and saturated cytotoxic T-lymphocyte (CTL) response. Our goal is twofold: (i) to analyze the role of the order of the fractional derivative, α, on the efficacy of the immune response, (ii) to examine the immune response for distinct transmission functions, in the presence of saturated CTL response. We compute the reproduction number of the model and state the stability of the disease-free equilibrium. We discuss the results of the model from an epidemiological point of view.

COVID-19: WHAT PEDIATRICIANS LEARNED ABOUT PECULIARITIES OF THE IMMUNE RESPONSE TO A NEW CORONAVIRUS INFECTION AFTER YEAR OF FIGHTING IT

2020 ◽  
Vol 99 (6) ◽  
pp. 32-51
Author(s):  
L.S. Namazova-Baranova ◽  
◽  
A.A. Baranov ◽  
◽  
Keyword(s):  
Immune Response ◽  
Age Groups ◽  
Point Of View ◽  
The Body ◽  
Medical Community ◽  
Case Scenario ◽  
Worst Case ◽  
The World ◽  
Coronavirus Infection ◽  
The Impact

A year ago, the world heard about an outbreak of a new severe coronavirus infection in China, which later, after its rapid spread across the globe, WHO defined as a pandemic. Pediatricians, of course, expected the worst-case scenario and mass illness of the most vulnerable patients – children and people of older age groups with a new infectious disease. From the immunological point of view, everything is obvious – the new pathogen is most dangerous for those who have not yet formed a defense against it, or for those with weakened defense. But it quickly became clear that, unlike, for example, a flu pandemic, there is an unexpected situation when adults, including elderly and senile patients, become seriously ill and die, and children remain practically outside the spread of the infectious process. During a year of living «in a new reality», not only physicians, but all of humanity learned to respond to a new infectious challenge, empirically looking for possible therapeutic or diagnostic interventions and at the same time trying to plan and implement scientific research that would help shed light on the questions posed. For the first time, the international medical community united to perform serious clinical trials of drugs that were proposed for the treatment or prevention of COVID-19. As a result of actions of scientists and clinicians around the world, answers to some questions were obtained, however, most of the information on the impact of the new coronavirus on the human body, including children, is still unavailable to medical practitioners. The review presents latest data on the causative agent of the new coronavirus infection, its effect on the body of children and adults, describes peculiarities of immune response to the new virus, and outlines basic principles of managing such patients in real clinical practice.

Role of autopsy in COVID-19 patients

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1517-1523
Author(s):  
Vriti Pursnani ◽  
Amit Reche ◽  
Gaurav Majumdar ◽  
Prerna Gautam ◽  
Kumar Gaurav Chhabra ◽  
...  
Keyword(s):  
Respiratory System ◽  
Review Article ◽  
The Body ◽  
Personal Hygiene ◽  
Treatment Modalities ◽  
Shortness Of Breath ◽  
Human Waste ◽  
Entire Country ◽  
Indian Scenario

Coronavirus disease 2019 had caused a pandemic leading to over 6M positive cases worldwide out of which 3.73 lac are demised (until when the article was written). Its first outbreak was seen in Wuhan, China. In the Indian scenario, we have a total of 2 lac cases out of which 5,679 have been deceased (until when the article was written). Due to the high transmissibility of this disease, the entire country is under lockdown to prevent the spread of the virus. The main etiology of this virus is the severe acute respiratory syndrome coronavirus-2(SARS-CoV-2). This affects the respiratory system leading to cough, shortness of breath, and fever. There have been cases with mild or no symptoms reported, but the cause of death is due to the virus. This helps us understand the diagnosis, epidemiology, symptoms, and pathophysiology about the virus, which can help in treatment modalities. An autopsy is one of the methods by which we can understand the systematic involvement other than the respiratory system. Various pathological, microbiological changes can occur in the other organs. Even though the person is deceased, the virus is highly infectious can cause the spread through body fluids. Proper care must be taken while handling the body and performing the procedure. This review article aims to focus on the autopsy findings found in various cases to study the disease pathophysiology of the SARS-CoV-2. This article also helps us understand the guidelines that have been put forward by WHO and CDC must be followed regarding the specification required in the autopsy room; PPE’s to be worn, human waste and fluid disposal, body transportation. Proper personal hygiene must be maintained while handling the COVID-19 patients; this can lead to less susceptibility of acquiring the disease.

3. Kill or be killed

2018 ◽  
pp. 24-32
Author(s):  
Dorothy H. Crawford
Keyword(s):  
Immune Response ◽  
Herpes Simplex ◽  
The Body ◽  
Protective Mechanism ◽  
Human Immune Response ◽  
Human Immune ◽  
Epstein Barr ◽  
Living Organisms ◽  
Simplex Virus

‘Kill or be killed’ shows how viruses survive—they must reproduce before the host either dies or its immune system recognizes and eliminates them. The transmission routes of viruses such as flu, measles, common cold, herpes simplex virus, HIV, Epstein–Barr, and hepatitis B are discussed. How do we fight viruses? All living organisms have defences against invading viruses. Vertebrates, and possibly some invertebrates, are immune to re-infection by the same virus. Another protective mechanism, used by plants, but also by insects and other animal species, is gene silencing by RNA interference. The human immune response is explained, discussing the role of lymphocytes and immunopathology, where the immune response may actually harm the body.

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