scholarly journals EFFICACY OF SOME INDIGENOUS HERBS ON YUVANAPIDIKA W.S.R. TO ACNE VULGARIS: A REVIEW

2021 ◽  
Vol 9 (4) ◽  
pp. 838-842
Author(s):  
Lekshmy M ◽  
Shuchi Mitra ◽  
Yadevendra Yadav ◽  
Khem Chand Sharma
Keyword(s):  
Herbal Remedy ◽  
Human Life ◽  
Acne Vulgaris ◽  
Psychological Impact ◽  
Modern Medicine ◽  
Chronic Inflammatory Disease ◽  
Herbal Drugs ◽  
Prevalent Disease ◽  
Common Skin ◽  
Microbial Agents

Acne vulgaris is a chronic inflammatory disease mainly affecting the teenagers. As it is chronic and affects face mainly, it always causes negative psychological impact on human life. In a study conducted in 2015 acne affected 650 million people globally making it the most common skin disease worldwide. In a study of “Global burden of disease” it is revealed that acne was the 8th common prevalent disease worldwide. In Ayurveda the features of Mukhadusika or Yuvanapidika can be correlated with Acne vulgaris. In modern medicine anti-biotics are mainly used for the treatment of acne. Due to increasing resistance of anti-microbial agents, side effects, and sometimes high cost of treatment, it is necessary to find herbal remedy for the cure of acne. In this article a review of efficacy of 5 potential herbal drugs for acne is done. These herbal drugs are Manjishta, Shalmali, Ghrit kumari, Daruharidra, and Yashtimadhu. Keywords: Yuvanapidika, Mukhadushika, Manjistha, Shalmali, Daruharidra, Ghritakumari, Yasthimadhu

scholarly journals Clinical profile of acne vulgaris in semiurban patients

2018 ◽  
Vol 4 (1) ◽  
pp. 23
Author(s):  
Kshitij Saxena ◽  
Yogesh M. Shah ◽  
K. K. Singh ◽  
Shobhit Dutt ◽  
Meenal Agrawal ◽  
...  
Keyword(s):  
Age Of Onset ◽  
Acne Vulgaris ◽  
Chronic Inflammatory Disease ◽  
Clinical Profile ◽  
Acne Lesion ◽  
Dermatology Clinic ◽  
Common Skin ◽  
Associated Conditions ◽  
Acne Scarring ◽  
Grade 3

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Acne is a chronic inflammatory disease of the pilosebaceous unit, mainly affecting face and frequently followed by scarring. It is the most common skin disease in an urban dermatology clinic in India. Adult acne is more common in women and may be a marker of hyperandrogenism.The present study was carried out to study the clinical profile of acne vulgaris in semiurban patients.</span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">The study was conducted for 1 year on all eligible patients of acne vulgaris attending dermatology OPD of a hospital catering to semiurban patients. Data including grade of acne, markers of androgenicity and post-acne scarring was collected. Statistical analysis was done using SPSS 15 software</span>.<strong></strong></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Frequency of acne vulgaris patients in the dermatology OPD was 2.8% with 429 acne patients out of 15,322 new patients. Female to male ratio was 1.44:1. The mean age of onset in males was 16.24 and in females, 14.84 years. Grade 2 acne (66%) was commonest followed by grade 3 (5.1%) and grade 4 (3.7%). Associated conditions seen were seborrhea (60.8%), alopecia (18.9%), acanthosis (4.9%) and PCOD (2.3%). Markers of androgenicity were more frequently seen in grade 2 acne which was statistically significant. Atrophic scars were commonest including icepick scars (80.2%), rolling scars (67.4%) and box scars (57.8%). </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">In our study females had an earlier onset and closed comedones were the most common acne lesion. Grade 2 acne vulgaris formed majority of patients. Grade 4 acne vulgaris was more common in males.</span></p>

scholarly journals Pharmacokinetic study of rational regimen of oral clindamycin in comparison with doxycycline in mild cases of acne vulgaris

2017 ◽  
Vol 6 (11) ◽  
pp. 2616
Author(s):  
N. Arivazhagan ◽  
R. Saravana Kumar ◽  
R. Arbind Kumar
Keyword(s):  
Low Dose ◽  
Acne Vulgaris ◽  
Tertiary Care ◽  
Chronic Inflammatory Disease ◽  
Causative Organism ◽  
Age Group ◽  
Propionibacterium Acne ◽  
Common Skin ◽  
Dose Oral

