scholarly journals A COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFICACY OF KANJIKADI GHRITA AND AMRUTADI GHRITA SNEHAPANA FOR VIRECHANA IN AMAVATA WITH SPECIAL REFERENCE TO RHEUMATOID ARTHRITIS

2021 ◽  
Vol 9 (11) ◽  
pp. 2698-2706
Author(s):  
Kavya J H ◽  
Rajesh Sugur ◽  
Doddabasayya Doddabasayya

Amavata is a Vata and Kapha Pradhana Vyadhi caused due to Viruddha Ahara and Vihara resulting in Mandagni, leading to the formation of Ama. Ama with the influence of Vata Dosha circulates all over the body and gets lodged in Shleshma Sthana in Sandhi Pradesha, resulting in the manifestation of Amavata. Snehapana is a mandatory Poorvakarma before Shodhana. Snehapana does the Uthklesha of Doshas before Shodhana, without which proper achievement of Shuddhi is not possible. Snehapana and Virechana are the main lines of treatment for Amavata. To evaluate the better result, here for Snehapana Kanjakadi Ghrita & Amruthadi Ghrita were taken before Virechana which is then compared and analysed statistically. A minimum of 40 patients, fulfilling the diagnostic and inclusion criteria of Amavata according to Ayurveda classics and based on criteria fixed by the American Rheumatology Association (ARA) in 1988 criteria will be selected and randomly assigned into 2 groups, i.e. Group A and Group B consisting minimum of 20 patients in each group. Comparative analysis of the overall effect of the treatments in both groups was done statistically with the Unpaired T-Test. The test shows that the treatment is statistically not significant in Group A when compared to Group B. Overall result of Group A is 25.08% and the overall result of Group B is 31.07%. Keywords: Amavata, Kanjikadi Ghrita, Amritadi Ghrita, Snehapana, Virechana

Author(s):  
Maumita Halder ◽  
Prashant V Kulkarni ◽  
Abhijit Shinde ◽  
Binu.M.B

Amlapitta may be a clinical entity manifesting within the Annavaha Srotas. Kashyapa and Madhava have described this disease thoroughly. Amlapitta has become quite common because of the change within the food and life styles, sophistication and a stressful life. It is characterized by Avipaka, Klama, Tiktodhgara, Amlodhgara, Gaurava, Hritkanthadaha and Aruchi indicating the Vikruthi of Pachakapitta, Kledakakapha and Samanavata. The etiological factors and therefore the symptomatology manifested relate Amlapitta to diseases mentioned under Acid Peptic Disorders. Nistushayadi Kwatha and Phalatrikadi kwatha were selected. The main objectives of the study are to study and compare the effect of Nistushayadi Kwatha and effect of Phalatrikadi kwatha in the management of Amlapitta. A total of 40 patients who fulfilled the inclusion criteria were selected, and randomly assigned into two groups i.e., Group A and Group B, comprising of 20 patients each. Group A and Group B were administered Nistushayadi kwatha and Phalatrikadi Kwatha respectively for 30 days. Both the groups were advised Pathya Ahara. They were followed up after every 10th days. After the intervention the Samanya Lakshana of Amlapitta were observed, recorded and assessed. The overall assessment of both the groups, where group A receives Nistushyadi kwatha and group B Phalatrikadi kwatha shows promising improvement in the subjective parameters. Assessment was done using unpaired ‘t’ test between these two groups, the result was not quite statistically significant which means there is no much difference in the efficacy of these two formulation in the management of Amlapitta. Both the formulations shown nearly same outcome in the improvement of disease parameter. The reduction in the symptoms were started to be noticed by 7th day where the patients had reduction in Hrutkantha Daha, Aruchi, Kanthadaha and Angagourav. These symptoms resolved by 30th day.