Background: Acne vulgaris is a chronic inflammatory disease of pilosebaceous units. It is a common skin disorder affecting both boys and girls in the adolescent age group and also extends into the post adolescent age group. From time immemorial, various remedies have been suggested and followed by Ayurvedic, Siddha, Unani practitioners and native healers present in various parts of the world. In this study an attempt has been made to evaluate the efficacy of a low dose oral Clindamycin in Acne vulgaris and the results of the study have been presented in ensuing chapters.Methods: The Prospective, Randomized Controlled, Single blind study was conducted in Out Patient Section, Department of Dermatology, tertiary care teaching hospital September 2016 to May 2017 for Total six weeks. Drug administration - four weeks. Follow up - two weeks mostly drug used Capsule Clindamycin 50mg. Capsule Doxycycline 100 mg. Benzoyl Peroxide 5% topical cream.Results: The objective of the study is not only to find out the efficacy of a low dose of 50 mg Clindamycin given orally, but also to find out if this efficacy is obtained without producing the adverse effects for which the administration of Clindamycin is hesitated the ant-microbial, Cap. Doxycycline and Cap. Clindamycin act in acne vulgaris by their effect on the Propionibacterium acne. These antibiotics decrease the population of Propionibacterium acne which in turn leads to the inhibition of the bacterial lipases and this is followed by a decrease in concentration of free fatty acids. This produces less tissue inflammation and acne.Conclusions: This study proves the safety and efficacy of low dose of oral Clindamycin in acne vulgaris, and such low doses can also be tried for other infections where the causative organism responds to Clindamycin. 

Dermatology in primary care: an audit of the proportion of patients who present to general practice with a dermatological problem that could be self-managed

2020 ◽  
Vol 70 (suppl 1) ◽  
pp. bjgp20X711053
Author(s):  
Luamar Dolfini ◽  
Yogesh Patel
Keyword(s):  
Primary Care ◽  
General Practice ◽  
Acne Vulgaris ◽  
Clinical Information ◽  
Electronic Record ◽  
Self Management ◽  
Considerable Proportion ◽  
Dry Skin ◽  
Record System ◽  
Common Skin

BackgroundA considerable proportion of GPs’ workload is dermatological. It is important to investigate what common skin conditions encountered in primary care can be self-managed, in an effort to alleviate the burden on primary care.AimThe purpose of the audit was to identify the proportion of consultations that are dermatological in nature and analyse potential for self-management by patients.MethodData was collected using the patient electronic record system (EMIS) in general practice. A search was made for all consultations from the 17 April to 15 May 2019, which included all new presenting complaints that were dermatological in nature. The criteria for self-management included advising over the counter (OTC) medication or reassurance. On the other hand, a case was deemed not self-manageable if prescription only medication (POM) was prescribed or if a referral to dermatology was made.ResultsThere were a total of 2175 consultations, where 246 (11.31%) cases were dermatological. Of the 246, 80 cases (32.5%) could be self-managed. There were 46 different dermatological presenting complaints of which the 5 most common included: rash (51 cases), dermatitis (44 cases), acne vulgaris (13 cases), moles (12 cases), dry skin (11 cases). None of the acne or moles cases could be self-managed, whereas 23%, 68.2%, 72.7% of rashes, dermatitis, and dry skin cases, respectively, could be self-managed.ConclusionCertain dermatological conditions have more potential for self-management than others. Research into teledermatology as a means of addressing patient concern and providing clinical information is important in order to reduce unnecessary consultations.

A Critical Review on Tamaka Shwasa (Bronchial Asthma) - An Ayurvedic View

2017 ◽  
Vol 2 (3) ◽  
Author(s):  
Sandip R. Baheti ◽  
Deepa Sharma ◽  
Saroj Devi ◽  
Amit Rai
Keyword(s):  
Bronchial Asthma ◽  
Inflammatory Disease ◽  
Critical Review ◽  
Modern Science ◽  
Modern Medicine ◽  
Chronic Inflammatory Disease ◽  
The Body ◽  
Natural Immunity ◽  
Shortness Of Breath ◽  
Asthma Symptoms

Difficulty in breathing or shortness of breath may be simply termed as Shwasa (Asthma), As per Ayurveda, Shwasa is mainly caused by the Vata and Kapha Doshas. Shwasa is broadly classified into five types in Maha Shwasa (Dyspnoea major), Urdhawa Shwasa (Expiratory Dyspnoea), Chinna Shwasa (Chyne-stroke respiration), Kshudra Shwasa (Dyspnoea minor), Tamaka Shwasa (Bronchial Asthma). In modern science Tamaka Shwasa can be correlated with Asthma, Asthma which is a chronic inflammatory disease of airway. In modern medicine there is no cure for Asthma, symptoms can typically be improved. In Ayurveda, Asthma can be effectively and safely manage the condition without inducing any drug dependency where Pachakarma procedures and use of internal medication detoxifies the body, provides nutrition and increases the elasticity of lung tissue it also develops natural immunity of the body thus decreasing episodic recurrence of the disease.