2020 ◽  
Vol 5 (05) ◽  
pp. 96-103
Author(s):  
Deepa S. Patil ◽  
Prashanth A.S

Rajonivrutti condition manifests in the end phase of Jarawastha; but its Samprapti begins from the Sandhikala of Madhyamawastha and Jarawastha due to Vatavruddi in womens reaching Rajonivrutti. Postmenopausal Asthikshaya is a disabling disease, which renders women a bedridden life. Here 40 subjects diagnosed with postmenopausal Asthikshaya fulfilling the inclusion criteria were selected for the study and randomly categorized intp two groups as group A and group B each consisting of 20 subjects. Group A received Amapachana with Hinguvachadivati, Yastimadhu Siddha Ksheerabasti administered in Yoga Basti schedule followed by Tritiyatriphala Rasayana. Group B received Amapachana with Hinguvachadivati, Sadhyosnehapana with Amrita Ghrita, Sarvanga Abyanga with Murchita Tilataila followed by Sarvanga Swedana and Sneha Virechana was admistered with Eranda Taila followed by Tritiyatriphala Rasayana was given. Tritiya Triphala Rasayana selected for the present study by adapting all the general principles of prevention and management of Asthikshaya and as it is a well known Rasayana.


2020 ◽  
Vol 5 (04) ◽  
pp. 31-36
Author(s):  
Conception Costa ◽  
Sudarshan A. ◽  
Jeejo Chandran O

Background: Apabahuka is a Vataja Nanatmaja Vyadhi, in which locomotive functions of Amsa Sandhi are affected mainly due to Vata Dosha Prakopa causing pain, stiffness and restricted movement of the shoulder. Apabahuka can be correlated to Frozen shoulder or Adhesive Capsulitis in modern medicine because of similar symptomatology. Nasya is indicated in Urdhwajatrugata Vikaras. Pinyaka Taila and Swalpa Masha Taila are Vatahara Taila used for Nasya. Method: A single blind randomised clinical study in which 40 clinically diagnosed patients of Apabahuka, fulfilling the inclusion criteria were selected and divided into two groups - Group A treated with Pinyaka / Panchamula Taila Nasya and Group B treated with Swalpa Masha Taila Nasya, comprising of 20 patients each. Result: Statistically Nasya with Pinyaka Taila showed better results in Pain (51.2%), Stiffness (48%), Tenderness (58.33%), with improvement in goniometric readings of shoulder ROM than Nasya with Swalpa Masha Taila in Pain (39.4%), stiffness (40.9%), Tenderness (58%). Discussion: Rukshadi Gunas of Vata are increased in Apabahuka hence Viparita Gunas like Snigdhadi in the form of Brumhana Nasya with Pinyaka Taila was found to be effective in Apabahuka. In the present study Group A Nasya with Pinyaka Taila showed better effect than Group B Nasya with Swalpa Masha Taila.


2020 ◽  
Vol 5 (05) ◽  
pp. 104-110
Author(s):  
Sharanamma A ◽  
Prashanth A.S. ◽  
S.G. Chavan

Tarunyapiadaka is one of the Kshudraroga and most common skin disorders. Ayurvedic medicine plays important role in the patients who are in deep depression due to disfiguration of face and Tarunyapidaka in the field of Cosmetiology. In the present study an effort has been made to formulate an effective, economic and simple remedy to help in the total cure and preventing of Tarunyapidaka. In the present study 40 Subjects diagnosed with Tarunyapidaka w.s.r to Acne Vulgaris fulfilling the Inclusion criteria were selected for study and randomly categorized into two groups as Group A and Group B each consisting of 20 subjects from OPD and IPD of department of PG studies in Kayachikitsa department of Ayurveda Mahavidhyalaya, Hubbali have been treated with Amapachana with Guduchi Churna. In group A Sadhyosnehapana with Panchatikta Ghrita. Sarvanga Abhyanga with Elaadi Taila followed by Sarvanga Swedana. And Sneha Virechana was administered with Trivruth Lehya. After Samsarjana Krama, Navaka Kashaya given as a Shamanoushadi along with Manjista with Madhu Lepa. In Group B Sadhyosnehapana with Panchatikta Ghrita. Sarvanga Abhyanga with Elaadi Taila followed by Sarvanga Swedana and Sneha Virechana was administered with Trivruth Lehya. After Samsarjana Krama, Gopanganadi Kashaya given as a Shamanoushadi along with Manjista with Madhu Lepa for 45 days to assess the clinical efficacy of Navaka Kashaya and Gopanganadi Kashaya. Significant changes in Subjective and Objective criteria were observed.


Author(s):  
Pankaj Kumar Verma ◽  
Pratap G ◽  
Veeraj Hegde

Sleep is a serious health ailment that affects millions of people. It is one of the most significant human behaviour occupying roughly one third of human life. Sleep occupies a greater portion of our life and is considered as one among the three Upastambhas of existence. Charaka has explained the management of Nidranasha (Insomnia) with both external and internal treatments. Presently people are not getting sufficient hours of sleep because of busy life schedules and overload, as a result of which, work hours have replaced time of sleep. Recent studies have shown that anxiety and stressful environment has created an imbalance in the physiological activity of the body leading to disturbed sleep and other anomalies. A Randomized comparative clinical study of 40 patients suffering with classical signs and symptoms of Anidra (Insomnia) of either sex divided into two groups viz. Group A - (Study group) - Treated with Pippali Moola (Root of Piper Longum) with Guda (Jaggery), Group B - (Placebo Group) - Acacia resin with a study duration of 14 days, including follow-ups. The data during the study was recorded and analyzed statically.


2021 ◽  
Vol 04 (11) ◽  
pp. 53-64
Author(s):  
Lavanya B.C ◽  
Roopa Bhat

A comparative clinical study to evaluate the therapeutic effect of Khadira aristadi Kashayaand Navaka Kashayain the management of Vicharchika. A single blind Controlled comparative clinical study with pre test and post test design. Conducted in DhanvantariAyurveda medical college Hospital; Siddapur, Karnataka.40 patients suffering from Vicharchika/ Dermatitis of either sex were selected for the study.Selected patients were treated under two groups; A and B. Group A with oral administration of Khadira aristadi Kashaya, in a dose of 30 ml before food twice a day with sukhoshna jalaas anupanaand the same is continued for 30 days. Group B with oral administration of Navaka Kashaya, in a dose of 30 ml before food twice a day with sukhoshna jalaas anupanafor 30 days .The response following the intervention was assessed on 1st,15th, 21st, and 30thdays to find out the progress of theCondition in both the groups.Further the change observed by the completion of the treatment was subjected to paired and unpaired t test to know the statistical significance. By using paired t test both the group parameters were statistically highly significant (P<0.001).Mean wise group A shows more improvement than group B.By Using unpaired t test: group A is showing more relief (%) in Pidaka, Kandu, Shyavataand Sravaalso statistically proved. In Kandurelief was statistically highly significant (P<0.001) and Pidakaand Sravastatically significant (P<0.005) in these parameters. Final conclusion of this comparative clinicalstudy is Group A is more effective than Group B (Khadira aristadi Kashayais more effective than Navaka Kashaya) in the management of Vicharchika.


2020 ◽  
Vol p5 (01) ◽  
pp. 2563-2569
Author(s):  
Smita M. Choudari ◽  
Rahul R. Kulkarni ◽  
Prasan V. Joshi

Amlapitta is a disease of Annavaha srotas which is characterized by the symptoms like Avipaka, Klama, Utklesha, Tikta Amlodghara, etc. explained by Acharyas. It is the most disturbing and irritable condition. As the Nidana leading to impairment of Pachakagni causes many diseases like Ajeerna, Aruchi, Agnimandya, Amlapitta etc. Agni is responsible for digestion of food. Amlapitta is Pittapradhana Tridoshaja Vyadhi. Because of the vitiation of Pitta there is Mandagni. Ghrita which is claimed to be Pittashamaka, Dahashamaka and Agnideepaka. So, in the present study the Jeerakadhya Ghrita was taken to treat the Mandagni and vitiated Pittadosha. Jeerakadhya Ghrita, mentioned in Bhaishjya Ratnavali and Chakradatta by the virtue of its Rasa, Guna, Veerya, Vipaka and Samyoga helps in Pitta Shamana, Daha Shamana, Agni Deepana, and Ama Pachana. In the present study, 30 patients diagnosed with Urdhvagha Amlapitta were selected randomly and allocated to Group A and Group B. Group A received Placebo capsule and Group B Jeerakadhya Ghrita. Group A with placebo was studied to compare the efficacy of Jeerakadhya Ghrita was done. Results were analyzed statistically. The study proves that Jeerakadhya Ghrita has a significant effect in Urdhvagha Amlapitta and Non-Digestible Cellulose used as a placebo has no significant effect in Urdhvagha Amlapitta.