Sidharthakadi Lepa in Mukhadushika - A Clinical Study

2018 ◽  
Vol 3 (01) ◽  
Author(s):  
Ravindra Angadi ◽  
Rekha J.
Keyword(s):  
Skin Disorder ◽  
Acne Vulgaris ◽  
Response To Therapy ◽  
Inclusion Criteria ◽  
Pilosebaceous Unit ◽  
External Application ◽  
Acne Lesion ◽  
Common Skin ◽  
The Face ◽  
Inflammatory Component

Background: Acne vulgaris is a very common malady of adolescents. It is common enough to be called as a physiological process but is better regarded as a disease due to its inflammatory component and the disfigurement. Acne vulgaris is a common skin disorder of pilosebaceous unit that primarily affects the face which if not treated leads to pigmentation. Mukhadushika is a Kshudra Roga which mainly involves Kapha and Vatadosa with Raktha. This is a common illness affecting 80 % of adolescents. Lepa is one of the external therapies explained in Ayurvedic classics. Objectives: To evaluate the efficacy of Sidharthakadilepa in the management of mukhadushikaw.s.r. to acne vulgaris. Methods: 30 patients fulfilling the inclusion criteria were selected. They were given Sidharthakadi Lepa for external application over face for one month. Patients were observed for changes on 7th, 14th, 21st and 28th day. The response to therapy was evaluated at the end of 28 days by calculating acne lesion score and the efficacy was determined by the percentage reduction in ALS. Results: The analysis revealed that 40% of patients had complete remission, 30% patients showed marked improvement and 30% showed moderate improvement.

scholarly journals Water Quality and Life Expectancy: Parallel Courses in Time

Water ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 752
Author(s):  
Andreas N. Angelakis ◽  
Heikki S. Vuorinen ◽  
Christos Nikolaidis ◽  
Petri S. Juuti ◽  
Tapio S. Katko ◽  
...  
Keyword(s):  
Water Quality ◽  
Life Expectancy ◽  
Human Life ◽  
Life Quality ◽  
Modern Medicine ◽  
Personal Hygiene ◽  
Water Supply Systems ◽  
Improved Sanitation ◽  
Ancient Times ◽  
Concomitant Factors

Since ancient times, the need for healthy water has resulted in the development of various kinds of water supply systems. From early history, civilizations have developed water purification devices and treatment methods. The necessity for fresh water has influenced individual lives as well as communities and societies. During the last two hundred years, intensive and effective efforts have been made internationally for sufficient water quantity and quality. At the same time, human life expectancy has increased all over the globe at unprecedented rates. The present work represents an effort to sketch out how water purity and life expectancy have entangled, thus influencing one another. Water properties and characteristics have directly affected life quality and longevity. The dramatic increase in life expectancy has been, indisputably, affected by the improvement in water quality, but also in other concomitant factors, varying temporally and spatially in different parts of the world throughout the centuries. Water technologies and engineering have an unequivocal role on life expectancy. In some cases, they appear to have taken place earlier than the progress of modern medicine. Among these, improved sanitation, personal hygiene, progress in medicine, and better standards of economic living have played the greatest roles.

scholarly journals Treatment of acne and acne-related scarring with fixed combination clindamycin phosphate and benzoyl peroxide gel (1.2%/3.75%) and tretinoin gel microsphere 0.06% in an Asian American transgender female

2020 ◽  
Vol 8 ◽  
pp. 2050313X2098403
Author(s):  
Edidiong CN Kaminska
Keyword(s):  
Benzoyl Peroxide ◽  
Asian American ◽  
Skin Diseases ◽  
Fixed Combination ◽  
Acne Vulgaris ◽  
Topical Therapy ◽  
The United States ◽  
Clindamycin Phosphate ◽  
Common Skin ◽  
Group Post

Acne vulgaris is one of the most common skin diseases in the United States and can affect any gender or ethnic group. Post-inflammatory hyperpigmentation (PIH) and scarring from acne can have a negative psychosocial impact on patients. Skin of color patients are particularly prone to PIH, as the dark marks left from acne may take several months to resolve, far after the acne has cleared. Here, we report a case of moderate acne with associated scarring in a transgender, Asian American female who was successfully treated with fixed combination topical therapy with clindamycin phosphate and benzoyl peroxide gel 1.2%/3.75% and tretinoin gel microsphere 0.06%.