AYUSHDHARA ◽  
2020 ◽  
pp. 2882-2894
Author(s):  
Sourabh Gupta ◽  
M.A. Hullur

Amavata is a crippling condition where simultaneously aggravated Vata and Ama associated with each other settles in Sandhis and produce Sandhishoola, Sandhishotha, Sparshaasahitwa, which is similar to Rheumatoid Arthritis. The present study has made an attempt to find an effective Ayurvedic treatment modality through Kshara Vasti and Vaitarana Vasti along with Shamanoushadhi. A total of 30 Patients were randomly divided in two groups with 15 patients in each group. In Group A, Kshara Vasti and in Group B, Vaitarana Vasti was given in Yoga Vasti schedule followed by Shamanoushadhi Simhanada Guggulu 500mg twice and Rasna Saptak Kwatha 40ml as Anupana for 45 days in both the groups with 1 month follow-up period. Both Group A and Group B provided highly significant results in all parameters of assessment but Kshara Vasti showed better improvement in the symptoms of the disease Amavata. 63.33% of patients got marked relief, 30% of patients got moderate relief. 56.66% of patients got marked relief in grip strength and 66.66% of the total number of patients got marked relief in tenderness. All the patients of both the groups responded well after Kshara Vasti and Vaitarana Vasti and the result were highly significant. The sustained affect of Vasti was very clearly evident after administration of Vasti along with Shamanoushadhi. Hence the modalities of our treatment can be recommended to all the patients of Amavata.


Author(s):  
Rajendra Joshi ◽  
N. B. Mashetti ◽  
Rakesh Kumar Gujar

Dushta Vrana is a common and frequently encountered problem faced in surgical practice. The presence of Dushta Vrana worsens the condition of the patient with different complications and may become fatal. Local factors on wound like slough, infection and foreign body, affect the normal process of healing. A healthy wound in a normal body heals earlier with a minimum scar as compared to a contaminated wound. Therefore in this study all the efforts are made to make a Dushta Vrana into a Shuddha Vrana. Once the Vrana becomes Shuddha, Ropana of the Vrana will start. The objective of the study was to evaluate the clinical efficacy of Jatyadi Taila and Jatyadi Ghrita in Dushta Vrana. Clinically diagnosed 60 Patients of Dushta Vrana were randomly divided into two groups, each consisting of 30 Patients. Group A were treated with the Jatyadi Taila and Group B was treated by Jatyadi Ghrita. The results observed was based on the relief obtained on the subjective and objective parameters taken for consideration for this study viz, size of ulcer, discharge, smell, pain, burning sensation, itching and granulation were found significant (P Lass Than 0.05). On the basis of assessment criteria and overall result of treatment, the patients of Jatyadi Taila group showed better results when compared to Jatyadi Ghrita group. Even though statistically there is no much significant difference between the two groups, but by seeing the effect on individual parameters (subjective and objective) and over all response, Jatyadi Taila seems to be effective when compared to Jatyadi Ghrita. It is having more Ropana qualities when compared to Shodhana.


2020 ◽  
Vol 5 (02) ◽  
pp. 22-29
Author(s):  
K. M. Bhavana ◽  
Umesh C. ◽  
Neelakanta Sajjanar ◽  
Gopala Krishna G.

Background: Vatarakta is a disease which is said to affect the population indulging in sedentary lifestyle. In today’s era the evolution of technology has reached a point where pretty much anything is available at the touch of a button. The lifestyle of today’s population is breeding ground for diseases like Vatarakta. Based on the causes, signs and symptoms, Vatarakta may be correlated to gouty arthritis in contemporary medicine. Gout affects about 2.1 million worldwide. Its prevalence is increasing; moreover it is a potential signal for unrecognized co-morbidities like obesity, diabetes mellitus, hypertension and renal diseases. In India the prevalence of gout is 2-6 per 1000. The purpose of this study is to explore and find out an effective, less expensive, easily available and well accepted drug with minimal or no complications for this dreadful condition. Materials and Methods: 40 patients diagnosed with Vatarakta w.s.r Gouty Arthritis were assigned randomly into 2 groups. Group A, were administered Bodhi Vruksha Twak Kashaya 50ml B.I.D with Madhu and Group B were administered Guduchi Kashaya 50ml B.I.D for a duration of 30 days. Assessment was done on day 0, day 15, day 30, and day 45. Observations and Results: In the present study Group A showed statistical significant results in all the parameters except for Sandhishotha and group B showed statistical significant result in Sandhishoola, Sandhidaha, Sparshasahaishnuta and uric acid levels. Conclusion: Overall result shows patients treated with Guduchi Kashaya showed better results than patients treated with Bodhi Vruksha Twak Kashaya with Madhu in Vatarakta with special reference to Gouty Arthritis.


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