Positive And Negative Aspects Of The Psychological Impact Of The Virtual World

2021 ◽  
Vol 03 (05) ◽  
pp. 25-29
Author(s):  
Rakhimova I.I. ◽  
◽  
Mukhiddinova U.A. ◽  
Bеrdiqulоvа G.N. ◽  
Suleymanova D.I. ◽  
...  
Keyword(s):  
Mobile Phones ◽  
Virtual World ◽  
Human Life ◽  
Psychological Impact ◽  
Economic Life ◽  
The Internet ◽  
National Values ◽  
Use Of The Internet ◽  
The Individual

In today's age of the Internet, computers and mobile phones for people of all ages are available in almost every home. In addition, in today’s world-wide pandemic, the use of the Internet for education and all aspects of cultural, socio-economic life as well as games such as games is growing rapidly. This, in turn, has a psychological effect on the individual, both positively and negatively on our society and national values. In this article, I have tried to highlight the positive and negative aspects of the internet world that affect the individual. In the article we will focus on the role of the virtual world in human life, the need not to depend on it, to use it for useful purposes.

scholarly journals Ten Famous Composers of the Romantic Era and their Cause of Death

2021 ◽  
Author(s):  
Ernest K.J. Pauwels
Keyword(s):  
Medical Research ◽  
Cause Of Death ◽  
21St Century ◽  
Causes Of Death ◽  
Human Life ◽  
Modern Medicine ◽  
Expression Of Emotion ◽  
The World ◽  
Romantic Era ◽  
Clinically Significant

The musical composers in the Romantic Era (1800-1910) strived for compositions that expressed human life, including happiness, harmony and despair. They lived in a period in which freedom of thinking, expression of emotion and inspiration by nature predominate. During this period, intensive trading with other parts of the world brought new microorganisms along, which made infections and epidemics very common. This article serves to address the cause of death and relevant biographic data of a number of well- known Romantic composers. Primarily, this review refers to clinically significant findings using reports that were retrieved from Pubmed, Embase and Google over the 19th, 20th and 21st century till 14th June 2021. Here, this text dwells on diseases and the cause of death of ten composers, namely Mozart, Beethoven, Chopin, Schubert, Schumann, Mendelssohn, Brahms, Liszt, Mahler and Bruckner. It is evident that, in the sight of modern medicine, symptoms and forensic facts are not complete, but witnesses' reports and recent medical research have provided passable and plausible clarity. Although many questions will remain unanswered, it appears that the diseases of these composers and their causes of death have their origins in alcohol abuses, age, epidemics (like tuberculosis) and syphilis.

scholarly journals Contamination of Asian herbal drugs : Need for its critical evaluation

2009 ◽  
Vol 1 (2) ◽  
pp. 291-297 ◽  
Author(s):  
K.K. Gupta ◽  
G. Prasad ◽  
A.K. Chopra ◽  
D.R. Khanna
Keyword(s):  
Large Scale ◽  
Human Life ◽  
Medical Science ◽  
Critical Evaluation ◽  
Chemical Components ◽  
Severe Adverse Effect ◽  
World Population ◽  
Herbal Drugs ◽  
Human Pathogens ◽  
Dual Action

Herbal drugs have been used as remedies for the treatment of large number of humans, ailments since ancient times as the traditional medicine system; India has a glorious past, having first documented record of fully developed medical science known as Ayurveda written by several ancient Rishi’s. Major groups of indigenous system of medicine are based on herbal drugs. A survey made by WHO indicated that about 80% of the world population relies on herbal drugs. Herbal drugs are becoming more popularized and important even in the developednations with hope of their non-toxicity and may play a role of substitute to overcome the problems of multi drug resistant pathogens. Cultivation of drug plants has been started in large scale without considering the land quality and in certain cases irrigation with waste water. Application of different fungicides, pesticides in that specific field or in neighboring fields may be directly deposited superficially or may be absorbed by the plant system. Therefore in the present situation possibilities of the Asian herbal drugs, contaminated with large number of toxic components cannot be ignored which may severely hurt human life in place of healing or curing.These contaminants may be either alone or in combination and may be originated intrinsically, extrinsically and deliberately. Certain contaminants may be highly toxic and may cause severe adverse effect in the human system. Some of the important contaminants are the heavy metals like lead, arsenic, cadmium, mercury, copper and pesticides. Adulteration of modern drugs to enhance drug potency and heterogenous microbial population including human pathogens may contaminate both raw and powdered herbal drugs. Among these contaminants, microbial contamination seems more severe and may be due to their dual action on the drug i.e. utilization of medicinally important chemical components as nutrients and in certain cases by producing certain mycotoxins, which may be even carcinogenic under certain conditions . Critical evaluation of both raw and powdered herbal drugs for contaminants is the urgent need of the time in order to provide safety measures in herbal health care medicine.

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